Lactate-Induced Glucose Output Is Unchanged by Metformin at a Therapeutic Concentration - A Mass Spectrometry Imaging Study of the Perfused Rat Liver

Giulio Calza, Elisabeth Nyberg, Matias Mäkinen, Rabah Soliymani, Annunziata Cascone, Dan Lindholm, Emanuele Barborini, Marc Baumann, Maciej Lalowski, Ove Eriksson

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
Article number141
JournalFrontiers in Pharmacology
Volume9
Number of pages12
ISSN1663-9812
DOIs
Publication statusPublished - 22 Feb 2018
MoE publication typeA1 Journal article-refereed

Fields of Science

  • metformin
  • diabetes
  • mass spectrometry imaging
  • liver
  • gluconeogenesis
  • lactate
  • DIABETES-MELLITUS
  • RESPIRATORY-CHAIN
  • CANCER
  • MECHANISM
  • NIDDM
  • RISK
  • METABOLISM
  • BIGUANIDES
  • GLUCONEOGENESIS
  • INHIBITION
  • 317 Pharmacy
  • 3121 Internal medicine

Cite this

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title = "Lactate-Induced Glucose Output Is Unchanged by Metformin at a Therapeutic Concentration - A Mass Spectrometry Imaging Study of the Perfused Rat Liver",
keywords = "metformin, diabetes, mass spectrometry imaging, liver, gluconeogenesis, lactate, DIABETES-MELLITUS, RESPIRATORY-CHAIN, CANCER, MECHANISM, NIDDM, RISK, METABOLISM, BIGUANIDES, GLUCONEOGENESIS, INHIBITION, 317 Pharmacy, 3121 Internal medicine",
author = "Giulio Calza and Elisabeth Nyberg and Matias M{\"a}kinen and Rabah Soliymani and Annunziata Cascone and Dan Lindholm and Emanuele Barborini and Marc Baumann and Maciej Lalowski and Ove Eriksson",
year = "2018",
month = "2",
day = "22",
doi = "10.3389/fphar.2018.00141",
language = "English",
volume = "9",
journal = "Frontiers in Pharmacology",
issn = "1663-9812",
publisher = "Frontiers Media",

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TY - JOUR

T1 - Lactate-Induced Glucose Output Is Unchanged by Metformin at a Therapeutic Concentration - A Mass Spectrometry Imaging Study of the Perfused Rat Liver

AU - Calza, Giulio

AU - Nyberg, Elisabeth

AU - Mäkinen, Matias

AU - Soliymani, Rabah

AU - Cascone, Annunziata

AU - Lindholm, Dan

AU - Barborini, Emanuele

AU - Baumann, Marc

AU - Lalowski, Maciej

AU - Eriksson, Ove

PY - 2018/2/22

Y1 - 2018/2/22

KW - metformin

KW - diabetes

KW - mass spectrometry imaging

KW - liver

KW - gluconeogenesis

KW - lactate

KW - DIABETES-MELLITUS

KW - RESPIRATORY-CHAIN

KW - CANCER

KW - MECHANISM

KW - NIDDM

KW - RISK

KW - METABOLISM

KW - BIGUANIDES

KW - GLUCONEOGENESIS

KW - INHIBITION

KW - 317 Pharmacy

KW - 3121 Internal medicine

U2 - 10.3389/fphar.2018.00141

DO - 10.3389/fphar.2018.00141

M3 - Article

VL - 9

JO - Frontiers in Pharmacology

JF - Frontiers in Pharmacology

SN - 1663-9812

M1 - 141

ER -