Lymphatic endothelium stimulates melanoma metastasis and invasion via MMP14-dependent Notch3 and beta 1-integrin activation

Pirita Pekkonen, Sanni Alve, Giuseppe Balistreri, Silvia Gramolelli, Olga Tatti-Bugaeva, Ilkka Paatero, Otso Niiranen, Krista Tuohinto, Nina Perala, Adewale Taiwo, Nadezhda Zinovkina, Pauliina Repo, Katherine Icay, Joanna Ivaska, Pipsa Saharinen, Sampsa Hautaniemi, Kaisa Lehti, Paivi M. Ojala

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
Article number32490
JournaleLife
Volume7
Number of pages28
ISSN2050-084X
DOIs
Publication statusPublished - 1 May 2018
MoE publication typeA1 Journal article-refereed

Fields of Science

  • TO-MESENCHYMAL TRANSITION
  • TUMOR PROGRESSION
  • NODE METASTASIS
  • CELL-ADHESION
  • CANCER
  • METALLOPROTEINASES
  • EXPRESSION
  • PLATFORM
  • VESSELS
  • CCR7
  • 3111 Biomedicine

Cite this

@article{cba1f27711694721b243c8325363fca1,
title = "Lymphatic endothelium stimulates melanoma metastasis and invasion via MMP14-dependent Notch3 and beta 1-integrin activation",
keywords = "TO-MESENCHYMAL TRANSITION, TUMOR PROGRESSION, NODE METASTASIS, CELL-ADHESION, CANCER, METALLOPROTEINASES, EXPRESSION, PLATFORM, VESSELS, CCR7, 3111 Biomedicine",
author = "Pirita Pekkonen and Sanni Alve and Giuseppe Balistreri and Silvia Gramolelli and Olga Tatti-Bugaeva and Ilkka Paatero and Otso Niiranen and Krista Tuohinto and Nina Perala and Adewale Taiwo and Nadezhda Zinovkina and Pauliina Repo and Katherine Icay and Joanna Ivaska and Pipsa Saharinen and Sampsa Hautaniemi and Kaisa Lehti and Ojala, {Paivi M.}",
year = "2018",
month = "5",
day = "1",
doi = "10.7554/eLife.32490",
language = "English",
volume = "7",
journal = "eLife",
issn = "2050-084X",
publisher = "ELIFE SCIENCES PUBLICATIONS LTD",

}

Lymphatic endothelium stimulates melanoma metastasis and invasion via MMP14-dependent Notch3 and beta 1-integrin activation. / Pekkonen, Pirita; Alve, Sanni; Balistreri, Giuseppe; Gramolelli, Silvia; Tatti-Bugaeva, Olga; Paatero, Ilkka; Niiranen, Otso; Tuohinto, Krista; Perala, Nina; Taiwo, Adewale; Zinovkina, Nadezhda; Repo, Pauliina; Icay, Katherine; Ivaska, Joanna; Saharinen, Pipsa; Hautaniemi, Sampsa; Lehti, Kaisa; Ojala, Paivi M.

In: eLife, Vol. 7, 32490, 01.05.2018.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Lymphatic endothelium stimulates melanoma metastasis and invasion via MMP14-dependent Notch3 and beta 1-integrin activation

AU - Pekkonen, Pirita

AU - Alve, Sanni

AU - Balistreri, Giuseppe

AU - Gramolelli, Silvia

AU - Tatti-Bugaeva, Olga

AU - Paatero, Ilkka

AU - Niiranen, Otso

AU - Tuohinto, Krista

AU - Perala, Nina

AU - Taiwo, Adewale

AU - Zinovkina, Nadezhda

AU - Repo, Pauliina

AU - Icay, Katherine

AU - Ivaska, Joanna

AU - Saharinen, Pipsa

AU - Hautaniemi, Sampsa

AU - Lehti, Kaisa

AU - Ojala, Paivi M.

PY - 2018/5/1

Y1 - 2018/5/1

KW - TO-MESENCHYMAL TRANSITION

KW - TUMOR PROGRESSION

KW - NODE METASTASIS

KW - CELL-ADHESION

KW - CANCER

KW - METALLOPROTEINASES

KW - EXPRESSION

KW - PLATFORM

KW - VESSELS

KW - CCR7

KW - 3111 Biomedicine

U2 - 10.7554/eLife.32490

DO - 10.7554/eLife.32490

M3 - Article

VL - 7

JO - eLife

JF - eLife

SN - 2050-084X

M1 - 32490

ER -