Identification of Gut Microbial Lysine and Histidine Degradation and CYP-Dependent Metabolites as Biomarkers of Fatty Liver Disease

Anastasiia Driuchina; Jukka Hintikka; Marko Lehtonen; Pekka Keski-Rahkonen; Thomas O'Connell; Risto Juvonen; Juho Kuula; Antti Hakkarainen; Jari A. Laukkanen; Elina Mäkinen; Sanna Lensu; Kirsi H. Pietiläinen; Satu Pekkala

doi:10.1128/mbio.02663-22

Identification of Gut Microbial Lysine and Histidine Degradation and CYP-Dependent Metabolites as Biomarkers of Fatty Liver Disease

Anastasiia Driuchina, Jukka Hintikka, Marko Lehtonen, Pekka Keski-Rahkonen, Thomas O'Connell, Risto Juvonen, Juho Kuula, Antti Hakkarainen, Jari A. Laukkanen, Elina Mäkinen, Sanna Lensu, Kirsi H. Pietiläinen, Satu Pekkala

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	mBio
Volume	14
Issue number	1
Number of pages	13
ISSN	2161-2129
DOIs	https://doi.org/10.1128/mbio.02663-22
Publication status	Published - 28 Feb 2023
MoE publication type	A1 Journal article-refereed

Fields of Science

11832 Microbiology and virology

Access to Document

10.1128/mbio.02663-22

mbio.02663-22Final published version, 2.15 MBLicence: CC BY

Cite this

Driuchina, A., Hintikka, J., Lehtonen, M., Keski-Rahkonen, P., O'Connell, T., Juvonen, R., Kuula, J., Hakkarainen, A., Laukkanen, J. A., Mäkinen, E., Lensu, S., Pietiläinen, K. H., & Pekkala, S. (2023). Identification of Gut Microbial Lysine and Histidine Degradation and CYP-Dependent Metabolites as Biomarkers of Fatty Liver Disease. mBio, 14(1). https://doi.org/10.1128/mbio.02663-22

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keywords = "Gut microbiota, Insulin resistance, Liver fat, Metabolomics, 11832 Microbiology and virology",

author = "Anastasiia Driuchina and Jukka Hintikka and Marko Lehtonen and Pekka Keski-Rahkonen and Thomas O'Connell and Risto Juvonen and Juho Kuula and Antti Hakkarainen and Laukkanen, {Jari A.} and Elina M{\"a}kinen and Sanna Lensu and Pietil{\"a}inen, {Kirsi H.} and Satu Pekkala",

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doi = "10.1128/mbio.02663-22",

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Driuchina, A, Hintikka, J, Lehtonen, M, Keski-Rahkonen, P, O'Connell, T, Juvonen, R, Kuula, J , Hakkarainen, A, Laukkanen, JA, Mäkinen, E, Lensu, S, Pietiläinen, KH & Pekkala, S 2023, 'Identification of Gut Microbial Lysine and Histidine Degradation and CYP-Dependent Metabolites as Biomarkers of Fatty Liver Disease', mBio, vol. 14, no. 1. https://doi.org/10.1128/mbio.02663-22

TY - JOUR

T1 - Identification of Gut Microbial Lysine and Histidine Degradation and CYP-Dependent Metabolites as Biomarkers of Fatty Liver Disease

AU - Driuchina, Anastasiia

AU - Hintikka, Jukka

AU - Lehtonen, Marko

AU - Keski-Rahkonen, Pekka

AU - O'Connell, Thomas

AU - Juvonen, Risto

AU - Kuula, Juho

AU - Hakkarainen, Antti

AU - Laukkanen, Jari A.

AU - Mäkinen, Elina

AU - Lensu, Sanna

AU - Pietiläinen, Kirsi H.

AU - Pekkala, Satu

PY - 2023/2/28

Y1 - 2023/2/28

KW - Gut microbiota

KW - Insulin resistance

KW - Liver fat

KW - Metabolomics

KW - 11832 Microbiology and virology

U2 - 10.1128/mbio.02663-22

DO - 10.1128/mbio.02663-22

M3 - Article

C2 - 36715540

SN - 2161-2129

VL - 14

JO - mBio

JF - mBio

IS - 1

ER -