Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

David M. Evans, Chris C. A. Spencer, Jennifer J. Pointon, Zhan Su, David Harvey, Grazyna Kochan, Udo Opperman, Alexander Dilthey, Matti Pirinen, Millicent A. Stone, Louise Appleton, Loukas Moutsianis, Stephen Leslie, Tom Wordsworth, Tony J. Kenna, Tugce Karaderi, Gethin P. Thomas, Michael M. Ward, Michael H. Weisman, Claire FarrarLinda A. Bradbury, Patrick Danoy, Robert D. Inman, Walter Maksymowych, Dafna Gladman, Proton Rahman, Ann Morgan, Helena Marzo-Ortega, Paul Bowness, Karl Gaffney, J. S. Hill Gaston, Malcolm Smith, Jacome Bruges-Armas, Ana-Rita Couto, Rosa Sorrentino, Fabiana Paladini, Manuel A. Ferreira, Huji Xu, Yu Liu, Lei Jiang, Carlos Lopez-Larrea, Roberto Diaz-Pena, Antonio Lopez-Vazquez, Tetyana Zayats, Gavin Band, Celine Bellenguez, Hannah Blackburn, Jenefer M. Blackwell, Leena Palotie, Anna Rautanen, Australo-Anglo-Amer Spondyloarthri, Wellcome Trust Case Control Consor, Spondyloarthrit Res Consortium Can

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalNature Genetics
Volume43
Issue number8
Pages (from-to)761-767
Number of pages7
ISSN1061-4036
DOIs
Publication statusPublished - Aug 2011
MoE publication typeA1 Journal article-refereed

Fields of Science

  • GENOME-WIDE ASSOCIATION
  • INFLAMMATORY-BOWEL-DISEASE
  • GENETIC ASSOCIATION
  • TRIMS PRECURSORS
  • AMINOPEPTIDASE
  • RISK
  • HLA
  • POPULATION
  • PROMOTES
  • CELLS
  • 318 Medical biotechnology
  • 1184 Genetics, developmental biology, physiology

Cite this

Evans, D. M., Spencer, C. C. A., Pointon, J. J., Su, Z., Harvey, D., Kochan, G., ... Spondyloarthrit Res Consortium Can (2011). Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. Nature Genetics, 43(8), 761-767. https://doi.org/10.1038/ng.873
Evans, David M. ; Spencer, Chris C. A. ; Pointon, Jennifer J. ; Su, Zhan ; Harvey, David ; Kochan, Grazyna ; Opperman, Udo ; Dilthey, Alexander ; Pirinen, Matti ; Stone, Millicent A. ; Appleton, Louise ; Moutsianis, Loukas ; Leslie, Stephen ; Wordsworth, Tom ; Kenna, Tony J. ; Karaderi, Tugce ; Thomas, Gethin P. ; Ward, Michael M. ; Weisman, Michael H. ; Farrar, Claire ; Bradbury, Linda A. ; Danoy, Patrick ; Inman, Robert D. ; Maksymowych, Walter ; Gladman, Dafna ; Rahman, Proton ; Morgan, Ann ; Marzo-Ortega, Helena ; Bowness, Paul ; Gaffney, Karl ; Gaston, J. S. Hill ; Smith, Malcolm ; Bruges-Armas, Jacome ; Couto, Ana-Rita ; Sorrentino, Rosa ; Paladini, Fabiana ; Ferreira, Manuel A. ; Xu, Huji ; Liu, Yu ; Jiang, Lei ; Lopez-Larrea, Carlos ; Diaz-Pena, Roberto ; Lopez-Vazquez, Antonio ; Zayats, Tetyana ; Band, Gavin ; Bellenguez, Celine ; Blackburn, Hannah ; Blackwell, Jenefer M. ; Palotie, Leena ; Rautanen, Anna ; Australo-Anglo-Amer Spondyloarthri ; Wellcome Trust Case Control Consor ; Spondyloarthrit Res Consortium Can. / Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. In: Nature Genetics. 2011 ; Vol. 43, No. 8. pp. 761-767.
@article{8aa4bcd26d614c529a12f7b8a091d046,
title = "Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility",
keywords = "GENOME-WIDE ASSOCIATION, INFLAMMATORY-BOWEL-DISEASE, GENETIC ASSOCIATION, TRIMS PRECURSORS, AMINOPEPTIDASE, RISK, HLA, POPULATION, PROMOTES, CELLS, 318 Medical biotechnology, 1184 Genetics, developmental biology, physiology",
author = "Evans, {David M.} and Spencer, {Chris C. A.} and Pointon, {Jennifer J.} and Zhan Su and David Harvey and Grazyna Kochan and Udo Opperman and Alexander Dilthey and Matti Pirinen and Stone, {Millicent A.} and Louise Appleton and Loukas Moutsianis and Stephen Leslie and Tom Wordsworth and Kenna, {Tony J.} and Tugce Karaderi and Thomas, {Gethin P.} and Ward, {Michael M.} and Weisman, {Michael H.} and Claire Farrar and Bradbury, {Linda A.} and Patrick Danoy and Inman, {Robert D.} and Walter Maksymowych and Dafna Gladman and Proton Rahman and Ann Morgan and Helena Marzo-Ortega and Paul Bowness and Karl Gaffney and Gaston, {J. S. Hill} and Malcolm Smith and Jacome Bruges-Armas and Ana-Rita Couto and Rosa Sorrentino and Fabiana Paladini and Ferreira, {Manuel A.} and Huji Xu and Yu Liu and Lei Jiang and Carlos Lopez-Larrea and Roberto Diaz-Pena and Antonio Lopez-Vazquez and Tetyana Zayats and Gavin Band and Celine Bellenguez and Hannah Blackburn and Blackwell, {Jenefer M.} and Leena Palotie and Anna Rautanen and {Australo-Anglo-Amer Spondyloarthri} and {Wellcome Trust Case Control Consor} and {Spondyloarthrit Res Consortium Can}",
year = "2011",
month = "8",
doi = "10.1038/ng.873",
language = "English",
volume = "43",
pages = "761--767",
journal = "Nature Genetics",
issn = "1061-4036",
publisher = "Nature Publishing Group",
number = "8",

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Evans, DM, Spencer, CCA, Pointon, JJ, Su, Z, Harvey, D, Kochan, G, Opperman, U, Dilthey, A, Pirinen, M, Stone, MA, Appleton, L, Moutsianis, L, Leslie, S, Wordsworth, T, Kenna, TJ, Karaderi, T, Thomas, GP, Ward, MM, Weisman, MH, Farrar, C, Bradbury, LA, Danoy, P, Inman, RD, Maksymowych, W, Gladman, D, Rahman, P, Morgan, A, Marzo-Ortega, H, Bowness, P, Gaffney, K, Gaston, JSH, Smith, M, Bruges-Armas, J, Couto, A-R, Sorrentino, R, Paladini, F, Ferreira, MA, Xu, H, Liu, Y, Jiang, L, Lopez-Larrea, C, Diaz-Pena, R, Lopez-Vazquez, A, Zayats, T, Band, G, Bellenguez, C, Blackburn, H, Blackwell, JM, Palotie, L, Rautanen, A, Australo-Anglo-Amer Spondyloarthri, Wellcome Trust Case Control Consor & Spondyloarthrit Res Consortium Can 2011, 'Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility', Nature Genetics, vol. 43, no. 8, pp. 761-767. https://doi.org/10.1038/ng.873

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. / Evans, David M.; Spencer, Chris C. A.; Pointon, Jennifer J.; Su, Zhan; Harvey, David; Kochan, Grazyna; Opperman, Udo; Dilthey, Alexander; Pirinen, Matti; Stone, Millicent A.; Appleton, Louise; Moutsianis, Loukas; Leslie, Stephen; Wordsworth, Tom; Kenna, Tony J.; Karaderi, Tugce; Thomas, Gethin P.; Ward, Michael M.; Weisman, Michael H.; Farrar, Claire; Bradbury, Linda A.; Danoy, Patrick; Inman, Robert D.; Maksymowych, Walter; Gladman, Dafna; Rahman, Proton; Morgan, Ann; Marzo-Ortega, Helena; Bowness, Paul; Gaffney, Karl; Gaston, J. S. Hill; Smith, Malcolm; Bruges-Armas, Jacome; Couto, Ana-Rita; Sorrentino, Rosa; Paladini, Fabiana; Ferreira, Manuel A.; Xu, Huji; Liu, Yu; Jiang, Lei; Lopez-Larrea, Carlos; Diaz-Pena, Roberto; Lopez-Vazquez, Antonio; Zayats, Tetyana; Band, Gavin; Bellenguez, Celine; Blackburn, Hannah; Blackwell, Jenefer M.; Palotie, Leena; Rautanen, Anna; Australo-Anglo-Amer Spondyloarthri; Wellcome Trust Case Control Consor; Spondyloarthrit Res Consortium Can.

In: Nature Genetics, Vol. 43, No. 8, 08.2011, p. 761-767.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

AU - Evans, David M.

AU - Spencer, Chris C. A.

AU - Pointon, Jennifer J.

AU - Su, Zhan

AU - Harvey, David

AU - Kochan, Grazyna

AU - Opperman, Udo

AU - Dilthey, Alexander

AU - Pirinen, Matti

AU - Stone, Millicent A.

AU - Appleton, Louise

AU - Moutsianis, Loukas

AU - Leslie, Stephen

AU - Wordsworth, Tom

AU - Kenna, Tony J.

AU - Karaderi, Tugce

AU - Thomas, Gethin P.

AU - Ward, Michael M.

AU - Weisman, Michael H.

AU - Farrar, Claire

AU - Bradbury, Linda A.

AU - Danoy, Patrick

AU - Inman, Robert D.

AU - Maksymowych, Walter

AU - Gladman, Dafna

AU - Rahman, Proton

AU - Morgan, Ann

AU - Marzo-Ortega, Helena

AU - Bowness, Paul

AU - Gaffney, Karl

AU - Gaston, J. S. Hill

AU - Smith, Malcolm

AU - Bruges-Armas, Jacome

AU - Couto, Ana-Rita

AU - Sorrentino, Rosa

AU - Paladini, Fabiana

AU - Ferreira, Manuel A.

AU - Xu, Huji

AU - Liu, Yu

AU - Jiang, Lei

AU - Lopez-Larrea, Carlos

AU - Diaz-Pena, Roberto

AU - Lopez-Vazquez, Antonio

AU - Zayats, Tetyana

AU - Band, Gavin

AU - Bellenguez, Celine

AU - Blackburn, Hannah

AU - Blackwell, Jenefer M.

AU - Palotie, Leena

AU - Rautanen, Anna

AU - Australo-Anglo-Amer Spondyloarthri

AU - Wellcome Trust Case Control Consor

AU - Spondyloarthrit Res Consortium Can

PY - 2011/8

Y1 - 2011/8

KW - GENOME-WIDE ASSOCIATION

KW - INFLAMMATORY-BOWEL-DISEASE

KW - GENETIC ASSOCIATION

KW - TRIMS PRECURSORS

KW - AMINOPEPTIDASE

KW - RISK

KW - HLA

KW - POPULATION

KW - PROMOTES

KW - CELLS

KW - 318 Medical biotechnology

KW - 1184 Genetics, developmental biology, physiology

U2 - 10.1038/ng.873

DO - 10.1038/ng.873

M3 - Article

VL - 43

SP - 761

EP - 767

JO - Nature Genetics

JF - Nature Genetics

SN - 1061-4036

IS - 8

ER -