Integrated drug profiling and CRISPR screening identify essential pathways for CAR T-cell cytotoxicity

Olli Dufva, Jan Koski, Pilvi Maliniemi, Aleksandr Ianevski, Jay Klievink, Judith Leitner, Petri Pölönen, Helena Hohtari, Khalid Saeed, Tiina Hannunen, Pekka Ellonen, Peter Steinberger, Matti Kankainen, Tero Aittokallio, Mikko A. I. Keränen, Matti Korhonen, Satu Mustjoki

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalBlood
Volume135
Issue number9
Pages (from-to)597-609
Number of pages13
ISSN0006-4971
DOIs
Publication statusPublished - 27 Feb 2020
MoE publication typeA1 Journal article-refereed

Fields of Science

  • SMAC-MIMETIC BIRINAPANT
  • PHASE-I
  • ACTIVATION
  • COSTIMULATION
  • PROTEINS
  • IMMUNE
  • IMMUNOTHERAPY
  • RESISTANCE
  • INHIBITORS
  • STRATEGY
  • 3111 Biomedicine
  • 3121 General medicine, internal medicine and other clinical medicine

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