Lactose utilisation to furan carboxylates: a unique source for platform molecules

Joseph Install, Anže Zupanc, Mikko Nikunen, Janne Jänis, Timo Repo

Research output: Contribution to journalArticleScientificpeer-review


A highly efficient utilisation of lactose, a widely produced side-stream product to produce furancarboxylates in two steps, is presented. Firstly an enhanced nitric acid oxidation of lactose with Fe(NO3)3 to achieve a 75% yield of mucic acid was developed. Mucic acid was then quantitatively dehydrated to produce dibutyl-2,5-furandicarboxylate and butyl-2-furancarboxylate (66.6% and 33.1% respectively) using phosphotungstic acid catalyst in 1-butanol as a reaction solvent. The overall process presents and excellent carbon utilisation efficiency of 49.9 mol%.

Original languageEnglish
JournalGreen Chemistry
Issue number3
Pages (from-to)1381-1386
Number of pages6
Publication statusPublished - 2024
MoE publication typeA1 Journal article-refereed

Fields of Science

  • 116 Chemical sciences

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