Lipoteichoic acid modulates inflammatory response in macrophages after phagocytosis of titanium particles through Toll-like receptor 2 cascade and inflammasomes

Yasushi Naganuma; Yuya Takakubo; Tomoyuki Hirayama; Yasunobu Tamaki; Jukka Pajarinen; Kan Sasaki; Stuart B. Goodman; Michiaki Takagi

doi:10.1002/jbm.a.35581

Lipoteichoic acid modulates inflammatory response in macrophages after phagocytosis of titanium particles through Toll-like receptor 2 cascade and inflammasomes

Yasushi Naganuma, Yuya Takakubo, Tomoyuki Hirayama, Yasunobu Tamaki, Jukka Pajarinen, Kan Sasaki, Stuart B. Goodman, Michiaki Takagi

Medicum

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Journal of Biomedical Materials Research. Part A
Volume	104
Issue number	2
Pages (from-to)	435-444
Number of pages	10
ISSN	1549-3296
DOIs	https://doi.org/10.1002/jbm.a.35581
Publication status	Published - Feb 2016
MoE publication type	A1 Journal article-refereed

Fields of Science

total hip arthroplasty
osteolysis
cellular innate immune response
Toll-like receptors
NLRP3 inflammasomes
ORTHOPEDIC WEAR PARTICLES
TOTAL HIP-ARTHROPLASTY
INTERLEUKIN-1-BETA PRODUCTION
STAPHYLOCOCCUS-EPIDERMIDIS
MOLECULAR-IDENTIFICATION
REPLACEMENT IMPLANTS
ADHERENT ENDOTOXIN
OSTEOLYSIS
POLYETHYLENE
EXPRESSION
3111 Biomedicine

Access to Document

10.1002/jbm.a.35581

Cite this

Naganuma, Y., Takakubo, Y., Hirayama, T., Tamaki, Y., Pajarinen, J., Sasaki, K., Goodman, S. B., & Takagi, M. (2016). Lipoteichoic acid modulates inflammatory response in macrophages after phagocytosis of titanium particles through Toll-like receptor 2 cascade and inflammasomes. Journal of Biomedical Materials Research. Part A, 104(2), 435-444. https://doi.org/10.1002/jbm.a.35581

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title = "Lipoteichoic acid modulates inflammatory response in macrophages after phagocytosis of titanium particles through Toll-like receptor 2 cascade and inflammasomes",

keywords = "total hip arthroplasty, osteolysis, cellular innate immune response, Toll-like receptors, NLRP3 inflammasomes, ORTHOPEDIC WEAR PARTICLES, TOTAL HIP-ARTHROPLASTY, INTERLEUKIN-1-BETA PRODUCTION, STAPHYLOCOCCUS-EPIDERMIDIS, MOLECULAR-IDENTIFICATION, REPLACEMENT IMPLANTS, ADHERENT ENDOTOXIN, OSTEOLYSIS, POLYETHYLENE, EXPRESSION, 3111 Biomedicine",

author = "Yasushi Naganuma and Yuya Takakubo and Tomoyuki Hirayama and Yasunobu Tamaki and Jukka Pajarinen and Kan Sasaki and Goodman, {Stuart B.} and Michiaki Takagi",

year = "2016",

month = feb,

doi = "10.1002/jbm.a.35581",

language = "English",

volume = "104",

pages = "435--444",

journal = "Journal of Biomedical Materials Research. Part A",

issn = "1549-3296",

publisher = "Wiley",

number = "2",

}

Naganuma, Y, Takakubo, Y, Hirayama, T, Tamaki, Y, Pajarinen, J, Sasaki, K, Goodman, SB & Takagi, M 2016, 'Lipoteichoic acid modulates inflammatory response in macrophages after phagocytosis of titanium particles through Toll-like receptor 2 cascade and inflammasomes', Journal of Biomedical Materials Research. Part A, vol. 104, no. 2, pp. 435-444. https://doi.org/10.1002/jbm.a.35581

Lipoteichoic acid modulates inflammatory response in macrophages after phagocytosis of titanium particles through Toll-like receptor 2 cascade and inflammasomes. / Naganuma, Yasushi; Takakubo, Yuya; Hirayama, Tomoyuki et al.

In: Journal of Biomedical Materials Research. Part A, Vol. 104, No. 2, 02.2016, p. 435-444.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Lipoteichoic acid modulates inflammatory response in macrophages after phagocytosis of titanium particles through Toll-like receptor 2 cascade and inflammasomes

AU - Naganuma, Yasushi

AU - Takakubo, Yuya

AU - Hirayama, Tomoyuki

AU - Tamaki, Yasunobu

AU - Pajarinen, Jukka

AU - Sasaki, Kan

AU - Goodman, Stuart B.

AU - Takagi, Michiaki

PY - 2016/2

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KW - total hip arthroplasty

KW - osteolysis

KW - cellular innate immune response

KW - Toll-like receptors

KW - NLRP3 inflammasomes

KW - ORTHOPEDIC WEAR PARTICLES

KW - TOTAL HIP-ARTHROPLASTY

KW - INTERLEUKIN-1-BETA PRODUCTION

KW - STAPHYLOCOCCUS-EPIDERMIDIS

KW - MOLECULAR-IDENTIFICATION

KW - REPLACEMENT IMPLANTS

KW - ADHERENT ENDOTOXIN

KW - OSTEOLYSIS

KW - POLYETHYLENE

KW - EXPRESSION

KW - 3111 Biomedicine

U2 - 10.1002/jbm.a.35581

DO - 10.1002/jbm.a.35581

M3 - Article

VL - 104

SP - 435

EP - 444

JO - Journal of Biomedical Materials Research. Part A

JF - Journal of Biomedical Materials Research. Part A

SN - 1549-3296

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ER -