Longitudinal single-cell RNA-seq analysis reveals stress-promoted chemoresistance in metastatic ovarian cancer

Kaiyang Zhang; Erdogan Pekcan Erkan; Sanaz Jamalzadeh; Jun Dai; Noora Andersson; Katja Kaipio; Tarja Lamminen; Naziha Mansuri; Kaisa Huhtinen; Olli Carpen; Sakari Hietanen; Jaana Oikkonen; Johanna Hynninen; Anni Virtanen; Antti Häkkinen; Sampsa Hautaniemi; Anna Väharautio

doi:10.1126/sciadv.abm1831

Longitudinal single-cell RNA-seq analysis reveals stress-promoted chemoresistance in metastatic ovarian cancer

Kaiyang Zhang, Erdogan Pekcan Erkan, Sanaz Jamalzadeh, Jun Dai, Noora Andersson, Katja Kaipio, Tarja Lamminen, Naziha Mansuri, Kaisa Huhtinen, Olli Carpen, Sakari Hietanen, Jaana Oikkonen, Johanna Hynninen, Anni Virtanen, Antti Häkkinen, Sampsa Hautaniemi, Anna Väharautio

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	1831
Journal	Science Advances
Volume	8
Issue number	8
Number of pages	18
ISSN	2375-2548
DOIs	https://doi.org/10.1126/sciadv.abm1831
Publication status	Published - Feb 2022
MoE publication type	A1 Journal article-refereed

Fields of Science

HETEROGENEITY
EXPRESSION
MUTATIONS
EVOLUTION
3122 Cancers

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Zhang, K., Erkan, E. P., Jamalzadeh, S., Dai, J., Andersson, N., Kaipio, K., Lamminen, T., Mansuri, N., Huhtinen, K., Carpen, O., Hietanen, S., Oikkonen, J., Hynninen, J., Virtanen, A., Häkkinen, A., Hautaniemi, S., & Väharautio, A. (2022). Longitudinal single-cell RNA-seq analysis reveals stress-promoted chemoresistance in metastatic ovarian cancer. Science Advances, 8(8), Article 1831. https://doi.org/10.1126/sciadv.abm1831

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title = "Longitudinal single-cell RNA-seq analysis reveals stress-promoted chemoresistance in metastatic ovarian cancer",

keywords = "HETEROGENEITY, EXPRESSION, MUTATIONS, EVOLUTION, 3122 Cancers",

author = "Kaiyang Zhang and Erkan, {Erdogan Pekcan} and Sanaz Jamalzadeh and Jun Dai and Noora Andersson and Katja Kaipio and Tarja Lamminen and Naziha Mansuri and Kaisa Huhtinen and Olli Carpen and Sakari Hietanen and Jaana Oikkonen and Johanna Hynninen and Anni Virtanen and Antti H{\"a}kkinen and Sampsa Hautaniemi and Anna V{\"a}harautio",

year = "2022",

month = feb,

doi = "10.1126/sciadv.abm1831",

language = "English",

volume = "8",

journal = "Science Advances",

issn = "2375-2548",

publisher = "American Association for the Advancement of Science (AAAS)",

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Zhang, K, Erkan, EP, Jamalzadeh, S , Dai, J , Andersson, N, Kaipio, K, Lamminen, T, Mansuri, N, Huhtinen, K, Carpen, O, Hietanen, S, Oikkonen, J, Hynninen, J, Virtanen, A , Häkkinen, A , Hautaniemi, S & Väharautio, A 2022, 'Longitudinal single-cell RNA-seq analysis reveals stress-promoted chemoresistance in metastatic ovarian cancer', Science Advances, vol. 8, no. 8, 1831. https://doi.org/10.1126/sciadv.abm1831

TY - JOUR

T1 - Longitudinal single-cell RNA-seq analysis reveals stress-promoted chemoresistance in metastatic ovarian cancer

AU - Zhang, Kaiyang

AU - Erkan, Erdogan Pekcan

AU - Jamalzadeh, Sanaz

AU - Dai, Jun

AU - Andersson, Noora

AU - Kaipio, Katja

AU - Lamminen, Tarja

AU - Mansuri, Naziha

AU - Huhtinen, Kaisa

AU - Carpen, Olli

AU - Hietanen, Sakari

AU - Oikkonen, Jaana

AU - Hynninen, Johanna

AU - Virtanen, Anni

AU - Häkkinen, Antti

AU - Hautaniemi, Sampsa

AU - Väharautio, Anna

PY - 2022/2

Y1 - 2022/2

KW - HETEROGENEITY

KW - EXPRESSION

KW - MUTATIONS

KW - EVOLUTION

KW - 3122 Cancers

U2 - 10.1126/sciadv.abm1831

DO - 10.1126/sciadv.abm1831

M3 - Article

SN - 2375-2548

VL - 8

JO - Science Advances

JF - Science Advances

IS - 8

M1 - 1831

ER -