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Hypoxia-inducible factor (HIF)-prolyl hydroxylase 3 (PHD3) maintains high HIF2A mRNA levels in clear cell renal cell carcinoma

  • Petra Miikkulainen
  • , Heidi Högel
  • , Fatemeh Seyednasrollah
  • , Krista Rantanen
  • , Laura L. Elo
  • , Panu M. Jaakkola

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalJournal of Biological Chemistry
Volume294
Issue number10
Pages (from-to)3760-3771
Number of pages12
ISSN0021-9258
DOIs
Publication statusPublished - 8 Mar 2019
MoE publication typeA1 Journal article-refereed

Fields of Science

  • cancer
  • cancer biology
  • hypoxia
  • hypoxia-inducible factor (HIF)
  • mRNA decay
  • ccRCC
  • Egl-9 family hypoxia-inducible factor 3 (EGLN3)
  • post-transcriptional regulation
  • prolyl hydroxylase PHD3
  • renal cell carcinoma
  • PROLYL HYDROXYLASES
  • GENE-EXPRESSION
  • TRANSCRIPTION
  • HIF-1-ALPHA
  • PROTEIN
  • TRANSLATION
  • PROTEASOME
  • STABILITY
  • CANCER
  • HIF-1
  • 1182 Biochemistry, cell and molecular biology
  • 3122 Cancers

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