Ketamine coadministration attenuates morphine tolerance and leads to increased brain concentrations of both drugs in the rat

Tuomas Lilius, V. Jokinen, M. S. Neuvonen, Mikko Niemi, E. A. Kalso, P. V. Rauhala

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalBritish Journal of Pharmacology
Volume172
Issue number11
Pages (from-to)2799-2813
Number of pages15
ISSN0007-1188
DOIs
Publication statusPublished - Jun 2015
MoE publication typeA1 Journal article-refereed

Fields of Science

  • EVIDENCE-BASED RECOMMENDATIONS
  • NMDA RECEPTOR ANTAGONIST
  • P-GLYCOPROTEIN
  • CANCER PAIN
  • IN-VITRO
  • UDP-GLUCURONOSYLTRANSFERASES
  • NORKETAMINE ENANTIOMERS
  • SUBCUTANEOUS KETAMINE
  • PASSIVE PERMEABILITY
  • ARRIVE GUIDELINES
  • 317 Pharmacy

Cite this

@article{629e8f26c60047e1a6ea800b8977fbad,
title = "Ketamine coadministration attenuates morphine tolerance and leads to increased brain concentrations of both drugs in the rat",
keywords = "EVIDENCE-BASED RECOMMENDATIONS, NMDA RECEPTOR ANTAGONIST, P-GLYCOPROTEIN, CANCER PAIN, IN-VITRO, UDP-GLUCURONOSYLTRANSFERASES, NORKETAMINE ENANTIOMERS, SUBCUTANEOUS KETAMINE, PASSIVE PERMEABILITY, ARRIVE GUIDELINES, 317 Pharmacy",
author = "Tuomas Lilius and V. Jokinen and Neuvonen, {M. S.} and Mikko Niemi and Kalso, {E. A.} and Rauhala, {P. V.}",
year = "2015",
month = "6",
doi = "10.1111/bph.12974",
language = "English",
volume = "172",
pages = "2799--2813",
journal = "British Journal of Pharmacology",
issn = "0007-1188",
publisher = "Wiley",
number = "11",

}

Ketamine coadministration attenuates morphine tolerance and leads to increased brain concentrations of both drugs in the rat. / Lilius, Tuomas; Jokinen, V.; Neuvonen, M. S.; Niemi, Mikko; Kalso, E. A.; Rauhala, P. V.

In: British Journal of Pharmacology, Vol. 172, No. 11, 06.2015, p. 2799-2813.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Ketamine coadministration attenuates morphine tolerance and leads to increased brain concentrations of both drugs in the rat

AU - Lilius, Tuomas

AU - Jokinen, V.

AU - Neuvonen, M. S.

AU - Niemi, Mikko

AU - Kalso, E. A.

AU - Rauhala, P. V.

PY - 2015/6

Y1 - 2015/6

KW - EVIDENCE-BASED RECOMMENDATIONS

KW - NMDA RECEPTOR ANTAGONIST

KW - P-GLYCOPROTEIN

KW - CANCER PAIN

KW - IN-VITRO

KW - UDP-GLUCURONOSYLTRANSFERASES

KW - NORKETAMINE ENANTIOMERS

KW - SUBCUTANEOUS KETAMINE

KW - PASSIVE PERMEABILITY

KW - ARRIVE GUIDELINES

KW - 317 Pharmacy

U2 - 10.1111/bph.12974

DO - 10.1111/bph.12974

M3 - Article

VL - 172

SP - 2799

EP - 2813

JO - British Journal of Pharmacology

JF - British Journal of Pharmacology

SN - 0007-1188

IS - 11

ER -