Loss of CRMP2 O-GlcNAcylation leads to reduced novel object recognition performance in mice

Villo Muha, Ritchie Williamson, Rachel Hills, A.D. McNeilly, T.G. McWilliams, Jana Alonso, Marianne Schimpl, Aneika C. Leney, Albert J.R. Heck, Calum Sutherland, Kevin D. Read, Rory J. McCrimmon, S.P. Brooks, Daan M.F. Van Aalten

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalOpen biology
Volume9
Issue number11
Number of pages15
ISSN2046-2441
DOIs
Publication statusPublished - 2019
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Cognitive function
  • CRMP2
  • Crosstalk
  • O-GlcNAcylation
  • collapsin response mediator protein-2
  • n acetylglucosamine
  • nerve protein
  • signal peptide
  • aging
  • amino acid sequence
  • animal
  • C57BL mouse
  • cell line
  • chemistry
  • cognition
  • exploratory behavior
  • female
  • gene knock-in
  • genetics
  • human
  • male
  • memory disorder
  • metabolism
  • mouse
  • point mutation
  • protein processing
  • short term memory
  • Acetylglucosamine
  • Aging
  • Amino Acid Sequence
  • Animals
  • Cell Line
  • Cognition
  • Exploratory Behavior
  • Female
  • Gene Knock-In Techniques
  • Humans
  • Intercellular Signaling Peptides and Proteins
  • Male
  • Memory Disorders
  • Memory, Short-Term
  • Mice
  • Mice, Inbred C57BL
  • Nerve Tissue Proteins
  • Point Mutation
  • Protein Processing, Post-Translational
  • 1182 Biochemistry, cell and molecular biology

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