IR spectroscopy together with multivariate data analysis as a process analytical tool for in-line monitoring of crystallization process and solid-state analysis of crystalline product

K Pöllänen; A Häkkinen; SP Reinikainen; J Rantanen; M Karjalainen; M Louhi-Kultanen; L Nyström

doi:10.1016/j.jpba.2005.01.009

IR spectroscopy together with multivariate data analysis as a process analytical tool for in-line monitoring of crystallization process and solid-state analysis of crystalline product

K Pöllänen
, A Häkkinen
, SP Reinikainen
, J Rantanen
, M Karjalainen
, M Louhi-Kultanen
, L Nyström

Faculty of Pharmacy

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Journal of Pharmaceutical and Biomedical Analysis
Volume	38
Issue number	2
Pages (from-to)	275-284
Number of pages	10
ISSN	0731-7085
DOIs	https://doi.org/10.1016/j.jpba.2005.01.009
Publication status	Published - 2005
MoE publication type	A1 Journal article-refereed

Fields of Science

controlled crystallization
in situ process monitoring
multivariate analysis
diffuse reflectance infra red spectroscopy
attenuated total reflection infra red spectroscopy
ORTHOGONAL SIGNAL CORRECTION
TRANSFORM INFRARED-SPECTROSCOPY
ATR-FTIR
POLYMORPHS
ACID
SOLVENT
SITU
PLS
317 Pharmacy

Access to Document

10.1016/j.jpba.2005.01.009

Cite this

Pöllänen, K., Häkkinen, A., Reinikainen, SP., Rantanen, J., Karjalainen, M., Louhi-Kultanen, M., & Nyström, L. (2005). IR spectroscopy together with multivariate data analysis as a process analytical tool for in-line monitoring of crystallization process and solid-state analysis of crystalline product. Journal of Pharmaceutical and Biomedical Analysis, 38(2), 275-284. https://doi.org/10.1016/j.jpba.2005.01.009

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title = "IR spectroscopy together with multivariate data analysis as a process analytical tool for in-line monitoring of crystallization process and solid-state analysis of crystalline product",

keywords = "controlled crystallization, in situ process monitoring, multivariate analysis, diffuse reflectance infra red spectroscopy, attenuated total reflection infra red spectroscopy, ORTHOGONAL SIGNAL CORRECTION, TRANSFORM INFRARED-SPECTROSCOPY, ATR-FTIR, POLYMORPHS, ACID, SOLVENT, SITU, PLS, 317 Pharmacy",

author = "K P{\"o}ll{\"a}nen and A H{\"a}kkinen and SP Reinikainen and J Rantanen and M Karjalainen and M Louhi-Kultanen and L Nystr{\"o}m",

year = "2005",

doi = "10.1016/j.jpba.2005.01.009",

language = "English",

volume = "38",

pages = "275--284",

journal = "Journal of Pharmaceutical and Biomedical Analysis",

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publisher = "Elsevier B.V.",

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}

Pöllänen, K, Häkkinen, A, Reinikainen, SP, Rantanen, J, Karjalainen, M, Louhi-Kultanen, M & Nyström, L 2005, 'IR spectroscopy together with multivariate data analysis as a process analytical tool for in-line monitoring of crystallization process and solid-state analysis of crystalline product', Journal of Pharmaceutical and Biomedical Analysis, vol. 38, no. 2, pp. 275-284. https://doi.org/10.1016/j.jpba.2005.01.009

IR spectroscopy together with multivariate data analysis as a process analytical tool for in-line monitoring of crystallization process and solid-state analysis of crystalline product. / Pöllänen, K; Häkkinen, A; Reinikainen, SP et al.
In: Journal of Pharmaceutical and Biomedical Analysis, Vol. 38, No. 2, 2005, p. 275-284.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - IR spectroscopy together with multivariate data analysis as a process analytical tool for in-line monitoring of crystallization process and solid-state analysis of crystalline product

AU - Pöllänen, K

AU - Häkkinen, A

AU - Reinikainen, SP

AU - Rantanen, J

AU - Karjalainen, M

AU - Louhi-Kultanen, M

AU - Nyström, L

PY - 2005

Y1 - 2005

KW - controlled crystallization

KW - in situ process monitoring

KW - multivariate analysis

KW - diffuse reflectance infra red spectroscopy

KW - attenuated total reflection infra red spectroscopy

KW - ORTHOGONAL SIGNAL CORRECTION

KW - TRANSFORM INFRARED-SPECTROSCOPY

KW - ATR-FTIR

KW - POLYMORPHS

KW - ACID

KW - SOLVENT

KW - SITU

KW - PLS

KW - 317 Pharmacy

U2 - 10.1016/j.jpba.2005.01.009

DO - 10.1016/j.jpba.2005.01.009

M3 - Article

SN - 0731-7085

VL - 38

SP - 275

EP - 284

JO - Journal of Pharmaceutical and Biomedical Analysis

JF - Journal of Pharmaceutical and Biomedical Analysis

IS - 2

ER -

Pöllänen K, Häkkinen A, Reinikainen SP, Rantanen J, Karjalainen M, Louhi-Kultanen M et al. IR spectroscopy together with multivariate data analysis as a process analytical tool for in-line monitoring of crystallization process and solid-state analysis of crystalline product. Journal of Pharmaceutical and Biomedical Analysis. 2005;38(2):275-284. doi: 10.1016/j.jpba.2005.01.009