Integrated analysis of population genomics, transcriptomics and virulence provides novel insights into Streptococcus pyogenes pathogenesis

Priyanka Kachroo, Jesus M. Eraso, Stephen B. Beres, Randall J. Olsen, Luchang Zhu, Waleed Nasser, Paul E. Bernard, Concepcion C. Cantu, Matthew Ojeda Saavedra, Maria Jose Arredondo, Benjamin Strope, Hackwon Do, Muthiah Kumaraswami, Jaana Vuopio, Kirsi Gröndahl-Yli-Hannuksela, Karl G. Kristinsson, Magnus Gottfredsson, Maiju Pesonen, Johan Pensar, Emily R. Davenport & 11 others Andrew G. Clark, Jukka Corander, Dominique A. Caugant, Shahin Gaini, Marita Debess Magnussen, Samantha L. Kubiak, Hoang A. T. Nguyen, S. Wesley Long, Adeline R. Porter, Frank R. DeLeo, James M. Musser

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalNature Genetics
Volume51
Issue number3
Pages (from-to)548-563
Number of pages15
ISSN1061-4036
DOIs
Publication statusPublished - Mar 2019
MoE publication typeA1 Journal article-refereed

Fields of Science

  • GROUP-A STREPTOCOCCUS
  • REGULATORY SYSTEM
  • PUERPERAL SEPSIS
  • RHEUMATIC-FEVER
  • GENE-EXPRESSION
  • EMM TYPES
  • SEQUENCE
  • INFECTIONS
  • BACTERIAL
  • PROTEIN
  • 1184 Genetics, developmental biology, physiology

Cite this

Kachroo, Priyanka ; Eraso, Jesus M. ; Beres, Stephen B. ; Olsen, Randall J. ; Zhu, Luchang ; Nasser, Waleed ; Bernard, Paul E. ; Cantu, Concepcion C. ; Saavedra, Matthew Ojeda ; Arredondo, Maria Jose ; Strope, Benjamin ; Do, Hackwon ; Kumaraswami, Muthiah ; Vuopio, Jaana ; Gröndahl-Yli-Hannuksela, Kirsi ; Kristinsson, Karl G. ; Gottfredsson, Magnus ; Pesonen, Maiju ; Pensar, Johan ; Davenport, Emily R. ; Clark, Andrew G. ; Corander, Jukka ; Caugant, Dominique A. ; Gaini, Shahin ; Magnussen, Marita Debess ; Kubiak, Samantha L. ; Nguyen, Hoang A. T. ; Long, S. Wesley ; Porter, Adeline R. ; DeLeo, Frank R. ; Musser, James M. / Integrated analysis of population genomics, transcriptomics and virulence provides novel insights into Streptococcus pyogenes pathogenesis. In: Nature Genetics. 2019 ; Vol. 51, No. 3. pp. 548-563.
@article{d4232858314e4ba4a5c52e80c7433a95,
title = "Integrated analysis of population genomics, transcriptomics and virulence provides novel insights into Streptococcus pyogenes pathogenesis",
keywords = "GROUP-A STREPTOCOCCUS, REGULATORY SYSTEM, PUERPERAL SEPSIS, RHEUMATIC-FEVER, GENE-EXPRESSION, EMM TYPES, SEQUENCE, INFECTIONS, BACTERIAL, PROTEIN, 1184 Genetics, developmental biology, physiology",
author = "Priyanka Kachroo and Eraso, {Jesus M.} and Beres, {Stephen B.} and Olsen, {Randall J.} and Luchang Zhu and Waleed Nasser and Bernard, {Paul E.} and Cantu, {Concepcion C.} and Saavedra, {Matthew Ojeda} and Arredondo, {Maria Jose} and Benjamin Strope and Hackwon Do and Muthiah Kumaraswami and Jaana Vuopio and Kirsi Gr{\"o}ndahl-Yli-Hannuksela and Kristinsson, {Karl G.} and Magnus Gottfredsson and Maiju Pesonen and Johan Pensar and Davenport, {Emily R.} and Clark, {Andrew G.} and Jukka Corander and Caugant, {Dominique A.} and Shahin Gaini and Magnussen, {Marita Debess} and Kubiak, {Samantha L.} and Nguyen, {Hoang A. T.} and Long, {S. Wesley} and Porter, {Adeline R.} and DeLeo, {Frank R.} and Musser, {James M.}",
year = "2019",
month = "3",
doi = "10.1038/s41588-018-0343-1",
language = "English",
volume = "51",
pages = "548--563",
journal = "Nature Genetics",
issn = "1061-4036",
publisher = "Nature Publishing Group",
number = "3",

}

Kachroo, P, Eraso, JM, Beres, SB, Olsen, RJ, Zhu, L, Nasser, W, Bernard, PE, Cantu, CC, Saavedra, MO, Arredondo, MJ, Strope, B, Do, H, Kumaraswami, M, Vuopio, J, Gröndahl-Yli-Hannuksela, K, Kristinsson, KG, Gottfredsson, M, Pesonen, M, Pensar, J, Davenport, ER, Clark, AG, Corander, J, Caugant, DA, Gaini, S, Magnussen, MD, Kubiak, SL, Nguyen, HAT, Long, SW, Porter, AR, DeLeo, FR & Musser, JM 2019, 'Integrated analysis of population genomics, transcriptomics and virulence provides novel insights into Streptococcus pyogenes pathogenesis', Nature Genetics, vol. 51, no. 3, pp. 548-563. https://doi.org/10.1038/s41588-018-0343-1

Integrated analysis of population genomics, transcriptomics and virulence provides novel insights into Streptococcus pyogenes pathogenesis. / Kachroo, Priyanka; Eraso, Jesus M.; Beres, Stephen B.; Olsen, Randall J.; Zhu, Luchang; Nasser, Waleed; Bernard, Paul E.; Cantu, Concepcion C.; Saavedra, Matthew Ojeda; Arredondo, Maria Jose; Strope, Benjamin; Do, Hackwon; Kumaraswami, Muthiah; Vuopio, Jaana; Gröndahl-Yli-Hannuksela, Kirsi; Kristinsson, Karl G.; Gottfredsson, Magnus; Pesonen, Maiju; Pensar, Johan; Davenport, Emily R.; Clark, Andrew G.; Corander, Jukka; Caugant, Dominique A.; Gaini, Shahin; Magnussen, Marita Debess; Kubiak, Samantha L.; Nguyen, Hoang A. T.; Long, S. Wesley; Porter, Adeline R.; DeLeo, Frank R.; Musser, James M.

In: Nature Genetics, Vol. 51, No. 3, 03.2019, p. 548-563.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Integrated analysis of population genomics, transcriptomics and virulence provides novel insights into Streptococcus pyogenes pathogenesis

AU - Kachroo, Priyanka

AU - Eraso, Jesus M.

AU - Beres, Stephen B.

AU - Olsen, Randall J.

AU - Zhu, Luchang

AU - Nasser, Waleed

AU - Bernard, Paul E.

AU - Cantu, Concepcion C.

AU - Saavedra, Matthew Ojeda

AU - Arredondo, Maria Jose

AU - Strope, Benjamin

AU - Do, Hackwon

AU - Kumaraswami, Muthiah

AU - Vuopio, Jaana

AU - Gröndahl-Yli-Hannuksela, Kirsi

AU - Kristinsson, Karl G.

AU - Gottfredsson, Magnus

AU - Pesonen, Maiju

AU - Pensar, Johan

AU - Davenport, Emily R.

AU - Clark, Andrew G.

AU - Corander, Jukka

AU - Caugant, Dominique A.

AU - Gaini, Shahin

AU - Magnussen, Marita Debess

AU - Kubiak, Samantha L.

AU - Nguyen, Hoang A. T.

AU - Long, S. Wesley

AU - Porter, Adeline R.

AU - DeLeo, Frank R.

AU - Musser, James M.

PY - 2019/3

Y1 - 2019/3

KW - GROUP-A STREPTOCOCCUS

KW - REGULATORY SYSTEM

KW - PUERPERAL SEPSIS

KW - RHEUMATIC-FEVER

KW - GENE-EXPRESSION

KW - EMM TYPES

KW - SEQUENCE

KW - INFECTIONS

KW - BACTERIAL

KW - PROTEIN

KW - 1184 Genetics, developmental biology, physiology

U2 - 10.1038/s41588-018-0343-1

DO - 10.1038/s41588-018-0343-1

M3 - Article

VL - 51

SP - 548

EP - 563

JO - Nature Genetics

JF - Nature Genetics

SN - 1061-4036

IS - 3

ER -