In-Vivo Antidiabetic Activity and In-Silico Mode of Action of LC/MS-MS Identified Flavonoids in Oleaster Leaves

Hamza Mechchate; Imane Es-Safi; Mohammed Bourhia; Andrii Kyrylchuk; Abdelfattah El Moussaoui; Raffaele Conte; Riaz Ullah; Essam Ezzeldin; Gamal A. Mostafa; Andriy Grafov; Hicham Bekkari; Dalila Bousta

doi:10.3390/molecules25215073

In-Vivo Antidiabetic Activity and In-Silico Mode of Action of LC/MS-MS Identified Flavonoids in Oleaster Leaves

Hamza Mechchate, Imane Es-Safi, Mohammed Bourhia, Andrii Kyrylchuk, Abdelfattah El Moussaoui, Raffaele Conte, Riaz Ullah, Essam Ezzeldin, Gamal A. Mostafa, Andriy Grafov, Hicham Bekkari, Dalila Bousta

Department of Chemistry

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	5073
Journal	Molecules
Volume	25
Issue number	21
Number of pages	13
ISSN	1420-3049
DOIs	https://doi.org/10.3390/molecules25215073
Publication status	Published - Nov 2020
MoE publication type	A1 Journal article-refereed

Fields of Science

Olea europea L
subsp
europaea var
sylvestris (Mill) Lehr
oleaster
diabetes
flavonoids
molecular docking
SALIVARY ALPHA-AMYLASE
INSULIN SENSITIVITY
CRYSTAL-STRUCTURES
AROMATIC RESIDUES
PROTEIN
RECOGNITION
ACTIVATION
MECHANISM
DOMAIN
1182 Biochemistry, cell and molecular biology

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10.3390/molecules25215073Licence: CC BY

molecules-25-05073Final published version, 893 KBLicence: CC BY

VAHVISTUS: Integrative development of smart drug-vector nanostructures for adaptive delivery to target cells
Grafov, A. (Project manager)
01/03/2017 → 28/02/2022
Project: Research project

Cite this

@article{28ff7f29d607418e93e688836baf1e05,

title = "In-Vivo Antidiabetic Activity and In-Silico Mode of Action of LC/MS-MS Identified Flavonoids in Oleaster Leaves",

keywords = "Olea europea L, subsp, europaea var, sylvestris (Mill) Lehr, oleaster, diabetes, flavonoids, molecular docking, SALIVARY ALPHA-AMYLASE, INSULIN SENSITIVITY, CRYSTAL-STRUCTURES, AROMATIC RESIDUES, PROTEIN, RECOGNITION, ACTIVATION, MECHANISM, DOMAIN, 1182 Biochemistry, cell and molecular biology",

author = "Hamza Mechchate and Imane Es-Safi and Mohammed Bourhia and Andrii Kyrylchuk and {El Moussaoui}, Abdelfattah and Raffaele Conte and Riaz Ullah and Essam Ezzeldin and Mostafa, {Gamal A.} and Andriy Grafov and Hicham Bekkari and Dalila Bousta",

year = "2020",

month = nov,

doi = "10.3390/molecules25215073",

language = "English",

volume = "25",

journal = "Molecules",

issn = "1420-3049",

publisher = "MDPI",

number = "21",

}

TY - JOUR

T1 - In-Vivo Antidiabetic Activity and In-Silico Mode of Action of LC/MS-MS Identified Flavonoids in Oleaster Leaves

AU - Mechchate, Hamza

AU - Es-Safi, Imane

AU - Bourhia, Mohammed

AU - Kyrylchuk, Andrii

AU - El Moussaoui, Abdelfattah

AU - Conte, Raffaele

AU - Ullah, Riaz

AU - Ezzeldin, Essam

AU - Mostafa, Gamal A.

AU - Grafov, Andriy

AU - Bekkari, Hicham

AU - Bousta, Dalila

PY - 2020/11

Y1 - 2020/11

KW - Olea europea L

KW - subsp

KW - europaea var

KW - sylvestris (Mill) Lehr

KW - oleaster

KW - diabetes

KW - flavonoids

KW - molecular docking

KW - SALIVARY ALPHA-AMYLASE

KW - INSULIN SENSITIVITY

KW - CRYSTAL-STRUCTURES

KW - AROMATIC RESIDUES

KW - PROTEIN

KW - RECOGNITION

KW - ACTIVATION

KW - MECHANISM

KW - DOMAIN

KW - 1182 Biochemistry, cell and molecular biology

U2 - 10.3390/molecules25215073

DO - 10.3390/molecules25215073

M3 - Article

SN - 1420-3049

VL - 25

JO - Molecules

JF - Molecules

IS - 21

M1 - 5073

ER -

In-Vivo Antidiabetic Activity and In-Silico Mode of Action of LC/MS-MS Identified Flavonoids in Oleaster Leaves

Fields of Science

Access to Document

Projects

VAHVISTUS: Integrative development of smart drug-vector nanostructures for adaptive delivery to target cells

Cite this