Interleukin-4 repairs wear particle induced osteolysis by modulating macrophage polarization and bone turnover

Jukka Pajarinen; Tzuhua Lin; Akira Nabeshima; Taishi Sato; Emmanuel Gibon; Eemeli Jämsen; Tahsin N. Khan; Zhenyu Yao; Stuart B. Goodman

doi:10.1002/jbm.a.37142

Interleukin-4 repairs wear particle induced osteolysis by modulating macrophage polarization and bone turnover

Jukka Pajarinen, Tzuhua Lin, Akira Nabeshima, Taishi Sato, Emmanuel Gibon, Eemeli Jämsen, Tahsin N. Khan, Zhenyu Yao, Stuart B. Goodman

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Journal of Biomedical Materials Research. Part A
Volume	109
Issue number	8
Pages (from-to)	1512-1520
Number of pages	9
ISSN	1549-3296
DOIs	https://doi.org/10.1002/jbm.a.37142
Publication status	Published - 2021
MoE publication type	A1 Journal article-refereed

Fields of Science

interleukin&#8208
4
macrophage polarization
murine model
periprosthetic osteolysis
total joint replacement
NF-KAPPA-B
MESENCHYMAL STEM-CELLS
TOLL-LIKE RECEPTORS
IL-4 DELIVERY
JOINT REPLACEMENT
HUMAN OSTEOBLASTS
MURINE MODEL
OSTEOGENESIS
INHIBITION
OSTEOCLASTOGENESIS
3126 Surgery, anesthesiology, intensive care, radiology

Access to Document

10.1002/jbm.a.37142

Cite this

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title = "Interleukin-4 repairs wear particle induced osteolysis by modulating macrophage polarization and bone turnover",

keywords = "interleukin&#8208, 4, macrophage polarization, murine model, periprosthetic osteolysis, total joint replacement, NF-KAPPA-B, MESENCHYMAL STEM-CELLS, TOLL-LIKE RECEPTORS, IL-4 DELIVERY, JOINT REPLACEMENT, HUMAN OSTEOBLASTS, MURINE MODEL, OSTEOGENESIS, INHIBITION, OSTEOCLASTOGENESIS, 3126 Surgery, anesthesiology, intensive care, radiology",

author = "Jukka Pajarinen and Tzuhua Lin and Akira Nabeshima and Taishi Sato and Emmanuel Gibon and Eemeli J{\"a}msen and Khan, {Tahsin N.} and Zhenyu Yao and Goodman, {Stuart B.}",

year = "2021",

doi = "10.1002/jbm.a.37142",

language = "English",

volume = "109",

pages = "1512--1520",

journal = "Journal of Biomedical Materials Research. Part A",

issn = "1549-3296",

publisher = "John Wiley & Sons Ltd. ",

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TY - JOUR

T1 - Interleukin-4 repairs wear particle induced osteolysis by modulating macrophage polarization and bone turnover

AU - Pajarinen, Jukka

AU - Lin, Tzuhua

AU - Nabeshima, Akira

AU - Sato, Taishi

AU - Gibon, Emmanuel

AU - Jämsen, Eemeli

AU - Khan, Tahsin N.

AU - Yao, Zhenyu

AU - Goodman, Stuart B.

PY - 2021

Y1 - 2021

KW - interleukin&#8208

KW - 4

KW - macrophage polarization

KW - murine model

KW - periprosthetic osteolysis

KW - total joint replacement

KW - NF-KAPPA-B

KW - MESENCHYMAL STEM-CELLS

KW - TOLL-LIKE RECEPTORS

KW - IL-4 DELIVERY

KW - JOINT REPLACEMENT

KW - HUMAN OSTEOBLASTS

KW - MURINE MODEL

KW - OSTEOGENESIS

KW - INHIBITION

KW - OSTEOCLASTOGENESIS

KW - 3126 Surgery, anesthesiology, intensive care, radiology

U2 - 10.1002/jbm.a.37142

DO - 10.1002/jbm.a.37142

M3 - Article

SN - 1549-3296

VL - 109

SP - 1512

EP - 1520

JO - Journal of Biomedical Materials Research. Part A

JF - Journal of Biomedical Materials Research. Part A

IS - 8

ER -