MANF protects human pancreatic beta cells against stress-induced cell death

Elina Hakonen, Vikash Chandra, Christopher L. Fogarty, Nancy Yiu-Lin Yu, Jarkko Ustinov, Shintaro Katayama, Emilia Galli, Tatiana Danilova, Paivi Lindholm, Aki Vartiainen, Elisabet Einarsdottir, Kaarel Krjutskov, Juha Kere, Mart Saarma, Maria Lindahl, Timo Otonkoski

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalDiabetologia
Volume61
Issue number10
Pages (from-to)2202-2214
Number of pages13
ISSN0012-186X
DOIs
Publication statusPublished - Oct 2018
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Beta cell proliferation
  • Beta cell protection
  • Endoplasmic reticulum stress
  • Mesencephalic astrocyte-derived neurotrophic factor (MANF)
  • NF-kappa B
  • NF-KAPPA-B
  • ENDOPLASMIC-RETICULUM STRESS
  • NEUROTROPHIC FACTOR MANF
  • DIFFERENTIAL EXPRESSION
  • INSULIN-SECRETION
  • ER STRESS
  • TYPE-1
  • PROLIFERATION
  • TRANSCRIPTOME
  • NORMALIZATION
  • 3121 Internal medicine

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