Inside Front Cover - Neuroprotection: Biodegradable Spheres Protect Traumatically Injured Spinal Cord by Alleviating the Glutamate‐Induced Excitotoxicity (Adv. Mater. 14/2018)

Dongfei Liu, Jian Chen, Tao Jiang, Wei Li, Zehua Liu, Yao Huang, Xiyi Lu, Weixia Zhang, Zheng Zhou, Qirui Ding, Helder Almeida Santos, Guoyong Yin, Jin Fan

Research output: Non-textual formDesignArt in non-art workpeer-review

Abstract

New treatment strategies for spinal‐cord injury are being actively pursued. In article number 1706032, Hélder A. Santos, Guoyong Yin, Jin Fan, and co‐workers show that intrathecally injected biodegradable polymeric microspheres, acetalated dextran, can protect traumatically injured spinal cord. The neuroprotective feature of acetalated dextran microspheres is achieved by sequestering the excessive glutamate and calcium ions in cerebrospinal fluid, and consequently attenuating the glutamateinduced excitotoxicity.
Original languageEnglish
Edition14
DOIs
Publication statusPublished - 14 Feb 2018
MoE publication typeNot Eligible

Fields of Science

  • 6132 Visual arts and design

Cite this

Liu, Dongfei (Author) ; Chen, Jian (Author) ; Jiang, Tao (Author) ; Li, Wei (Author) ; Liu, Zehua (Author) ; Huang, Yao (Author) ; Lu, Xiyi (Author) ; Zhang, Weixia (Author) ; Zhou, Zheng (Author) ; Ding, Qirui (Author) ; Almeida Santos, Helder (Author) ; Yin, Guoyong (Author) ; Fan, Jin (Author). / Inside Front Cover - Neuroprotection: Biodegradable Spheres Protect Traumatically Injured Spinal Cord by Alleviating the Glutamate‐Induced Excitotoxicity (Adv. Mater. 14/2018). [Design].
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abstract = "New treatment strategies for spinal‐cord injury are being actively pursued. In article number 1706032, H{\'e}lder A. Santos, Guoyong Yin, Jin Fan, and co‐workers show that intrathecally injected biodegradable polymeric microspheres, acetalated dextran, can protect traumatically injured spinal cord. The neuroprotective feature of acetalated dextran microspheres is achieved by sequestering the excessive glutamate and calcium ions in cerebrospinal fluid, and consequently attenuating the glutamateinduced excitotoxicity.",
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author = "Dongfei Liu and Jian Chen and Tao Jiang and Wei Li and Zehua Liu and Yao Huang and Xiyi Lu and Weixia Zhang and Zheng Zhou and Qirui Ding and {Almeida Santos}, Helder and Guoyong Yin and Jin Fan",
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Inside Front Cover - Neuroprotection: Biodegradable Spheres Protect Traumatically Injured Spinal Cord by Alleviating the Glutamate‐Induced Excitotoxicity (Adv. Mater. 14/2018). Liu, Dongfei (Author); Chen, Jian (Author); Jiang, Tao (Author); Li, Wei (Author); Liu, Zehua (Author); Huang, Yao (Author); Lu, Xiyi (Author); Zhang, Weixia (Author); Zhou, Zheng (Author); Ding, Qirui (Author); Almeida Santos, Helder (Author); Yin, Guoyong (Author); Fan, Jin (Author). 2018.

Research output: Non-textual formDesignArt in non-art workpeer-review

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T1 - Inside Front Cover - Neuroprotection: Biodegradable Spheres Protect Traumatically Injured Spinal Cord by Alleviating the Glutamate‐Induced Excitotoxicity (Adv. Mater. 14/2018)

AU - Liu, Dongfei

AU - Chen, Jian

AU - Jiang, Tao

AU - Li, Wei

AU - Liu, Zehua

AU - Huang, Yao

AU - Lu, Xiyi

AU - Zhang, Weixia

AU - Zhou, Zheng

AU - Ding, Qirui

AU - Almeida Santos, Helder

AU - Yin, Guoyong

AU - Fan, Jin

PY - 2018/2/14

Y1 - 2018/2/14

N2 - New treatment strategies for spinal‐cord injury are being actively pursued. In article number 1706032, Hélder A. Santos, Guoyong Yin, Jin Fan, and co‐workers show that intrathecally injected biodegradable polymeric microspheres, acetalated dextran, can protect traumatically injured spinal cord. The neuroprotective feature of acetalated dextran microspheres is achieved by sequestering the excessive glutamate and calcium ions in cerebrospinal fluid, and consequently attenuating the glutamateinduced excitotoxicity.

AB - New treatment strategies for spinal‐cord injury are being actively pursued. In article number 1706032, Hélder A. Santos, Guoyong Yin, Jin Fan, and co‐workers show that intrathecally injected biodegradable polymeric microspheres, acetalated dextran, can protect traumatically injured spinal cord. The neuroprotective feature of acetalated dextran microspheres is achieved by sequestering the excessive glutamate and calcium ions in cerebrospinal fluid, and consequently attenuating the glutamateinduced excitotoxicity.

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