Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

M. Carola Zillikens, Serkalem Demissie, Yi-Hsiang Hsu, Laura M. Yerges-Armstrong, Wen-Chi Chou, Lisette Stolk, Gregory Livshits, Linda Broer, Toby Johnson, Daniel L. Koller, Zoltyn Kutalik, Jian'an Luan, Ida Malkin, Janina S. Ried, Albert V. Smith, Gudmar Thorleifsson, Liesbeth Vandenput, Jing Hua Zhao, Weihua Zhang, Ali Aghdassi & 173 others Kristina Akesson, Najaf Amin, Leslie J. Baier, Ines Barroso, David A. Bennett, Lars Bertram, Rainer Biffar, Murielle Bochud, Michael Boehnke, Ingrid B. Borecki, Aron S. Buchman, Liisa Byberg, Harry Campbell, Natalia Campos Obanda, Jane A. Cauley, Peggy M. Cawthon, Henna Cederberg, Zhao Chen, Nam H. Cho, Hyung Jin Choi, Melina Claussnitzer, Francis Collins, Steven R. Cummings, Philip L. De Jager, Ilja Demuth, Rosalie A. M. Dhonukshe-Rutten, Luda Diatchenko, Gudny Eiriksdottir, Anke W. Enneman, Mike Erdos, Johan G. Eriksson, Joel Eriksson, Karol Estrada, Daniel S. Evans, Mary F. Feitosa, Mao Fu, Melissa Garcia, Christian Gieger, Thomas Girke, Nicole L. Glazer, Harald Grallert, Jagvir Grewal, Bok-Ghee Han, Robert L. Hanson, Caroline Hayward, Albert Hofman, Eric P. Hoffman, Georg Homuth, Wen-Chi Hsueh, Monica J. Hubal, Alan Hubbard, Kim M. Huffman, Lise B. Husted, Thomas Illig, Erik Ingelsson, Till Ittermann, John-Olov Jansson, Joanne M. Jordan, Antti Jula, Magnus Karlsson, Kay-Tee Khaw, Tuomas O. Kilpainen, Norman Klopp, Jacqueline S. L. Kloth, Heikki A. Koistinen, William E. Kraus, Stephen Kritchevsky, Teemu Kuulasmaa, Johanna Kuusisto, Markku Laakso, Jari Lahti, Thomas Lang, Bente L. Langdahl, Lenore J. Launer, Jong-Young Lee, Markus M. Lerch, Joshua R. Lewis, Lars Lind, Cecilia Lindgren, Yongmei Liu, Tian Liu, Youfang Liu, Osten Ljunggren, Mattias Lorentzon, Robert N. Luben, William Maixner, Fiona E. McGuigan, Carolina Medina-Gomez, Thomas Meitinger, Hakan Melhus, Dan Mellstrom, Simon Melov, Karl Michaelsson, Braxton D. Mitchell, Andrew P. Morris, Leif Mosekilde, Anne Newman, Carrie M. Nielson, Jeffrey R. O'Connell, Ben A. Oostra, Eric S. Orwoll, Aarno Palotie, Stephen C. J. Parker, Munro Peacock, Markus Perola, Annette Peters, Ozren Polasek, Richard L. Prince, Katri Raikkonen, Stuart H. Ralston, Samuli Ripatti, John A. Robbins, Jerome I. Rotter, Igor Rudan, Veikko Salomaa, Suzanne Satterfield, Eric E. Schadt, Sabine Schipf, Laura Scott, Joban Sehmi, Jian Shen, Chan Soo Shin, Gunnar Sigurdsson, Shad Smith, Nicole Soranzo, Alena Stancakova, Elisabeth Steinhagen-Thiessen, Elizabeth A. Streeten, Unnur Styrkarsdottir, Karin M. A. Swart, Sian-Tsung Tan, Mark A. Tarnopolsky, Patricia Thompson, Cynthia A. Thomson, Unnur Thorsteinsdottir, Emmi Tikkanen, Gregory J. Tranah, Jaakko Tuomilehto, Natasja M. van Schoor, Arjun Verma, Peter Vollenweider, Henry Voelzke, Jean Wactawski-Wende, Mark Walker, Michael N. Weedon, Ryan Welch, H. -Erich Wichmann, Elisabeth Widen, Frances M. K. Williams, James F. Wilson, Nicole C. Wright, Weijia Xie, Lei Yu, Yanhua Zhou, John C. Chambers, Angela Doring, Cornelia M. van Duijn, Michael J. Econs, Vilmundur Gudnason, Jaspal S. Kooner, Bruce M. Psaty, Timothy D. Spector, Kari Stefansson, Fernando Rivadeneira, Andre G. Uitterlinden, Nicholas J. Wareham, Vicky Ossowski, Dawn Waterworth, Ruth J. F. Loos, David Karasik, Tamara B. Harris, Claes Ohlsson, Douglas P. Kiel

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
Article number80
JournalNature Communications
Volume8
Number of pages13
ISSN2041-1723
DOIs
Publication statusPublished - 19 Jul 2017
MoE publication typeA1 Journal article-refereed

Fields of Science

  • SKELETAL-MUSCLE MASS
  • BONE-MINERAL DENSITY
  • PHYSICAL-DISABILITY
  • INSULIN-RESISTANCE
  • GENE-EXPRESSION
  • UNITED-STATES
  • HUMAN HEIGHT
  • VARIANTS
  • OBESITY
  • SARCOPENIA
  • 3121 Internal medicine

Cite this

Zillikens, M. C., Demissie, S., Hsu, Y-H., Yerges-Armstrong, L. M., Chou, W-C., Stolk, L., ... Kiel, D. P. (2017). Large meta-analysis of genome-wide association studies identifies five loci for lean body mass. Nature Communications, 8, [80]. https://doi.org/10.1038/s41467-017-00031-7
Zillikens, M. Carola ; Demissie, Serkalem ; Hsu, Yi-Hsiang ; Yerges-Armstrong, Laura M. ; Chou, Wen-Chi ; Stolk, Lisette ; Livshits, Gregory ; Broer, Linda ; Johnson, Toby ; Koller, Daniel L. ; Kutalik, Zoltyn ; Luan, Jian'an ; Malkin, Ida ; Ried, Janina S. ; Smith, Albert V. ; Thorleifsson, Gudmar ; Vandenput, Liesbeth ; Zhao, Jing Hua ; Zhang, Weihua ; Aghdassi, Ali ; Akesson, Kristina ; Amin, Najaf ; Baier, Leslie J. ; Barroso, Ines ; Bennett, David A. ; Bertram, Lars ; Biffar, Rainer ; Bochud, Murielle ; Boehnke, Michael ; Borecki, Ingrid B. ; Buchman, Aron S. ; Byberg, Liisa ; Campbell, Harry ; Obanda, Natalia Campos ; Cauley, Jane A. ; Cawthon, Peggy M. ; Cederberg, Henna ; Chen, Zhao ; Cho, Nam H. ; Choi, Hyung Jin ; Claussnitzer, Melina ; Collins, Francis ; Cummings, Steven R. ; De Jager, Philip L. ; Demuth, Ilja ; Dhonukshe-Rutten, Rosalie A. M. ; Diatchenko, Luda ; Eiriksdottir, Gudny ; Enneman, Anke W. ; Erdos, Mike ; Eriksson, Johan G. ; Eriksson, Joel ; Estrada, Karol ; Evans, Daniel S. ; Feitosa, Mary F. ; Fu, Mao ; Garcia, Melissa ; Gieger, Christian ; Girke, Thomas ; Glazer, Nicole L. ; Grallert, Harald ; Grewal, Jagvir ; Han, Bok-Ghee ; Hanson, Robert L. ; Hayward, Caroline ; Hofman, Albert ; Hoffman, Eric P. ; Homuth, Georg ; Hsueh, Wen-Chi ; Hubal, Monica J. ; Hubbard, Alan ; Huffman, Kim M. ; Husted, Lise B. ; Illig, Thomas ; Ingelsson, Erik ; Ittermann, Till ; Jansson, John-Olov ; Jordan, Joanne M. ; Jula, Antti ; Karlsson, Magnus ; Khaw, Kay-Tee ; Kilpainen, Tuomas O. ; Klopp, Norman ; Kloth, Jacqueline S. L. ; Koistinen, Heikki A. ; Kraus, William E. ; Kritchevsky, Stephen ; Kuulasmaa, Teemu ; Kuusisto, Johanna ; Laakso, Markku ; Lahti, Jari ; Lang, Thomas ; Langdahl, Bente L. ; Launer, Lenore J. ; Lee, Jong-Young ; Lerch, Markus M. ; Lewis, Joshua R. ; Lind, Lars ; Lindgren, Cecilia ; Liu, Yongmei ; Liu, Tian ; Liu, Youfang ; Ljunggren, Osten ; Lorentzon, Mattias ; Luben, Robert N. ; Maixner, William ; McGuigan, Fiona E. ; Medina-Gomez, Carolina ; Meitinger, Thomas ; Melhus, Hakan ; Mellstrom, Dan ; Melov, Simon ; Michaelsson, Karl ; Mitchell, Braxton D. ; Morris, Andrew P. ; Mosekilde, Leif ; Newman, Anne ; Nielson, Carrie M. ; O'Connell, Jeffrey R. ; Oostra, Ben A. ; Orwoll, Eric S. ; Palotie, Aarno ; Parker, Stephen C. J. ; Peacock, Munro ; Perola, Markus ; Peters, Annette ; Polasek, Ozren ; Prince, Richard L. ; Raikkonen, Katri ; Ralston, Stuart H. ; Ripatti, Samuli ; Robbins, John A. ; Rotter, Jerome I. ; Rudan, Igor ; Salomaa, Veikko ; Satterfield, Suzanne ; Schadt, Eric E. ; Schipf, Sabine ; Scott, Laura ; Sehmi, Joban ; Shen, Jian ; Shin, Chan Soo ; Sigurdsson, Gunnar ; Smith, Shad ; Soranzo, Nicole ; Stancakova, Alena ; Steinhagen-Thiessen, Elisabeth ; Streeten, Elizabeth A. ; Styrkarsdottir, Unnur ; Swart, Karin M. A. ; Tan, Sian-Tsung ; Tarnopolsky, Mark A. ; Thompson, Patricia ; Thomson, Cynthia A. ; Thorsteinsdottir, Unnur ; Tikkanen, Emmi ; Tranah, Gregory J. ; Tuomilehto, Jaakko ; van Schoor, Natasja M. ; Verma, Arjun ; Vollenweider, Peter ; Voelzke, Henry ; Wactawski-Wende, Jean ; Walker, Mark ; Weedon, Michael N. ; Welch, Ryan ; Wichmann, H. -Erich ; Widen, Elisabeth ; Williams, Frances M. K. ; Wilson, James F. ; Wright, Nicole C. ; Xie, Weijia ; Yu, Lei ; Zhou, Yanhua ; Chambers, John C. ; Doring, Angela ; van Duijn, Cornelia M. ; Econs, Michael J. ; Gudnason, Vilmundur ; Kooner, Jaspal S. ; Psaty, Bruce M. ; Spector, Timothy D. ; Stefansson, Kari ; Rivadeneira, Fernando ; Uitterlinden, Andre G. ; Wareham, Nicholas J. ; Ossowski, Vicky ; Waterworth, Dawn ; Loos, Ruth J. F. ; Karasik, David ; Harris, Tamara B. ; Ohlsson, Claes ; Kiel, Douglas P. / Large meta-analysis of genome-wide association studies identifies five loci for lean body mass. In: Nature Communications. 2017 ; Vol. 8.
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title = "Large meta-analysis of genome-wide association studies identifies five loci for lean body mass",
keywords = "SKELETAL-MUSCLE MASS, BONE-MINERAL DENSITY, PHYSICAL-DISABILITY, INSULIN-RESISTANCE, GENE-EXPRESSION, UNITED-STATES, HUMAN HEIGHT, VARIANTS, OBESITY, SARCOPENIA, 3121 Internal medicine",
author = "Zillikens, {M. Carola} and Serkalem Demissie and Yi-Hsiang Hsu and Yerges-Armstrong, {Laura M.} and Wen-Chi Chou and Lisette Stolk and Gregory Livshits and Linda Broer and Toby Johnson and Koller, {Daniel L.} and Zoltyn Kutalik and Jian'an Luan and Ida Malkin and Ried, {Janina S.} and Smith, {Albert V.} and Gudmar Thorleifsson and Liesbeth Vandenput and Zhao, {Jing Hua} and Weihua Zhang and Ali Aghdassi and Kristina Akesson and Najaf Amin and Baier, {Leslie J.} and Ines Barroso and Bennett, {David A.} and Lars Bertram and Rainer Biffar and Murielle Bochud and Michael Boehnke and Borecki, {Ingrid B.} and Buchman, {Aron S.} and Liisa Byberg and Harry Campbell and Obanda, {Natalia Campos} and Cauley, {Jane A.} and Cawthon, {Peggy M.} and Henna Cederberg and Zhao Chen and Cho, {Nam H.} and Choi, {Hyung Jin} and Melina Claussnitzer and Francis Collins and Cummings, {Steven R.} and {De Jager}, {Philip L.} and Ilja Demuth and Dhonukshe-Rutten, {Rosalie A. M.} and Luda Diatchenko and Gudny Eiriksdottir and Enneman, {Anke W.} and Mike Erdos and Eriksson, {Johan G.} and Joel Eriksson and Karol Estrada and Evans, {Daniel S.} and Feitosa, {Mary F.} and Mao Fu and Melissa Garcia and Christian Gieger and Thomas Girke and Glazer, {Nicole L.} and Harald Grallert and Jagvir Grewal and Bok-Ghee Han and Hanson, {Robert L.} and Caroline Hayward and Albert Hofman and Hoffman, {Eric P.} and Georg Homuth and Wen-Chi Hsueh and Hubal, {Monica J.} and Alan Hubbard and Huffman, {Kim M.} and Husted, {Lise B.} and Thomas Illig and Erik Ingelsson and Till Ittermann and John-Olov Jansson and Jordan, {Joanne M.} and Antti Jula and Magnus Karlsson and Kay-Tee Khaw and Kilpainen, {Tuomas O.} and Norman Klopp and Kloth, {Jacqueline S. L.} and Koistinen, {Heikki A.} and Kraus, {William E.} and Stephen Kritchevsky and Teemu Kuulasmaa and Johanna Kuusisto and Markku Laakso and Jari Lahti and Thomas Lang and Langdahl, {Bente L.} and Launer, {Lenore J.} and Jong-Young Lee and Lerch, {Markus M.} and Lewis, {Joshua R.} and Lars Lind and Cecilia Lindgren and Yongmei Liu and Tian Liu and Youfang Liu and Osten Ljunggren and Mattias Lorentzon and Luben, {Robert N.} and William Maixner and McGuigan, {Fiona E.} and Carolina Medina-Gomez and Thomas Meitinger and Hakan Melhus and Dan Mellstrom and Simon Melov and Karl Michaelsson and Mitchell, {Braxton D.} and Morris, {Andrew P.} and Leif Mosekilde and Anne Newman and Nielson, {Carrie M.} and O'Connell, {Jeffrey R.} and Oostra, {Ben A.} and Orwoll, {Eric S.} and Aarno Palotie and Parker, {Stephen C. J.} and Munro Peacock and Markus Perola and Annette Peters and Ozren Polasek and Prince, {Richard L.} and Katri Raikkonen and Ralston, {Stuart H.} and Samuli Ripatti and Robbins, {John A.} and Rotter, {Jerome I.} and Igor Rudan and Veikko Salomaa and Suzanne Satterfield and Schadt, {Eric E.} and Sabine Schipf and Laura Scott and Joban Sehmi and Jian Shen and Shin, {Chan Soo} and Gunnar Sigurdsson and Shad Smith and Nicole Soranzo and Alena Stancakova and Elisabeth Steinhagen-Thiessen and Streeten, {Elizabeth A.} and Unnur Styrkarsdottir and Swart, {Karin M. A.} and Sian-Tsung Tan and Tarnopolsky, {Mark A.} and Patricia Thompson and Thomson, {Cynthia A.} and Unnur Thorsteinsdottir and Emmi Tikkanen and Tranah, {Gregory J.} and Jaakko Tuomilehto and {van Schoor}, {Natasja M.} and Arjun Verma and Peter Vollenweider and Henry Voelzke and Jean Wactawski-Wende and Mark Walker and Weedon, {Michael N.} and Ryan Welch and Wichmann, {H. -Erich} and Elisabeth Widen and Williams, {Frances M. K.} and Wilson, {James F.} and Wright, {Nicole C.} and Weijia Xie and Lei Yu and Yanhua Zhou and Chambers, {John C.} and Angela Doring and {van Duijn}, {Cornelia M.} and Econs, {Michael J.} and Vilmundur Gudnason and Kooner, {Jaspal S.} and Psaty, {Bruce M.} and Spector, {Timothy D.} and Kari Stefansson and Fernando Rivadeneira and Uitterlinden, {Andre G.} and Wareham, {Nicholas J.} and Vicky Ossowski and Dawn Waterworth and Loos, {Ruth J. F.} and David Karasik and Harris, {Tamara B.} and Claes Ohlsson and Kiel, {Douglas P.}",
year = "2017",
month = "7",
day = "19",
doi = "10.1038/s41467-017-00031-7",
language = "English",
volume = "8",
journal = "Nature Communications",
issn = "2041-1723",
publisher = "Nature Publishing Group",

}

Zillikens, MC, Demissie, S, Hsu, Y-H, Yerges-Armstrong, LM, Chou, W-C, Stolk, L, Livshits, G, Broer, L, Johnson, T, Koller, DL, Kutalik, Z, Luan, J, Malkin, I, Ried, JS, Smith, AV, Thorleifsson, G, Vandenput, L, Zhao, JH, Zhang, W, Aghdassi, A, Akesson, K, Amin, N, Baier, LJ, Barroso, I, Bennett, DA, Bertram, L, Biffar, R, Bochud, M, Boehnke, M, Borecki, IB, Buchman, AS, Byberg, L, Campbell, H, Obanda, NC, Cauley, JA, Cawthon, PM, Cederberg, H, Chen, Z, Cho, NH, Choi, HJ, Claussnitzer, M, Collins, F, Cummings, SR, De Jager, PL, Demuth, I, Dhonukshe-Rutten, RAM, Diatchenko, L, Eiriksdottir, G, Enneman, AW, Erdos, M, Eriksson, JG, Eriksson, J, Estrada, K, Evans, DS, Feitosa, MF, Fu, M, Garcia, M, Gieger, C, Girke, T, Glazer, NL, Grallert, H, Grewal, J, Han, B-G, Hanson, RL, Hayward, C, Hofman, A, Hoffman, EP, Homuth, G, Hsueh, W-C, Hubal, MJ, Hubbard, A, Huffman, KM, Husted, LB, Illig, T, Ingelsson, E, Ittermann, T, Jansson, J-O, Jordan, JM, Jula, A, Karlsson, M, Khaw, K-T, Kilpainen, TO, Klopp, N, Kloth, JSL, Koistinen, HA, Kraus, WE, Kritchevsky, S, Kuulasmaa, T, Kuusisto, J, Laakso, M, Lahti, J, Lang, T, Langdahl, BL, Launer, LJ, Lee, J-Y, Lerch, MM, Lewis, JR, Lind, L, Lindgren, C, Liu, Y, Liu, T, Liu, Y, Ljunggren, O, Lorentzon, M, Luben, RN, Maixner, W, McGuigan, FE, Medina-Gomez, C, Meitinger, T, Melhus, H, Mellstrom, D, Melov, S, Michaelsson, K, Mitchell, BD, Morris, AP, Mosekilde, L, Newman, A, Nielson, CM, O'Connell, JR, Oostra, BA, Orwoll, ES, Palotie, A, Parker, SCJ, Peacock, M, Perola, M, Peters, A, Polasek, O, Prince, RL, Raikkonen, K, Ralston, SH, Ripatti, S, Robbins, JA, Rotter, JI, Rudan, I, Salomaa, V, Satterfield, S, Schadt, EE, Schipf, S, Scott, L, Sehmi, J, Shen, J, Shin, CS, Sigurdsson, G, Smith, S, Soranzo, N, Stancakova, A, Steinhagen-Thiessen, E, Streeten, EA, Styrkarsdottir, U, Swart, KMA, Tan, S-T, Tarnopolsky, MA, Thompson, P, Thomson, CA, Thorsteinsdottir, U, Tikkanen, E, Tranah, GJ, Tuomilehto, J, van Schoor, NM, Verma, A, Vollenweider, P, Voelzke, H, Wactawski-Wende, J, Walker, M, Weedon, MN, Welch, R, Wichmann, H-E, Widen, E, Williams, FMK, Wilson, JF, Wright, NC, Xie, W, Yu, L, Zhou, Y, Chambers, JC, Doring, A, van Duijn, CM, Econs, MJ, Gudnason, V, Kooner, JS, Psaty, BM, Spector, TD, Stefansson, K, Rivadeneira, F, Uitterlinden, AG, Wareham, NJ, Ossowski, V, Waterworth, D, Loos, RJF, Karasik, D, Harris, TB, Ohlsson, C & Kiel, DP 2017, 'Large meta-analysis of genome-wide association studies identifies five loci for lean body mass', Nature Communications, vol. 8, 80. https://doi.org/10.1038/s41467-017-00031-7

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass. / Zillikens, M. Carola; Demissie, Serkalem; Hsu, Yi-Hsiang; Yerges-Armstrong, Laura M.; Chou, Wen-Chi; Stolk, Lisette; Livshits, Gregory; Broer, Linda; Johnson, Toby; Koller, Daniel L.; Kutalik, Zoltyn; Luan, Jian'an; Malkin, Ida; Ried, Janina S.; Smith, Albert V.; Thorleifsson, Gudmar; Vandenput, Liesbeth; Zhao, Jing Hua; Zhang, Weihua; Aghdassi, Ali; Akesson, Kristina; Amin, Najaf; Baier, Leslie J.; Barroso, Ines; Bennett, David A.; Bertram, Lars; Biffar, Rainer; Bochud, Murielle; Boehnke, Michael; Borecki, Ingrid B.; Buchman, Aron S.; Byberg, Liisa; Campbell, Harry; Obanda, Natalia Campos; Cauley, Jane A.; Cawthon, Peggy M.; Cederberg, Henna; Chen, Zhao; Cho, Nam H.; Choi, Hyung Jin; Claussnitzer, Melina; Collins, Francis; Cummings, Steven R.; De Jager, Philip L.; Demuth, Ilja; Dhonukshe-Rutten, Rosalie A. M.; Diatchenko, Luda; Eiriksdottir, Gudny; Enneman, Anke W.; Erdos, Mike; Eriksson, Johan G.; Eriksson, Joel; Estrada, Karol; Evans, Daniel S.; Feitosa, Mary F.; Fu, Mao; Garcia, Melissa; Gieger, Christian; Girke, Thomas; Glazer, Nicole L.; Grallert, Harald; Grewal, Jagvir; Han, Bok-Ghee; Hanson, Robert L.; Hayward, Caroline; Hofman, Albert; Hoffman, Eric P.; Homuth, Georg; Hsueh, Wen-Chi; Hubal, Monica J.; Hubbard, Alan; Huffman, Kim M.; Husted, Lise B.; Illig, Thomas; Ingelsson, Erik; Ittermann, Till; Jansson, John-Olov; Jordan, Joanne M.; Jula, Antti; Karlsson, Magnus; Khaw, Kay-Tee; Kilpainen, Tuomas O.; Klopp, Norman; Kloth, Jacqueline S. L.; Koistinen, Heikki A.; Kraus, William E.; Kritchevsky, Stephen; Kuulasmaa, Teemu; Kuusisto, Johanna; Laakso, Markku; Lahti, Jari; Lang, Thomas; Langdahl, Bente L.; Launer, Lenore J.; Lee, Jong-Young; Lerch, Markus M.; Lewis, Joshua R.; Lind, Lars; Lindgren, Cecilia; Liu, Yongmei; Liu, Tian; Liu, Youfang; Ljunggren, Osten; Lorentzon, Mattias; Luben, Robert N.; Maixner, William; McGuigan, Fiona E.; Medina-Gomez, Carolina; Meitinger, Thomas; Melhus, Hakan; Mellstrom, Dan; Melov, Simon; Michaelsson, Karl; Mitchell, Braxton D.; Morris, Andrew P.; Mosekilde, Leif; Newman, Anne; Nielson, Carrie M.; O'Connell, Jeffrey R.; Oostra, Ben A.; Orwoll, Eric S.; Palotie, Aarno; Parker, Stephen C. J.; Peacock, Munro; Perola, Markus; Peters, Annette; Polasek, Ozren; Prince, Richard L.; Raikkonen, Katri; Ralston, Stuart H.; Ripatti, Samuli; Robbins, John A.; Rotter, Jerome I.; Rudan, Igor; Salomaa, Veikko; Satterfield, Suzanne; Schadt, Eric E.; Schipf, Sabine; Scott, Laura; Sehmi, Joban; Shen, Jian; Shin, Chan Soo; Sigurdsson, Gunnar; Smith, Shad; Soranzo, Nicole; Stancakova, Alena; Steinhagen-Thiessen, Elisabeth; Streeten, Elizabeth A.; Styrkarsdottir, Unnur; Swart, Karin M. A.; Tan, Sian-Tsung; Tarnopolsky, Mark A.; Thompson, Patricia; Thomson, Cynthia A.; Thorsteinsdottir, Unnur; Tikkanen, Emmi; Tranah, Gregory J.; Tuomilehto, Jaakko; van Schoor, Natasja M.; Verma, Arjun; Vollenweider, Peter; Voelzke, Henry; Wactawski-Wende, Jean; Walker, Mark; Weedon, Michael N.; Welch, Ryan; Wichmann, H. -Erich; Widen, Elisabeth; Williams, Frances M. K.; Wilson, James F.; Wright, Nicole C.; Xie, Weijia; Yu, Lei; Zhou, Yanhua; Chambers, John C.; Doring, Angela; van Duijn, Cornelia M.; Econs, Michael J.; Gudnason, Vilmundur; Kooner, Jaspal S.; Psaty, Bruce M.; Spector, Timothy D.; Stefansson, Kari; Rivadeneira, Fernando; Uitterlinden, Andre G.; Wareham, Nicholas J.; Ossowski, Vicky; Waterworth, Dawn; Loos, Ruth J. F.; Karasik, David; Harris, Tamara B.; Ohlsson, Claes; Kiel, Douglas P.

In: Nature Communications, Vol. 8, 80, 19.07.2017.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

AU - Zillikens, M. Carola

AU - Demissie, Serkalem

AU - Hsu, Yi-Hsiang

AU - Yerges-Armstrong, Laura M.

AU - Chou, Wen-Chi

AU - Stolk, Lisette

AU - Livshits, Gregory

AU - Broer, Linda

AU - Johnson, Toby

AU - Koller, Daniel L.

AU - Kutalik, Zoltyn

AU - Luan, Jian'an

AU - Malkin, Ida

AU - Ried, Janina S.

AU - Smith, Albert V.

AU - Thorleifsson, Gudmar

AU - Vandenput, Liesbeth

AU - Zhao, Jing Hua

AU - Zhang, Weihua

AU - Aghdassi, Ali

AU - Akesson, Kristina

AU - Amin, Najaf

AU - Baier, Leslie J.

AU - Barroso, Ines

AU - Bennett, David A.

AU - Bertram, Lars

AU - Biffar, Rainer

AU - Bochud, Murielle

AU - Boehnke, Michael

AU - Borecki, Ingrid B.

AU - Buchman, Aron S.

AU - Byberg, Liisa

AU - Campbell, Harry

AU - Obanda, Natalia Campos

AU - Cauley, Jane A.

AU - Cawthon, Peggy M.

AU - Cederberg, Henna

AU - Chen, Zhao

AU - Cho, Nam H.

AU - Choi, Hyung Jin

AU - Claussnitzer, Melina

AU - Collins, Francis

AU - Cummings, Steven R.

AU - De Jager, Philip L.

AU - Demuth, Ilja

AU - Dhonukshe-Rutten, Rosalie A. M.

AU - Diatchenko, Luda

AU - Eiriksdottir, Gudny

AU - Enneman, Anke W.

AU - Erdos, Mike

AU - Eriksson, Johan G.

AU - Eriksson, Joel

AU - Estrada, Karol

AU - Evans, Daniel S.

AU - Feitosa, Mary F.

AU - Fu, Mao

AU - Garcia, Melissa

AU - Gieger, Christian

AU - Girke, Thomas

AU - Glazer, Nicole L.

AU - Grallert, Harald

AU - Grewal, Jagvir

AU - Han, Bok-Ghee

AU - Hanson, Robert L.

AU - Hayward, Caroline

AU - Hofman, Albert

AU - Hoffman, Eric P.

AU - Homuth, Georg

AU - Hsueh, Wen-Chi

AU - Hubal, Monica J.

AU - Hubbard, Alan

AU - Huffman, Kim M.

AU - Husted, Lise B.

AU - Illig, Thomas

AU - Ingelsson, Erik

AU - Ittermann, Till

AU - Jansson, John-Olov

AU - Jordan, Joanne M.

AU - Jula, Antti

AU - Karlsson, Magnus

AU - Khaw, Kay-Tee

AU - Kilpainen, Tuomas O.

AU - Klopp, Norman

AU - Kloth, Jacqueline S. L.

AU - Koistinen, Heikki A.

AU - Kraus, William E.

AU - Kritchevsky, Stephen

AU - Kuulasmaa, Teemu

AU - Kuusisto, Johanna

AU - Laakso, Markku

AU - Lahti, Jari

AU - Lang, Thomas

AU - Langdahl, Bente L.

AU - Launer, Lenore J.

AU - Lee, Jong-Young

AU - Lerch, Markus M.

AU - Lewis, Joshua R.

AU - Lind, Lars

AU - Lindgren, Cecilia

AU - Liu, Yongmei

AU - Liu, Tian

AU - Liu, Youfang

AU - Ljunggren, Osten

AU - Lorentzon, Mattias

AU - Luben, Robert N.

AU - Maixner, William

AU - McGuigan, Fiona E.

AU - Medina-Gomez, Carolina

AU - Meitinger, Thomas

AU - Melhus, Hakan

AU - Mellstrom, Dan

AU - Melov, Simon

AU - Michaelsson, Karl

AU - Mitchell, Braxton D.

AU - Morris, Andrew P.

AU - Mosekilde, Leif

AU - Newman, Anne

AU - Nielson, Carrie M.

AU - O'Connell, Jeffrey R.

AU - Oostra, Ben A.

AU - Orwoll, Eric S.

AU - Palotie, Aarno

AU - Parker, Stephen C. J.

AU - Peacock, Munro

AU - Perola, Markus

AU - Peters, Annette

AU - Polasek, Ozren

AU - Prince, Richard L.

AU - Raikkonen, Katri

AU - Ralston, Stuart H.

AU - Ripatti, Samuli

AU - Robbins, John A.

AU - Rotter, Jerome I.

AU - Rudan, Igor

AU - Salomaa, Veikko

AU - Satterfield, Suzanne

AU - Schadt, Eric E.

AU - Schipf, Sabine

AU - Scott, Laura

AU - Sehmi, Joban

AU - Shen, Jian

AU - Shin, Chan Soo

AU - Sigurdsson, Gunnar

AU - Smith, Shad

AU - Soranzo, Nicole

AU - Stancakova, Alena

AU - Steinhagen-Thiessen, Elisabeth

AU - Streeten, Elizabeth A.

AU - Styrkarsdottir, Unnur

AU - Swart, Karin M. A.

AU - Tan, Sian-Tsung

AU - Tarnopolsky, Mark A.

AU - Thompson, Patricia

AU - Thomson, Cynthia A.

AU - Thorsteinsdottir, Unnur

AU - Tikkanen, Emmi

AU - Tranah, Gregory J.

AU - Tuomilehto, Jaakko

AU - van Schoor, Natasja M.

AU - Verma, Arjun

AU - Vollenweider, Peter

AU - Voelzke, Henry

AU - Wactawski-Wende, Jean

AU - Walker, Mark

AU - Weedon, Michael N.

AU - Welch, Ryan

AU - Wichmann, H. -Erich

AU - Widen, Elisabeth

AU - Williams, Frances M. K.

AU - Wilson, James F.

AU - Wright, Nicole C.

AU - Xie, Weijia

AU - Yu, Lei

AU - Zhou, Yanhua

AU - Chambers, John C.

AU - Doring, Angela

AU - van Duijn, Cornelia M.

AU - Econs, Michael J.

AU - Gudnason, Vilmundur

AU - Kooner, Jaspal S.

AU - Psaty, Bruce M.

AU - Spector, Timothy D.

AU - Stefansson, Kari

AU - Rivadeneira, Fernando

AU - Uitterlinden, Andre G.

AU - Wareham, Nicholas J.

AU - Ossowski, Vicky

AU - Waterworth, Dawn

AU - Loos, Ruth J. F.

AU - Karasik, David

AU - Harris, Tamara B.

AU - Ohlsson, Claes

AU - Kiel, Douglas P.

PY - 2017/7/19

Y1 - 2017/7/19

KW - SKELETAL-MUSCLE MASS

KW - BONE-MINERAL DENSITY

KW - PHYSICAL-DISABILITY

KW - INSULIN-RESISTANCE

KW - GENE-EXPRESSION

KW - UNITED-STATES

KW - HUMAN HEIGHT

KW - VARIANTS

KW - OBESITY

KW - SARCOPENIA

KW - 3121 Internal medicine

U2 - 10.1038/s41467-017-00031-7

DO - 10.1038/s41467-017-00031-7

M3 - Article

VL - 8

JO - Nature Communications

JF - Nature Communications

SN - 2041-1723

M1 - 80

ER -