| Original language | English |
|---|---|
| Journal | Journal of Biological Chemistry |
| Volume | 294 |
| Issue number | 24 |
| Pages (from-to) | 9592-9604 |
| Number of pages | 13 |
| ISSN | 0021-9258 |
| DOIs | |
| Publication status | Published - 14 Jun 2019 |
| MoE publication type | A1 Journal article-refereed |
Fields of Science
- protein sorting
- trafficking
- lysosome
- neurodegenerative disease
- lipid droplet
- lipid metabolism
- endocytosis
- electron microscopy (EM)
- mannose 6-phosphate receptors
- pH regulation
- proteomics
- membrane protein
- NEURONAL-CEROID-LIPOFUSCINOSIS
- BATTEN-DISEASE GENE
- CLN3
- RECEPTOR
- BIOGENESIS
- PROTEINS
- BTN1
- DEPOSITION
- TRANSPORT
- PATHOLOGY
- 1182 Biochemistry, cell and molecular biology
Cite this
}
Lysosomal proteome analysis reveals that CLN3-defective cells have multiple enzyme deficiencies associated with changes in intracellular trafficking. / Schmidtke, Carolin; Tiede, Stephan; Thelen, Melanie; Käkelä, Reijo; Jabs, Sabrina; Makrypidi, Georgia; Sylvester, Marc; Schweizer, Michaela; Braren, Ingke; Brocke-Ahmadinejad, Nahal; Cotman, Susan L.; Schulz, Angela; Gieselmann, Volkmar; Braulke, Thomas.
In: Journal of Biological Chemistry, Vol. 294, No. 24, 14.06.2019, p. 9592-9604.Research output: Contribution to journal › Article › Scientific › peer-review
TY - JOUR
T1 - Lysosomal proteome analysis reveals that CLN3-defective cells have multiple enzyme deficiencies associated with changes in intracellular trafficking
AU - Schmidtke, Carolin
AU - Tiede, Stephan
AU - Thelen, Melanie
AU - Käkelä, Reijo
AU - Jabs, Sabrina
AU - Makrypidi, Georgia
AU - Sylvester, Marc
AU - Schweizer, Michaela
AU - Braren, Ingke
AU - Brocke-Ahmadinejad, Nahal
AU - Cotman, Susan L.
AU - Schulz, Angela
AU - Gieselmann, Volkmar
AU - Braulke, Thomas
PY - 2019/6/14
Y1 - 2019/6/14
KW - protein sorting
KW - trafficking
KW - lysosome
KW - neurodegenerative disease
KW - lipid droplet
KW - lipid metabolism
KW - endocytosis
KW - electron microscopy (EM)
KW - mannose 6-phosphate receptors
KW - pH regulation
KW - proteomics
KW - membrane protein
KW - NEURONAL-CEROID-LIPOFUSCINOSIS
KW - BATTEN-DISEASE GENE
KW - CLN3
KW - RECEPTOR
KW - BIOGENESIS
KW - PROTEINS
KW - BTN1
KW - DEPOSITION
KW - TRANSPORT
KW - PATHOLOGY
KW - 1182 Biochemistry, cell and molecular biology
U2 - 10.1074/jbc.RA119.008852
DO - 10.1074/jbc.RA119.008852
M3 - Article
VL - 294
SP - 9592
EP - 9604
JO - Journal of Biological Chemistry
JF - Journal of Biological Chemistry
SN - 0021-9258
IS - 24
ER -