Including known covariates can reduce power to detect genetic effects in case-control studies

Matti Pirinen, Peter Donnelly, Chris C. A. Spencer

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalNature Genetics
Volume44
Issue number8
Pages (from-to)848-851
Number of pages4
ISSN1061-4036
DOIs
Publication statusPublished - Aug 2012
MoE publication typeA1 Journal article-refereed

Fields of Science

  • LOGISTIC-REGRESSION MODELS
  • GENERALIZED LINEAR-MODELS
  • EFFICIENCY
  • BIAS
  • 318 Medical biotechnology
  • 1184 Genetics, developmental biology, physiology

Cite this

Pirinen, Matti ; Donnelly, Peter ; Spencer, Chris C. A. / Including known covariates can reduce power to detect genetic effects in case-control studies. In: Nature Genetics. 2012 ; Vol. 44, No. 8. pp. 848-851.
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Including known covariates can reduce power to detect genetic effects in case-control studies. / Pirinen, Matti; Donnelly, Peter; Spencer, Chris C. A.

In: Nature Genetics, Vol. 44, No. 8, 08.2012, p. 848-851.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

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AU - Pirinen, Matti

AU - Donnelly, Peter

AU - Spencer, Chris C. A.

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KW - LOGISTIC-REGRESSION MODELS

KW - GENERALIZED LINEAR-MODELS

KW - EFFICIENCY

KW - BIAS

KW - 318 Medical biotechnology

KW - 1184 Genetics, developmental biology, physiology

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DO - 10.1038/ng.2346

M3 - Article

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SP - 848

EP - 851

JO - Nature Genetics

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SN - 1061-4036

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