Impaired hepatic lipid synthesis from polyunsaturated fatty acids in TM6SF2 E167K variant carriers with NAFLD

Panu K. Luukkonen, You Zhou, Nidhina P. A. Haridas, Om P. Dwivedi, Tuulia Hyotylainen, Ashfaq Ali, Anne Juuti, Marja Leivonen, Taru Tukiainen, Linda Ahonen, Emma Scott, Jeremy M. Palmer, Johanna Arola, Marju Orho-Melander, Petter Vikman, Quentin M. Anstee, Vesa M. Olkkonen, Matej Oresic, Leif Groop, Hannele Yki-Jarvinen

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalJournal of Hepatology
Volume67
Issue number1
Pages (from-to)128-136
Number of pages9
ISSN0168-8278
DOIs
Publication statusPublished - Jul 2017
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Transmembrane 6 superfamily member 2
  • Triglycerides
  • Cholesterol esters
  • Arachidonic acid
  • Phosphatidylcholines
  • Non-alcoholic fatty liver disease
  • Lipogenesis
  • Genotype
  • Hepatocytes
  • Fatty acids
  • LOW-DENSITY LIPOPROTEINS
  • SUPERFAMILY MEMBER 2
  • PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE
  • LIVER-DISEASE
  • NONALCOHOLIC STEATOHEPATITIS
  • CARDIOVASCULAR-DISEASE
  • INSULIN-RESISTANCE
  • FIBROSIS PROGRESSION
  • ARACHIDONIC-ACID
  • APOLIPOPROTEIN-B
  • 3121 General medicine, internal medicine and other clinical medicine

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