Lower versus Higher Hemoglobin Threshold for Transfusion in Septic Shock

Lars B. Holst; Nicolai Haase; Jorn Wetterslev; Jan Wernerman; Anne B. Guttormsen; Sari Karlsson; Par I. Johansson; Anders Aneman; Marianne L. Vang; Robert Winding; Lars Nebrich; Helle L. Nibro; Bodil S. Rasmussen; Johnny R. M. Lauridsen; Jane S. Nielsen; Anders Oldner; Ville Pettila; Maria B. Cronhjort; Lasse H. Andersen; Ulf G. Pedersen; Nanna Reiter; Jorgen Wiis; Jonathan O. White; Lene Russell; Klaus J. Thornberg; Peter B. Hjortrup; Rasmus G. Muller; Morten H. Moller; Morten Steensen; Inga Tjader; Kristina Kilsand; Suzanne Odeberg-Wernerman; Brit Sjobo; Helle Bundgaard; Maria A. Thyo; David Lodahl; Rikke Maerkedahl; Carsten Albeck; Dorte Illum; Mary Kruse; Per Winkel; Anders Perner; TRISS Trial Grp; Scandinavian Critical Care Trials

doi:10.1056/NEJMoa1406617

Lower versus Higher Hemoglobin Threshold for Transfusion in Septic Shock

Lars B. Holst, Nicolai Haase, Jorn Wetterslev, Jan Wernerman, Anne B. Guttormsen, Sari Karlsson, Par I. Johansson, Anders Aneman, Marianne L. Vang, Robert Winding, Lars Nebrich, Helle L. Nibro, Bodil S. Rasmussen, Johnny R. M. Lauridsen, Jane S. Nielsen, Anders Oldner, Ville Pettila, Maria B. Cronhjort, Lasse H. Andersen, Ulf G. PedersenNanna Reiter, Jorgen Wiis, Jonathan O. White, Lene Russell, Klaus J. Thornberg, Peter B. Hjortrup, Rasmus G. Muller, Morten H. Moller, Morten Steensen, Inga Tjader, Kristina Kilsand, Suzanne Odeberg-Wernerman, Brit Sjobo, Helle Bundgaard, Maria A. Thyo, David Lodahl, Rikke Maerkedahl, Carsten Albeck, Dorte Illum, Mary Kruse, Per Winkel, Anders Perner, TRISS Trial Grp, Scandinavian Critical Care Trials

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	New England Journal of Medicine
Volume	371
Issue number	15
Pages (from-to)	1381-1391
Number of pages	11
ISSN	0028-4793
DOIs	https://doi.org/10.1056/NEJMoa1406617
Publication status	Published - 9 Oct 2014
MoE publication type	A1 Journal article-refereed

Fields of Science

BLOOD-CELL TRANSFUSION
SEVERE SEPSIS
CRITICAL-CARE
CLINICAL CHARACTERISTICS
UNSELECTED PATIENTS
MULTICENTER COHORT
CRITICALLY-ILL
ORGAN FAILURE
MORTALITY
TRIAL
3121 General medicine, internal medicine and other clinical medicine
3126 Surgery, anesthesiology, intensive care, radiology

Access to Document

10.1056/NEJMoa1406617

Cite this

Holst, L. B., Haase, N., Wetterslev, J., Wernerman, J., Guttormsen, A. B., Karlsson, S., Johansson, P. I., Aneman, A., Vang, M. L., Winding, R., Nebrich, L., Nibro, H. L., Rasmussen, B. S., Lauridsen, J. R. M., Nielsen, J. S., Oldner, A., Pettila, V., Cronhjort, M. B., Andersen, L. H., ... Scandinavian Critical Care Trials (2014). Lower versus Higher Hemoglobin Threshold for Transfusion in Septic Shock. New England Journal of Medicine, 371(15), 1381-1391. https://doi.org/10.1056/NEJMoa1406617

Holst, Lars B. ; Haase, Nicolai ; Wetterslev, Jorn ; Wernerman, Jan ; Guttormsen, Anne B. ; Karlsson, Sari ; Johansson, Par I. ; Aneman, Anders ; Vang, Marianne L. ; Winding, Robert ; Nebrich, Lars ; Nibro, Helle L. ; Rasmussen, Bodil S. ; Lauridsen, Johnny R. M. ; Nielsen, Jane S. ; Oldner, Anders ; Pettila, Ville ; Cronhjort, Maria B. ; Andersen, Lasse H. ; Pedersen, Ulf G. ; Reiter, Nanna ; Wiis, Jorgen ; White, Jonathan O. ; Russell, Lene ; Thornberg, Klaus J. ; Hjortrup, Peter B. ; Muller, Rasmus G. ; Moller, Morten H. ; Steensen, Morten ; Tjader, Inga ; Kilsand, Kristina ; Odeberg-Wernerman, Suzanne ; Sjobo, Brit ; Bundgaard, Helle ; Thyo, Maria A. ; Lodahl, David ; Maerkedahl, Rikke ; Albeck, Carsten ; Illum, Dorte ; Kruse, Mary ; Winkel, Per ; Perner, Anders ; TRISS Trial Grp ; Scandinavian Critical Care Trials. / Lower versus Higher Hemoglobin Threshold for Transfusion in Septic Shock. In: New England Journal of Medicine. 2014 ; Vol. 371, No. 15. pp. 1381-1391.

@article{9cfe3ad2ec334a88b3c248eeae84bcc8,

title = "Lower versus Higher Hemoglobin Threshold for Transfusion in Septic Shock",

keywords = "BLOOD-CELL TRANSFUSION, SEVERE SEPSIS, CRITICAL-CARE, CLINICAL CHARACTERISTICS, UNSELECTED PATIENTS, MULTICENTER COHORT, CRITICALLY-ILL, ORGAN FAILURE, MORTALITY, TRIAL, 3121 General medicine, internal medicine and other clinical medicine, 3126 Surgery, anesthesiology, intensive care, radiology",

author = "Holst, {Lars B.} and Nicolai Haase and Jorn Wetterslev and Jan Wernerman and Guttormsen, {Anne B.} and Sari Karlsson and Johansson, {Par I.} and Anders Aneman and Vang, {Marianne L.} and Robert Winding and Lars Nebrich and Nibro, {Helle L.} and Rasmussen, {Bodil S.} and Lauridsen, {Johnny R. M.} and Nielsen, {Jane S.} and Anders Oldner and Ville Pettila and Cronhjort, {Maria B.} and Andersen, {Lasse H.} and Pedersen, {Ulf G.} and Nanna Reiter and Jorgen Wiis and White, {Jonathan O.} and Lene Russell and Thornberg, {Klaus J.} and Hjortrup, {Peter B.} and Muller, {Rasmus G.} and Moller, {Morten H.} and Morten Steensen and Inga Tjader and Kristina Kilsand and Suzanne Odeberg-Wernerman and Brit Sjobo and Helle Bundgaard and Thyo, {Maria A.} and David Lodahl and Rikke Maerkedahl and Carsten Albeck and Dorte Illum and Mary Kruse and Per Winkel and Anders Perner and {TRISS Trial Grp} and {Scandinavian Critical Care Trials}",

year = "2014",

month = oct,

day = "9",

doi = "10.1056/NEJMoa1406617",

language = "English",

volume = "371",

pages = "1381--1391",

journal = "New England Journal of Medicine",

issn = "0028-4793",

publisher = "Massachusetts Medical Society",

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Holst, LB, Haase, N, Wetterslev, J, Wernerman, J, Guttormsen, AB, Karlsson, S, Johansson, PI, Aneman, A, Vang, ML, Winding, R, Nebrich, L, Nibro, HL, Rasmussen, BS, Lauridsen, JRM, Nielsen, JS, Oldner, A, Pettila, V, Cronhjort, MB, Andersen, LH, Pedersen, UG, Reiter, N, Wiis, J, White, JO, Russell, L, Thornberg, KJ, Hjortrup, PB, Muller, RG, Moller, MH, Steensen, M, Tjader, I, Kilsand, K, Odeberg-Wernerman, S, Sjobo, B, Bundgaard, H, Thyo, MA, Lodahl, D, Maerkedahl, R, Albeck, C, Illum, D, Kruse, M, Winkel, P, Perner, A, TRISS Trial Grp & Scandinavian Critical Care Trials 2014, 'Lower versus Higher Hemoglobin Threshold for Transfusion in Septic Shock', New England Journal of Medicine, vol. 371, no. 15, pp. 1381-1391. https://doi.org/10.1056/NEJMoa1406617

Lower versus Higher Hemoglobin Threshold for Transfusion in Septic Shock. / Holst, Lars B.; Haase, Nicolai; Wetterslev, Jorn; Wernerman, Jan; Guttormsen, Anne B.; Karlsson, Sari; Johansson, Par I.; Aneman, Anders; Vang, Marianne L.; Winding, Robert; Nebrich, Lars; Nibro, Helle L.; Rasmussen, Bodil S.; Lauridsen, Johnny R. M.; Nielsen, Jane S.; Oldner, Anders; Pettila, Ville; Cronhjort, Maria B.; Andersen, Lasse H.; Pedersen, Ulf G.; Reiter, Nanna; Wiis, Jorgen; White, Jonathan O.; Russell, Lene; Thornberg, Klaus J.; Hjortrup, Peter B.; Muller, Rasmus G.; Moller, Morten H.; Steensen, Morten; Tjader, Inga; Kilsand, Kristina; Odeberg-Wernerman, Suzanne; Sjobo, Brit; Bundgaard, Helle; Thyo, Maria A.; Lodahl, David; Maerkedahl, Rikke; Albeck, Carsten; Illum, Dorte; Kruse, Mary; Winkel, Per; Perner, Anders; TRISS Trial Grp; Scandinavian Critical Care Trials.

In: New England Journal of Medicine, Vol. 371, No. 15, 09.10.2014, p. 1381-1391.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Lower versus Higher Hemoglobin Threshold for Transfusion in Septic Shock

AU - Holst, Lars B.

AU - Haase, Nicolai

AU - Wetterslev, Jorn

AU - Wernerman, Jan

AU - Guttormsen, Anne B.

AU - Karlsson, Sari

AU - Johansson, Par I.

AU - Aneman, Anders

AU - Vang, Marianne L.

AU - Winding, Robert

AU - Nebrich, Lars

AU - Nibro, Helle L.

AU - Rasmussen, Bodil S.

AU - Lauridsen, Johnny R. M.

AU - Nielsen, Jane S.

AU - Oldner, Anders

AU - Pettila, Ville

AU - Cronhjort, Maria B.

AU - Andersen, Lasse H.

AU - Pedersen, Ulf G.

AU - Reiter, Nanna

AU - Wiis, Jorgen

AU - White, Jonathan O.

AU - Russell, Lene

AU - Thornberg, Klaus J.

AU - Hjortrup, Peter B.

AU - Muller, Rasmus G.

AU - Moller, Morten H.

AU - Steensen, Morten

AU - Tjader, Inga

AU - Kilsand, Kristina

AU - Odeberg-Wernerman, Suzanne

AU - Sjobo, Brit

AU - Bundgaard, Helle

AU - Thyo, Maria A.

AU - Lodahl, David

AU - Maerkedahl, Rikke

AU - Albeck, Carsten

AU - Illum, Dorte

AU - Kruse, Mary

AU - Winkel, Per

AU - Perner, Anders

AU - TRISS Trial Grp

AU - Scandinavian Critical Care Trials

PY - 2014/10/9

Y1 - 2014/10/9

KW - BLOOD-CELL TRANSFUSION

KW - SEVERE SEPSIS

KW - CRITICAL-CARE

KW - CLINICAL CHARACTERISTICS

KW - UNSELECTED PATIENTS

KW - MULTICENTER COHORT

KW - CRITICALLY-ILL

KW - ORGAN FAILURE

KW - MORTALITY

KW - TRIAL

KW - 3121 General medicine, internal medicine and other clinical medicine

KW - 3126 Surgery, anesthesiology, intensive care, radiology

U2 - 10.1056/NEJMoa1406617

DO - 10.1056/NEJMoa1406617

M3 - Article

VL - 371

SP - 1381

EP - 1391

JO - New England Journal of Medicine

JF - New England Journal of Medicine

SN - 0028-4793

IS - 15

ER -