Intravenous Delivery of Hydrophobin-Functionalized Porous Silicon Nanoparticles: Stability, Plasma Protein Adsorption and Biodistribution

Mirkka Sarparanta; Luis M. Bimbo; Jussi Rytkönen; Ermei Mäkilä; Timo J. Laaksonen; Päivi Laaksonen; Markus Nyman; Jarno Salonen; Markus B. Linder; Jouni Hirvonen; Hélder A. Santos; Anu J. Airaksinen

doi:10.1021/mp200611d

Intravenous Delivery of Hydrophobin-Functionalized Porous Silicon Nanoparticles: Stability, Plasma Protein Adsorption and Biodistribution

Mirkka Sarparanta, Luis M. Bimbo, Jussi Rytkönen, Ermei Mäkilä, Timo J. Laaksonen, Päivi Laaksonen, Markus Nyman, Jarno Salonen, Markus B. Linder, Jouni Hirvonen, Hélder A. Santos, Anu J. Airaksinen

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Molecular Pharmaceutics
Volume	9
Issue number	3
Pages (from-to)	654-663
Number of pages	10
ISSN	1543-8384
DOIs	https://doi.org/10.1021/mp200611d
Publication status	Published - 25 Jan 2012
MoE publication type	A1 Journal article-refereed

Fields of Science

porous silicon
hydrophobin
nanoparticle
protein adsorption
biodistribution
MESOPOROUS SILICON
DRUG-DELIVERY
IN-VIVO
MICROPARTICLES
SURFACE
PARTICLES
CLEARANCE
KINETICS
BLOOD
MODEL
116 Chemical sciences

Access to Document

10.1021/mp200611d

Cite this

Sarparanta, M., Bimbo, L. M., Rytkönen, J., Mäkilä, E., Laaksonen, T. J., Laaksonen, P., Nyman, M., Salonen, J., Linder, M. B., Hirvonen, J., Santos, H. A., & Airaksinen, A. J. (2012). Intravenous Delivery of Hydrophobin-Functionalized Porous Silicon Nanoparticles: Stability, Plasma Protein Adsorption and Biodistribution. Molecular Pharmaceutics, 9(3), 654-663. https://doi.org/10.1021/mp200611d

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title = "Intravenous Delivery of Hydrophobin-Functionalized Porous Silicon Nanoparticles: Stability, Plasma Protein Adsorption and Biodistribution",

keywords = "porous silicon, hydrophobin, nanoparticle, protein adsorption, biodistribution, MESOPOROUS SILICON, DRUG-DELIVERY, IN-VIVO, MICROPARTICLES, SURFACE, PARTICLES, CLEARANCE, KINETICS, BLOOD, MODEL, 116 Chemical sciences",

author = "Mirkka Sarparanta and Bimbo, {Luis M.} and Jussi Rytk{\"o}nen and Ermei M{\"a}kil{\"a} and Laaksonen, {Timo J.} and P{\"a}ivi Laaksonen and Markus Nyman and Jarno Salonen and Linder, {Markus B.} and Jouni Hirvonen and Santos, {H{\'e}lder A.} and Airaksinen, {Anu J.}",

year = "2012",

month = jan,

day = "25",

doi = "10.1021/mp200611d",

language = "English",

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pages = "654--663",

journal = "Molecular Pharmaceutics",

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publisher = "American Chemical Society",

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Sarparanta, M , Bimbo, LM, Rytkönen, J, Mäkilä, E, Laaksonen, TJ, Laaksonen, P, Nyman, M, Salonen, J, Linder, MB, Hirvonen, J , Santos, HA & Airaksinen, AJ 2012, 'Intravenous Delivery of Hydrophobin-Functionalized Porous Silicon Nanoparticles: Stability, Plasma Protein Adsorption and Biodistribution', Molecular Pharmaceutics, vol. 9, no. 3, pp. 654-663. https://doi.org/10.1021/mp200611d

TY - JOUR

T1 - Intravenous Delivery of Hydrophobin-Functionalized Porous Silicon Nanoparticles: Stability, Plasma Protein Adsorption and Biodistribution

AU - Sarparanta, Mirkka

AU - Bimbo, Luis M.

AU - Rytkönen, Jussi

AU - Mäkilä, Ermei

AU - Laaksonen, Timo J.

AU - Laaksonen, Päivi

AU - Nyman, Markus

AU - Salonen, Jarno

AU - Linder, Markus B.

AU - Hirvonen, Jouni

AU - Santos, Hélder A.

AU - Airaksinen, Anu J.

PY - 2012/1/25

Y1 - 2012/1/25

KW - porous silicon

KW - hydrophobin

KW - nanoparticle

KW - protein adsorption

KW - biodistribution

KW - MESOPOROUS SILICON

KW - DRUG-DELIVERY

KW - IN-VIVO

KW - MICROPARTICLES

KW - SURFACE

KW - PARTICLES

KW - CLEARANCE

KW - KINETICS

KW - BLOOD

KW - MODEL

KW - 116 Chemical sciences

U2 - 10.1021/mp200611d

DO - 10.1021/mp200611d

M3 - Article

SN - 1543-8384

VL - 9

SP - 654

EP - 663

JO - Molecular Pharmaceutics

JF - Molecular Pharmaceutics

IS - 3

ER -