In Vitro Screening of Six Protein Kinase Inhibitors for Time-Dependent Inhibition of CYP2C8 and CYP3A4: Possible Implications with regard to Drug-Drug Interactions

Anne M. Filppula, Tiffany M. Mustonen, Janne T. Backman

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalBasic & Clinical Pharmacology & Toxicology
Volume123
Issue number6
Pages (from-to)739-748
Number of pages10
ISSN1742-7835
DOIs
Publication statusPublished - Dec 2018
MoE publication typeA1 Journal article-refereed

Fields of Science

  • MECHANISM-BASED INACTIVATION
  • ADVANCED SOLID TUMORS
  • BIOACTIVATION PATHWAYS
  • CYTOCHROME-P450 3A4
  • MYELOID-LEUKEMIA
  • LIVER-MICROSOMES
  • GRAPEFRUIT JUICE
  • BIBF 1120
  • PHASE-II
  • PREDICTION
  • 317 Pharmacy
  • 3111 Biomedicine

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