Implications of melanin binding in ocular drug delivery

Anna-Kaisa Rimpelä, Mika Reinisalo, Laura Hellinen, Evgeni Grazhdankin, Heidi Kidron, Arto Urtti, Eva M. del Amo

Research output: Contribution to journalReview ArticleScientificpeer-review

Original languageEnglish
JournalAdvanced Drug Delivery Reviews
Volume126
Pages (from-to)23-43
Number of pages21
ISSN0169-409X
DOIs
Publication statusPublished - 15 Feb 2018
MoE publication typeA2 Review article in a scientific journal

Fields of Science

  • Ocular melanin
  • Melanosomes
  • Pigment binding
  • Pharmacokinetics
  • Pharmacodynamics
  • Pharmacokinetic simulations
  • QSAR
  • RETINAL-PIGMENT-EPITHELIUM
  • PLURIPOTENT STEM-CELLS
  • HUMAN CHOROIDAL MELANOCYTES
  • WHOLE-BODY AUTORADIOGRAPHY
  • SYNTHETIC LEVODOPA MELANIN
  • IN-VITRO
  • UVEAL MELANOCYTES
  • 5,6-DIHYDROXYINDOLE-2-CARBOXYLIC ACID
  • TRANSSCLERAL DELIVERY
  • DOPA-MELANIN
  • 317 Pharmacy

Cite this

Rimpelä, Anna-Kaisa ; Reinisalo, Mika ; Hellinen, Laura ; Grazhdankin, Evgeni ; Kidron, Heidi ; Urtti, Arto ; del Amo, Eva M. / Implications of melanin binding in ocular drug delivery. In: Advanced Drug Delivery Reviews. 2018 ; Vol. 126. pp. 23-43.
@article{9467269e6779431ab60a90fe6d23dca0,
title = "Implications of melanin binding in ocular drug delivery",
keywords = "Ocular melanin, Melanosomes, Pigment binding, Pharmacokinetics, Pharmacodynamics, Pharmacokinetic simulations, QSAR, RETINAL-PIGMENT-EPITHELIUM, PLURIPOTENT STEM-CELLS, HUMAN CHOROIDAL MELANOCYTES, WHOLE-BODY AUTORADIOGRAPHY, SYNTHETIC LEVODOPA MELANIN, IN-VITRO, UVEAL MELANOCYTES, 5,6-DIHYDROXYINDOLE-2-CARBOXYLIC ACID, TRANSSCLERAL DELIVERY, DOPA-MELANIN, 317 Pharmacy",
author = "Anna-Kaisa Rimpel{\"a} and Mika Reinisalo and Laura Hellinen and Evgeni Grazhdankin and Heidi Kidron and Arto Urtti and {del Amo}, {Eva M.}",
year = "2018",
month = "2",
day = "15",
doi = "10.1016/j.addr.2017.12.008",
language = "English",
volume = "126",
pages = "23--43",
journal = "Advanced Drug Delivery Reviews",
issn = "0169-409X",
publisher = "Elsevier Scientific Publ. Co",

}

Implications of melanin binding in ocular drug delivery. / Rimpelä, Anna-Kaisa; Reinisalo, Mika; Hellinen, Laura; Grazhdankin, Evgeni; Kidron, Heidi; Urtti, Arto; del Amo, Eva M.

In: Advanced Drug Delivery Reviews, Vol. 126, 15.02.2018, p. 23-43.

Research output: Contribution to journalReview ArticleScientificpeer-review

TY - JOUR

T1 - Implications of melanin binding in ocular drug delivery

AU - Rimpelä, Anna-Kaisa

AU - Reinisalo, Mika

AU - Hellinen, Laura

AU - Grazhdankin, Evgeni

AU - Kidron, Heidi

AU - Urtti, Arto

AU - del Amo, Eva M.

PY - 2018/2/15

Y1 - 2018/2/15

KW - Ocular melanin

KW - Melanosomes

KW - Pigment binding

KW - Pharmacokinetics

KW - Pharmacodynamics

KW - Pharmacokinetic simulations

KW - QSAR

KW - RETINAL-PIGMENT-EPITHELIUM

KW - PLURIPOTENT STEM-CELLS

KW - HUMAN CHOROIDAL MELANOCYTES

KW - WHOLE-BODY AUTORADIOGRAPHY

KW - SYNTHETIC LEVODOPA MELANIN

KW - IN-VITRO

KW - UVEAL MELANOCYTES

KW - 5,6-DIHYDROXYINDOLE-2-CARBOXYLIC ACID

KW - TRANSSCLERAL DELIVERY

KW - DOPA-MELANIN

KW - 317 Pharmacy

U2 - 10.1016/j.addr.2017.12.008

DO - 10.1016/j.addr.2017.12.008

M3 - Review Article

VL - 126

SP - 23

EP - 43

JO - Advanced Drug Delivery Reviews

JF - Advanced Drug Delivery Reviews

SN - 0169-409X

ER -