Ketamine and norketamine attenuate oxycodone tolerance markedly less than that of morphine

from behaviour to drug availability

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalBritish Journal of Anaesthesia
Volume120
Issue number4
Pages (from-to)818-826
Number of pages9
ISSN0007-0912
DOIs
Publication statusPublished - Apr 2018
MoE publication typeA1 Journal article-refereed

Fields of Science

  • anaesthetics
  • dissociative
  • analgesics
  • opioid
  • ketamine
  • morphine
  • oxycodone
  • pain
  • tolerance
  • NMDA RECEPTOR ANTAGONIST
  • ANTINOCICEPTIVE TOLERANCE
  • HEALTHY-VOLUNTEERS
  • PERSISTENT PAIN
  • RODENT MODELS
  • INHIBITION
  • RAT
  • GLUCURONIDATION
  • DEPENDENCE
  • PHARMACOKINETICS
  • 3126 Surgery, anesthesiology, intensive care, radiology

Cite this

@article{edcab8026ddf4c8b93f1c66dda536d03,
title = "Ketamine and norketamine attenuate oxycodone tolerance markedly less than that of morphine: from behaviour to drug availability",
keywords = "anaesthetics, dissociative, analgesics, opioid, ketamine, morphine, oxycodone, pain, tolerance, NMDA RECEPTOR ANTAGONIST, ANTINOCICEPTIVE TOLERANCE, HEALTHY-VOLUNTEERS, PERSISTENT PAIN, RODENT MODELS, INHIBITION, RAT, GLUCURONIDATION, DEPENDENCE, PHARMACOKINETICS, 3126 Surgery, anesthesiology, intensive care, radiology",
author = "T. Lilius and E. Kangas and M. Niemi and P. Rauhala and E. Kalso",
year = "2018",
month = "4",
doi = "10.1016/j.bja.2017.11.081",
language = "English",
volume = "120",
pages = "818--826",
journal = "British Journal of Anaesthesia",
issn = "0007-0912",
publisher = "ELSEVIER SCI IRELAND LTD",
number = "4",

}

Ketamine and norketamine attenuate oxycodone tolerance markedly less than that of morphine : from behaviour to drug availability. / Lilius, T.; Kangas, E.; Niemi, M.; Rauhala, P.; Kalso, E.

In: British Journal of Anaesthesia, Vol. 120, No. 4, 04.2018, p. 818-826.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Ketamine and norketamine attenuate oxycodone tolerance markedly less than that of morphine

T2 - from behaviour to drug availability

AU - Lilius, T.

AU - Kangas, E.

AU - Niemi, M.

AU - Rauhala, P.

AU - Kalso, E.

PY - 2018/4

Y1 - 2018/4

KW - anaesthetics

KW - dissociative

KW - analgesics

KW - opioid

KW - ketamine

KW - morphine

KW - oxycodone

KW - pain

KW - tolerance

KW - NMDA RECEPTOR ANTAGONIST

KW - ANTINOCICEPTIVE TOLERANCE

KW - HEALTHY-VOLUNTEERS

KW - PERSISTENT PAIN

KW - RODENT MODELS

KW - INHIBITION

KW - RAT

KW - GLUCURONIDATION

KW - DEPENDENCE

KW - PHARMACOKINETICS

KW - 3126 Surgery, anesthesiology, intensive care, radiology

U2 - 10.1016/j.bja.2017.11.081

DO - 10.1016/j.bja.2017.11.081

M3 - Article

VL - 120

SP - 818

EP - 826

JO - British Journal of Anaesthesia

JF - British Journal of Anaesthesia

SN - 0007-0912

IS - 4

ER -