In Vitro Assessment of Time-Dependent Inhibitory Effects on CYP2C8 and CYP3A Activity by Fourteen Protein Kinase Inhibitors

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalDrug Metabolism and Disposition
Volume42
Issue number7
Pages (from-to)1202-1209
Number of pages8
ISSN0090-9556
DOIs
Publication statusPublished - Jul 2014
MoE publication typeA1 Journal article-refereed

Fields of Science

  • DRUG-DRUG INTERACTIONS
  • HUMAN CYTOCHROME-P450 ENZYMES
  • MECHANISM-BASED INACTIVATION
  • HUMAN LIVER-MICROSOMES
  • PLASMA-CONCENTRATIONS
  • CLINICAL PHARMACOKINETICS
  • BIOACTIVATION PATHWAYS
  • SOLID TUMORS
  • PHASE-I
  • GEMFIBROZIL
  • 3111 Biomedicine

Cite this