Intraputamenal Cerebral Dopamine Neurotrophic Factor in Parkinson's Disease: A Randomized, Double-Blind, Multicenter Phase 1 Trial

Henri J. Huttunen; Sigrid Booms; Magnus Sjögren; Vera Kerstens; Jarkko Johansson; Rebecka Holmnas; Jani Koskinen; Natalia Kulesskaya; Patrik Fazio; Max Woolley; Alan Brady; Julia Williams; David Johnson; Narges Dailami; William Gray; Reeta Levo; Mart Saarma; Christer Halldin; Johan Marjamaa; Julio Resendiz-Nieves; Irena Grubor; Goran Lind; Johanna Eerola-Rautio; Tuomas Mertsalmi; Mattias Andreasson; Gesine Paul; Juha Rinne; Riku Kivisaari; Hjalmar Bjartmarz; Per Almqvist; Andrea Varrone; Filip Scheperjans; Hakan Widner; Per Svenningsson

doi:10.1002/mds.29426

Intraputamenal Cerebral Dopamine Neurotrophic Factor in Parkinson's Disease: A Randomized, Double-Blind, Multicenter Phase 1 Trial

Henri J. Huttunen, Sigrid Booms, Magnus Sjögren, Vera Kerstens, Jarkko Johansson, Rebecka Holmnas, Jani Koskinen, Natalia Kulesskaya, Patrik Fazio, Max Woolley, Alan Brady, Julia Williams, David Johnson, Narges Dailami, William Gray, Reeta Levo, Mart Saarma, Christer Halldin, Johan Marjamaa, Julio Resendiz-NievesIrena Grubor, Goran Lind, Johanna Eerola-Rautio, Tuomas Mertsalmi, Mattias Andreasson, Gesine Paul, Juha Rinne, Riku Kivisaari, Hjalmar Bjartmarz, Per Almqvist, Andrea Varrone, Filip Scheperjans, Hakan Widner, Per Svenningsson

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Movement Disorders
Volume	38
Issue number	7
Pages (from-to)	1209-1222
Number of pages	14
ISSN	0885-3185
DOIs	https://doi.org/10.1002/mds.29426
Publication status	Published - Jul 2023
MoE publication type	A1 Journal article-refereed

Fields of Science

3112 Neurosciences
3124 Neurology and psychiatry

Access to Document

10.1002/mds.29426

Movement Disorders - 2023 - HuttunenFinal published version, 1.07 MBLicence: CC BY-NC-ND

Cite this

Huttunen, H. J., Booms, S., Sjögren, M., Kerstens, V., Johansson, J., Holmnas, R., Koskinen, J., Kulesskaya, N., Fazio, P., Woolley, M., Brady, A., Williams, J., Johnson, D., Dailami, N., Gray, W., Levo, R., Saarma, M., Halldin, C., Marjamaa, J., ... Svenningsson, P. (2023). Intraputamenal Cerebral Dopamine Neurotrophic Factor in Parkinson's Disease: A Randomized, Double-Blind, Multicenter Phase 1 Trial. Movement Disorders, 38(7), 1209-1222. https://doi.org/10.1002/mds.29426

@article{09924c086e4f491ca7a9bb4de776bb2f,

title = "Intraputamenal Cerebral Dopamine Neurotrophic Factor in Parkinson's Disease: A Randomized, Double-Blind, Multicenter Phase 1 Trial",

keywords = "Clinical trial, Convection-enhanced delivery, Movement disorder, Neurotrophic factor, Synucleinopathy, Transcutaneous port, 3112 Neurosciences, 3124 Neurology and psychiatry",

author = "Huttunen, {Henri J.} and Sigrid Booms and Magnus Sj{\"o}gren and Vera Kerstens and Jarkko Johansson and Rebecka Holmnas and Jani Koskinen and Natalia Kulesskaya and Patrik Fazio and Max Woolley and Alan Brady and Julia Williams and David Johnson and Narges Dailami and William Gray and Reeta Levo and Mart Saarma and Christer Halldin and Johan Marjamaa and Julio Resendiz-Nieves and Irena Grubor and Goran Lind and Johanna Eerola-Rautio and Tuomas Mertsalmi and Mattias Andreasson and Gesine Paul and Juha Rinne and Riku Kivisaari and Hjalmar Bjartmarz and Per Almqvist and Andrea Varrone and Filip Scheperjans and Hakan Widner and Per Svenningsson",

year = "2023",

month = jul,

doi = "10.1002/mds.29426",

language = "English",

volume = "38",

pages = "1209--1222",

journal = "Movement Disorders",

issn = "0885-3185",

publisher = "Wiley",

number = "7",

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Huttunen, HJ, Booms, S, Sjögren, M, Kerstens, V, Johansson, J, Holmnas, R, Koskinen, J, Kulesskaya, N, Fazio, P, Woolley, M, Brady, A, Williams, J, Johnson, D, Dailami, N, Gray, W, Levo, R , Saarma, M, Halldin, C, Marjamaa, J , Resendiz-Nieves, J, Grubor, I, Lind, G, Eerola-Rautio, J , Mertsalmi, T, Andreasson, M, Paul, G, Rinne, J, Kivisaari, R, Bjartmarz, H, Almqvist, P, Varrone, A, Scheperjans, F, Widner, H & Svenningsson, P 2023, 'Intraputamenal Cerebral Dopamine Neurotrophic Factor in Parkinson's Disease: A Randomized, Double-Blind, Multicenter Phase 1 Trial', Movement Disorders, vol. 38, no. 7, pp. 1209-1222. https://doi.org/10.1002/mds.29426

TY - JOUR

T1 - Intraputamenal Cerebral Dopamine Neurotrophic Factor in Parkinson's Disease

T2 - A Randomized, Double-Blind, Multicenter Phase 1 Trial

AU - Huttunen, Henri J.

AU - Booms, Sigrid

AU - Sjögren, Magnus

AU - Kerstens, Vera

AU - Johansson, Jarkko

AU - Holmnas, Rebecka

AU - Koskinen, Jani

AU - Kulesskaya, Natalia

AU - Fazio, Patrik

AU - Woolley, Max

AU - Brady, Alan

AU - Williams, Julia

AU - Johnson, David

AU - Dailami, Narges

AU - Gray, William

AU - Levo, Reeta

AU - Saarma, Mart

AU - Halldin, Christer

AU - Marjamaa, Johan

AU - Resendiz-Nieves, Julio

AU - Grubor, Irena

AU - Lind, Goran

AU - Eerola-Rautio, Johanna

AU - Mertsalmi, Tuomas

AU - Andreasson, Mattias

AU - Paul, Gesine

AU - Rinne, Juha

AU - Kivisaari, Riku

AU - Bjartmarz, Hjalmar

AU - Almqvist, Per

AU - Varrone, Andrea

AU - Scheperjans, Filip

AU - Widner, Hakan

AU - Svenningsson, Per

PY - 2023/7

Y1 - 2023/7

KW - Clinical trial

KW - Convection-enhanced delivery

KW - Movement disorder

KW - Neurotrophic factor

KW - Synucleinopathy

KW - Transcutaneous port

KW - 3112 Neurosciences

KW - 3124 Neurology and psychiatry

U2 - 10.1002/mds.29426

DO - 10.1002/mds.29426

M3 - Article

C2 - 37212361

SN - 0885-3185

VL - 38

SP - 1209

EP - 1222

JO - Movement Disorders

JF - Movement Disorders

IS - 7

ER -