Large-scale genotyping identifies 41 new loci associated with breast cancer risk

Kyriaki Michailidou; Per Hall; Anna Gonzalez-Neira; Maya Ghoussaini; Joe Dennis; Roger L. Milne; Marjanka K. Schmidt; Jenny Chang-Claude; Stig E. Bojesen; Manjeet K. Bolla; Qin Wang; Ed Dicks; Andrew Lee; Clare Turnbull; Nazneen Rahman; Olivia Fletcher; Julian Peto; Lorna Gibson; Isabel dos Santos Silva; Heli Nevanlinna; Taru A. Muranen; Kristiina Aittomäki; Carl Blomqvist; Kamila Czene; Astrid Irwanto; Jianjun Liu; Quinten Waisfisz; Hanne Meijers-Heijboer; Muriel Adank; Rob B. van der Luijt; Rebecca Hein; Norbert Dahmen; Lars Beckman; Alfons Meindl; Rita K. Schmutzler; Bertram Mueller-Myhsok; Peter Lichtner; John L. Hopper; Melissa C. Southey; Enes Makalic; Daniel F. Schmidt; Andre G. Uitterlinden; Albert Hofman; David J. Hunter; Stephen J. Chanock; Daniel Vincent; Francois Bacot; Daniel C. Tessier; Sander Canisius; Tuomas Heikkinen; Breast Ovarian Canc Susceptibility; Hereditary Breast Ovarian Canc Res; kConFab Investigators; Australian Ovarian Can Study Grp; GENICA Gene Environm Interaction B

doi:10.1038/ng.2563

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

Kyriaki Michailidou, Per Hall, Anna Gonzalez-Neira, Maya Ghoussaini, Joe Dennis, Roger L. Milne, Marjanka K. Schmidt, Jenny Chang-Claude, Stig E. Bojesen, Manjeet K. Bolla, Qin Wang, Ed Dicks, Andrew Lee, Clare Turnbull, Nazneen Rahman, Olivia Fletcher, Julian Peto, Lorna Gibson, Isabel dos Santos Silva, Heli NevanlinnaTaru A. Muranen, Kristiina Aittomäki, Carl Blomqvist, Kamila Czene, Astrid Irwanto, Jianjun Liu, Quinten Waisfisz, Hanne Meijers-Heijboer, Muriel Adank, Rob B. van der Luijt, Rebecca Hein, Norbert Dahmen, Lars Beckman, Alfons Meindl, Rita K. Schmutzler, Bertram Mueller-Myhsok, Peter Lichtner, John L. Hopper, Melissa C. Southey, Enes Makalic, Daniel F. Schmidt, Andre G. Uitterlinden, Albert Hofman, David J. Hunter, Stephen J. Chanock, Daniel Vincent, Francois Bacot, Daniel C. Tessier, Sander Canisius, Tuomas Heikkinen, Breast Ovarian Canc Susceptibility, Hereditary Breast Ovarian Canc Res, kConFab Investigators, Australian Ovarian Can Study Grp, GENICA Gene Environm Interaction B

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Nature Genetics
Volume	45
Issue number	4
Pages (from-to)	353-361
Number of pages	9
ISSN	1061-4036
DOIs	https://doi.org/10.1038/ng.2563
Publication status	Published - Apr 2013
MoE publication type	A1 Journal article-refereed

Fields of Science

GENOME-WIDE ASSOCIATION
HORMONE-RELATED PROTEIN
SUSCEPTIBILITY LOCI
COMMON VARIANTS
CONFER SUSCEPTIBILITY
SIGNALING PATHWAY
14Q24.1 RAD51L1
GENE
CONSORTIUM
EXPRESSION
3122 Cancers
3123 Gynaecology and paediatrics
3111 Biomedicine

Access to Document

10.1038/ng.2563

Cite this

Michailidou, K., Hall, P., Gonzalez-Neira, A., Ghoussaini, M., Dennis, J., Milne, R. L., Schmidt, M. K., Chang-Claude, J., Bojesen, S. E., Bolla, M. K., Wang, Q., Dicks, E., Lee, A., Turnbull, C., Rahman, N., Fletcher, O., Peto, J., Gibson, L., Silva, I. D. S., ... GENICA Gene Environm Interaction B (2013). Large-scale genotyping identifies 41 new loci associated with breast cancer risk. Nature Genetics, 45(4), 353-361. https://doi.org/10.1038/ng.2563

@article{e15176d9f2544e8da8ce98aca1f29803,

title = "Large-scale genotyping identifies 41 new loci associated with breast cancer risk",

keywords = "GENOME-WIDE ASSOCIATION, HORMONE-RELATED PROTEIN, SUSCEPTIBILITY LOCI, COMMON VARIANTS, CONFER SUSCEPTIBILITY, SIGNALING PATHWAY, 14Q24.1 RAD51L1, GENE, CONSORTIUM, EXPRESSION, 3122 Cancers, 3123 Gynaecology and paediatrics, 3111 Biomedicine",

author = "Kyriaki Michailidou and Per Hall and Anna Gonzalez-Neira and Maya Ghoussaini and Joe Dennis and Milne, {Roger L.} and Schmidt, {Marjanka K.} and Jenny Chang-Claude and Bojesen, {Stig E.} and Bolla, {Manjeet K.} and Qin Wang and Ed Dicks and Andrew Lee and Clare Turnbull and Nazneen Rahman and Olivia Fletcher and Julian Peto and Lorna Gibson and Silva, {Isabel dos Santos} and Heli Nevanlinna and Muranen, {Taru A.} and Kristiina Aittom{\"a}ki and Carl Blomqvist and Kamila Czene and Astrid Irwanto and Jianjun Liu and Quinten Waisfisz and Hanne Meijers-Heijboer and Muriel Adank and {van der Luijt}, {Rob B.} and Rebecca Hein and Norbert Dahmen and Lars Beckman and Alfons Meindl and Schmutzler, {Rita K.} and Bertram Mueller-Myhsok and Peter Lichtner and Hopper, {John L.} and Southey, {Melissa C.} and Enes Makalic and Schmidt, {Daniel F.} and Uitterlinden, {Andre G.} and Albert Hofman and Hunter, {David J.} and Chanock, {Stephen J.} and Daniel Vincent and Francois Bacot and Tessier, {Daniel C.} and Sander Canisius and Tuomas Heikkinen and {Breast Ovarian Canc Susceptibility} and {Hereditary Breast Ovarian Canc Res} and {kConFab Investigators} and {Australian Ovarian Can Study Grp} and {GENICA Gene Environm Interaction B}",

year = "2013",

month = apr,

doi = "10.1038/ng.2563",

language = "English",

volume = "45",

pages = "353--361",

journal = "Nature Genetics",

issn = "1061-4036",

publisher = "Nature Publishing Group",

number = "4",

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Michailidou, K, Hall, P, Gonzalez-Neira, A, Ghoussaini, M, Dennis, J, Milne, RL, Schmidt, MK, Chang-Claude, J, Bojesen, SE, Bolla, MK, Wang, Q, Dicks, E, Lee, A, Turnbull, C, Rahman, N, Fletcher, O, Peto, J, Gibson, L, Silva, IDS, Nevanlinna, H , Muranen, TA , Aittomäki, K , Blomqvist, C, Czene, K, Irwanto, A, Liu, J, Waisfisz, Q, Meijers-Heijboer, H, Adank, M, van der Luijt, RB, Hein, R, Dahmen, N, Beckman, L, Meindl, A, Schmutzler, RK, Mueller-Myhsok, B, Lichtner, P, Hopper, JL, Southey, MC, Makalic, E, Schmidt, DF, Uitterlinden, AG, Hofman, A, Hunter, DJ, Chanock, SJ, Vincent, D, Bacot, F, Tessier, DC, Canisius, S, Heikkinen, T, Breast Ovarian Canc Susceptibility, Hereditary Breast Ovarian Canc Res, kConFab Investigators, Australian Ovarian Can Study Grp & GENICA Gene Environm Interaction B 2013, 'Large-scale genotyping identifies 41 new loci associated with breast cancer risk', Nature Genetics, vol. 45, no. 4, pp. 353-361. https://doi.org/10.1038/ng.2563

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T1 - Large-scale genotyping identifies 41 new loci associated with breast cancer risk

AU - Michailidou, Kyriaki

AU - Hall, Per

AU - Gonzalez-Neira, Anna

AU - Ghoussaini, Maya

AU - Dennis, Joe

AU - Milne, Roger L.

AU - Schmidt, Marjanka K.

AU - Chang-Claude, Jenny

AU - Bojesen, Stig E.

AU - Bolla, Manjeet K.

AU - Wang, Qin

AU - Dicks, Ed

AU - Lee, Andrew

AU - Turnbull, Clare

AU - Rahman, Nazneen

AU - Fletcher, Olivia

AU - Peto, Julian

AU - Gibson, Lorna

AU - Silva, Isabel dos Santos

AU - Nevanlinna, Heli

AU - Muranen, Taru A.

AU - Aittomäki, Kristiina

AU - Blomqvist, Carl

AU - Czene, Kamila

AU - Irwanto, Astrid

AU - Liu, Jianjun

AU - Waisfisz, Quinten

AU - Meijers-Heijboer, Hanne

AU - Adank, Muriel

AU - van der Luijt, Rob B.

AU - Hein, Rebecca

AU - Dahmen, Norbert

AU - Beckman, Lars

AU - Meindl, Alfons

AU - Schmutzler, Rita K.

AU - Mueller-Myhsok, Bertram

AU - Lichtner, Peter

AU - Hopper, John L.

AU - Southey, Melissa C.

AU - Makalic, Enes

AU - Schmidt, Daniel F.

AU - Uitterlinden, Andre G.

AU - Hofman, Albert

AU - Hunter, David J.

AU - Chanock, Stephen J.

AU - Vincent, Daniel

AU - Bacot, Francois

AU - Tessier, Daniel C.

AU - Canisius, Sander

AU - Heikkinen, Tuomas

AU - Breast Ovarian Canc Susceptibility

AU - Hereditary Breast Ovarian Canc Res

AU - kConFab Investigators

AU - Australian Ovarian Can Study Grp

AU - GENICA Gene Environm Interaction B

PY - 2013/4

Y1 - 2013/4

KW - GENOME-WIDE ASSOCIATION

KW - HORMONE-RELATED PROTEIN

KW - SUSCEPTIBILITY LOCI

KW - COMMON VARIANTS

KW - CONFER SUSCEPTIBILITY

KW - SIGNALING PATHWAY

KW - 14Q24.1 RAD51L1

KW - GENE

KW - CONSORTIUM

KW - EXPRESSION

KW - 3122 Cancers

KW - 3123 Gynaecology and paediatrics

KW - 3111 Biomedicine

U2 - 10.1038/ng.2563

DO - 10.1038/ng.2563

M3 - Article

SN - 1061-4036

VL - 45

SP - 353

EP - 361

JO - Nature Genetics

JF - Nature Genetics

IS - 4

ER -