Incorporation of 6-Thioguanine Nucleotides into DNA During Maintenance Therapy of Childhood Acute Lymphoblastic LeukemiaThe Influence of Thiopurine Methyltransferase Genotypes

Maria S. Ebbesen; Jacob Nersting; Jack H. Jacobsen; Thomas L. Frandsen; Kim Vettenranta; Jonas Abramsson; Finn Wesenberg; Kjeld Schmiegelow

doi:10.1002/jcph.81

Incorporation of 6-Thioguanine Nucleotides into DNA During Maintenance Therapy of Childhood Acute Lymphoblastic LeukemiaThe Influence of Thiopurine Methyltransferase Genotypes

Maria S. Ebbesen
, Jacob Nersting
, Jack H. Jacobsen
, Thomas L. Frandsen
, Kim Vettenranta
, Jonas Abramsson
, Finn Wesenberg
, Kjeld Schmiegelow

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Journal of Clinical Pharmacology
Volume	53
Issue number	6
Pages (from-to)	670-674
Number of pages	5
ISSN	0091-2700
DOIs	https://doi.org/10.1002/jcph.81
Publication status	Published - Jun 2013
Externally published	Yes
MoE publication type	A1 Journal article-refereed

Fields of Science

acute lymphoblastic leukemia
thiopurines
DNA-TG
thiopurine methyltransferase
maintenance therapy
LIQUID-CHROMATOGRAPHY
RANDOMIZED-TRIAL
NOPHO ALL-92
PHARMACOGENETICS
TOXICITY
RISK
6-MERCAPTOPURINE
MERCAPTOPURINE
THIOGUANINE
METABOLISM
317 Pharmacy
3123 Gynaecology and paediatrics

Access to Document

10.1002/jcph.81

Cite this

Ebbesen, M. S., Nersting, J., Jacobsen, J. H., Frandsen, T. L., Vettenranta, K., Abramsson, J., Wesenberg, F., & Schmiegelow, K. (2013). Incorporation of 6-Thioguanine Nucleotides into DNA During Maintenance Therapy of Childhood Acute Lymphoblastic LeukemiaThe Influence of Thiopurine Methyltransferase Genotypes. Journal of Clinical Pharmacology, 53(6), 670-674. https://doi.org/10.1002/jcph.81

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title = "Incorporation of 6-Thioguanine Nucleotides into DNA During Maintenance Therapy of Childhood Acute Lymphoblastic LeukemiaThe Influence of Thiopurine Methyltransferase Genotypes",

keywords = "acute lymphoblastic leukemia, thiopurines, DNA-TG, thiopurine methyltransferase, maintenance therapy, LIQUID-CHROMATOGRAPHY, RANDOMIZED-TRIAL, NOPHO ALL-92, PHARMACOGENETICS, TOXICITY, RISK, 6-MERCAPTOPURINE, MERCAPTOPURINE, THIOGUANINE, METABOLISM, 317 Pharmacy, 3123 Gynaecology and paediatrics",

author = "Ebbesen, \{Maria S.\} and Jacob Nersting and Jacobsen, \{Jack H.\} and Frandsen, \{Thomas L.\} and Kim Vettenranta and Jonas Abramsson and Finn Wesenberg and Kjeld Schmiegelow",

year = "2013",

month = jun,

doi = "10.1002/jcph.81",

language = "English",

volume = "53",

pages = "670--674",

journal = "Journal of Clinical Pharmacology",

issn = "0091-2700",

publisher = "Wiley Blackwell",

number = "6",

}

Ebbesen, MS, Nersting, J, Jacobsen, JH, Frandsen, TL, Vettenranta, K, Abramsson, J, Wesenberg, F & Schmiegelow, K 2013, 'Incorporation of 6-Thioguanine Nucleotides into DNA During Maintenance Therapy of Childhood Acute Lymphoblastic LeukemiaThe Influence of Thiopurine Methyltransferase Genotypes', Journal of Clinical Pharmacology, vol. 53, no. 6, pp. 670-674. https://doi.org/10.1002/jcph.81

Incorporation of 6-Thioguanine Nucleotides into DNA During Maintenance Therapy of Childhood Acute Lymphoblastic LeukemiaThe Influence of Thiopurine Methyltransferase Genotypes. / Ebbesen, Maria S.; Nersting, Jacob; Jacobsen, Jack H. et al.
In: Journal of Clinical Pharmacology, Vol. 53, No. 6, 06.2013, p. 670-674.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Incorporation of 6-Thioguanine Nucleotides into DNA During Maintenance Therapy of Childhood Acute Lymphoblastic LeukemiaThe Influence of Thiopurine Methyltransferase Genotypes

AU - Ebbesen, Maria S.

AU - Nersting, Jacob

AU - Jacobsen, Jack H.

AU - Frandsen, Thomas L.

AU - Vettenranta, Kim

AU - Abramsson, Jonas

AU - Wesenberg, Finn

AU - Schmiegelow, Kjeld

PY - 2013/6

Y1 - 2013/6

KW - acute lymphoblastic leukemia

KW - thiopurines

KW - DNA-TG

KW - thiopurine methyltransferase

KW - maintenance therapy

KW - LIQUID-CHROMATOGRAPHY

KW - RANDOMIZED-TRIAL

KW - NOPHO ALL-92

KW - PHARMACOGENETICS

KW - TOXICITY

KW - RISK

KW - 6-MERCAPTOPURINE

KW - MERCAPTOPURINE

KW - THIOGUANINE

KW - METABOLISM

KW - 317 Pharmacy

KW - 3123 Gynaecology and paediatrics

U2 - 10.1002/jcph.81

DO - 10.1002/jcph.81

M3 - Article

SN - 0091-2700

VL - 53

SP - 670

EP - 674

JO - Journal of Clinical Pharmacology

JF - Journal of Clinical Pharmacology

IS - 6

ER -