Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export

Saskia Heybrock, Kristiina Kanerva, Ying Meng, Chris Ing, Anna Liang, Zi-Jian Xiong, Xialian Weng, Young Ah Kim, Richard Collins, William Trimble, Regis Pomes, Gilbert G. Prive, Wim Annaert, Michael Schwake, Joerg Heeren, Renate Lullmann-Rauch, Sergio Grinstein, Elina Ikonen, Paul Saftig, Dante Neculai

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
Article number3521
JournalNature Communications
Volume10
Number of pages12
ISSN2041-1723
DOIs
Publication statusPublished - 6 Aug 2019
MoE publication typeA1 Journal article-refereed

Fields of Science

  • MOLECULAR-DYNAMICS
  • DENSITY-LIPOPROTEIN
  • TRANSPORT
  • RECEPTOR
  • MECHANISMS
  • NPC1
  • CELL
  • TRAFFICKING
  • DEGRADATION
  • DEFICIENCY
  • 3111 Biomedicine

Cite this

Heybrock, Saskia ; Kanerva, Kristiina ; Meng, Ying ; Ing, Chris ; Liang, Anna ; Xiong, Zi-Jian ; Weng, Xialian ; Kim, Young Ah ; Collins, Richard ; Trimble, William ; Pomes, Regis ; Prive, Gilbert G. ; Annaert, Wim ; Schwake, Michael ; Heeren, Joerg ; Lullmann-Rauch, Renate ; Grinstein, Sergio ; Ikonen, Elina ; Saftig, Paul ; Neculai, Dante. / Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export. In: Nature Communications. 2019 ; Vol. 10.
@article{db92cef548fd4d2984352e592979de95,
title = "Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export",
keywords = "MOLECULAR-DYNAMICS, DENSITY-LIPOPROTEIN, TRANSPORT, RECEPTOR, MECHANISMS, NPC1, CELL, TRAFFICKING, DEGRADATION, DEFICIENCY, 3111 Biomedicine",
author = "Saskia Heybrock and Kristiina Kanerva and Ying Meng and Chris Ing and Anna Liang and Zi-Jian Xiong and Xialian Weng and Kim, {Young Ah} and Richard Collins and William Trimble and Regis Pomes and Prive, {Gilbert G.} and Wim Annaert and Michael Schwake and Joerg Heeren and Renate Lullmann-Rauch and Sergio Grinstein and Elina Ikonen and Paul Saftig and Dante Neculai",
year = "2019",
month = "8",
day = "6",
doi = "10.1038/s41467-019-11425-0",
language = "English",
volume = "10",
journal = "Nature Communications",
issn = "2041-1723",
publisher = "Nature Publishing Group",

}

Heybrock, S, Kanerva, K, Meng, Y, Ing, C, Liang, A, Xiong, Z-J, Weng, X, Kim, YA, Collins, R, Trimble, W, Pomes, R, Prive, GG, Annaert, W, Schwake, M, Heeren, J, Lullmann-Rauch, R, Grinstein, S, Ikonen, E, Saftig, P & Neculai, D 2019, 'Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export', Nature Communications, vol. 10, 3521. https://doi.org/10.1038/s41467-019-11425-0

Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export. / Heybrock, Saskia; Kanerva, Kristiina; Meng, Ying; Ing, Chris; Liang, Anna; Xiong, Zi-Jian; Weng, Xialian; Kim, Young Ah; Collins, Richard; Trimble, William; Pomes, Regis; Prive, Gilbert G.; Annaert, Wim; Schwake, Michael; Heeren, Joerg; Lullmann-Rauch, Renate; Grinstein, Sergio; Ikonen, Elina; Saftig, Paul; Neculai, Dante.

In: Nature Communications, Vol. 10, 3521, 06.08.2019.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export

AU - Heybrock, Saskia

AU - Kanerva, Kristiina

AU - Meng, Ying

AU - Ing, Chris

AU - Liang, Anna

AU - Xiong, Zi-Jian

AU - Weng, Xialian

AU - Kim, Young Ah

AU - Collins, Richard

AU - Trimble, William

AU - Pomes, Regis

AU - Prive, Gilbert G.

AU - Annaert, Wim

AU - Schwake, Michael

AU - Heeren, Joerg

AU - Lullmann-Rauch, Renate

AU - Grinstein, Sergio

AU - Ikonen, Elina

AU - Saftig, Paul

AU - Neculai, Dante

PY - 2019/8/6

Y1 - 2019/8/6

KW - MOLECULAR-DYNAMICS

KW - DENSITY-LIPOPROTEIN

KW - TRANSPORT

KW - RECEPTOR

KW - MECHANISMS

KW - NPC1

KW - CELL

KW - TRAFFICKING

KW - DEGRADATION

KW - DEFICIENCY

KW - 3111 Biomedicine

U2 - 10.1038/s41467-019-11425-0

DO - 10.1038/s41467-019-11425-0

M3 - Article

VL - 10

JO - Nature Communications

JF - Nature Communications

SN - 2041-1723

M1 - 3521

ER -