Loss of muscleblind splicing factor shortens Caenorhabditis elegans lifespan by reducing the activity of p38 MAPK/PMK-1 and transcription factors ATF-7 and Nrf/SKN-1

Olli Matilainen, Ana R. S. Ribeiro, Jens Verbeeren, Murat Cetinbas, Heini Sood, Ruslan Sadreyev, Susana M. D. A. Garcia

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
Article number114
JournalGenetics
Volume219
Issue number2
Number of pages13
ISSN0016-6731
DOIs
Publication statusPublished - Oct 2021
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Muscleblind splicing factor
  • C. elegans
  • lifespan
  • p38 MAPK
  • PMK-1
  • ATF-1
  • SKN-1
  • mitochondrial stress
  • INNATE IMMUNE-RESPONSES
  • MITOCHONDRIAL DYSFUNCTION
  • FACTOR SKN-1
  • KINASE
  • RNA
  • MAPK
  • PROTEINS
  • PATHWAY
  • STRESS
  • EXPRESSION
  • 1184 Genetics, developmental biology, physiology

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