Long-Term Changes in Cyclosporine Pharmacokinetics After Renal Transplantation in Children: Evidence for Saturable Presystemic Metabolism and Effect of NR1I2 Polymorphism

Samuel Fanta, Siv Jonsson, Mats O. Karlsson, Mikko Olavi Niemi, Christer Holmberg, Kalle Hoppu, Janne Backman

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalJournal of Clinical Pharmacology
Volume50
Issue number5
Pages (from-to)581-597
Number of pages17
ISSN0091-2700
DOIs
Publication statusPublished - 2010
MoE publication typeA1 Journal article-refereed

Fields of Science

  • cyclosporine
  • pediatric renal transplantation
  • population pharmacokinetics
  • pharmacogenetics
  • therapeutic drug monitoring
  • POPULATION PHARMACOKINETICS
  • CALCINEURIN INHIBITOR
  • P-GLYCOPROTEIN
  • RECIPIENTS
  • IMPACT
  • IMMUNOSUPPRESSION
  • PHARMACOGENETICS
  • NEPHROTOXICITY
  • IDENTIFICATION
  • MICROEMULSION
  • 312 Clinical medicine

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