Identification of Glycochenodeoxycholate 3-O-glucuronide and Glycodeoxycholate 3-O-glucuronide as Highly Sensitive and Specific OATP1B1 Biomarkers

Mikko Neuvonen, Päivi Hirvensalo, Aleksi Tornio, Brian Rago, Mark West, Sarah Lazzaro, Sumathy Mathialagan, Manthena Varma, Matthew A. Cerny, Chester Costales, Ragu Ramanathan, A. David Rodrigues, Mikko Niemi

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalClinical Pharmacology and Therapeutics
Number of pages12
ISSN0009-9236
DOIs
Publication statusE-pub ahead of print - 18 Oct 2020
MoE publication typeA1 Journal article-refereed

Fields of Science

  • ANION TRANSPORTING POLYPEPTIDE
  • POLYMORPHISM MARKEDLY AFFECTS
  • SLCO1B1 POLYMORPHISM
  • ENDOGENOUS BIOMARKERS
  • HAPLOTYPE RECONSTRUCTION
  • PLASMA-CONCENTRATIONS
  • CYNOMOLGUS MONKEYS
  • DRUG-INTERACTION
  • GENOME-WIDE
  • BILE-ACIDS

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