Abstract

Background. Previous studies have linked maternal obesity with depressive symptoms during and after pregnancy. It remains unknown whether obesity associates with consistently elevated depressive symptoms throughout pregnancy, predicts symptoms postpartum when accounting for antenatal symptoms, and if co-morbid hypertensive and diabetic disorders add to these associations. We addressed these questions in a sample of Finnish women whom we followed during and after pregnancy.

Methods. Early pregnancy body mass index, derived from the Finnish Medical Birth Register and hospital records in 3234 PREDO study participants, was categorized into underweight (= 30 kg/m(2)) groups. The women completed the Center for Epidemiological Studies Depression Scale biweekly during pregnancy, and at 2.4 (S.D. = 1.2) and/or 28.2 (S.D. = 4.2) weeks after pregnancy.

Results. In comparison to normal weight women, overweight, and obese women reported higher levels of depressive symptoms and had higher odds of clinically significant depressive symptoms during (23% and 43%, respectively) and after pregnancy (22% and 36%, respectively). Underweight women had 68% higher odds of clinically significant depressive symptoms after pregnancy. Overweight and obesity also predicted higher depressive symptoms after pregnancy in women not reporting clinically relevant symptomatology during pregnancy. Hypertensive and diabetic disorders did not explain or add to these associations.

Conclusions. Maternal early pregnancy overweight and obesity and depressive symptoms during and after pregnancy are associated. Mental health promotion should be included as an integral part of lifestyle interventions in early pregnancy obesity and extended to benefit also overweight and underweight women.

Original languageEnglish
JournalPsychological Medicine
Volume48
Issue number14
Pages (from-to)2353-2363
Number of pages11
ISSN0033-2917
DOIs
Publication statusPublished - Oct 2018
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Antenatal depression
  • early pregnancy body mass index
  • postpartum depression
  • pregnancy disorders
  • BODY-MASS INDEX
  • GESTATIONAL WEIGHT-GAIN
  • PITUITARY-ADRENAL AXIS
  • QUALITY-OF-LIFE
  • POSTPARTUM DEPRESSION
  • ANTENATAL DEPRESSION
  • DNA METHYLATION
  • PREPREGNANCY OBESITY
  • META-ANALYSIS
  • WOMEN
  • 515 Psychology

Cite this

@article{71da376903c74ca89f54b4def937581d,
title = "Maternal early pregnancy obesity and depressive symptoms during and after pregnancy.",
abstract = "Background. Previous studies have linked maternal obesity with depressive symptoms during and after pregnancy. It remains unknown whether obesity associates with consistently elevated depressive symptoms throughout pregnancy, predicts symptoms postpartum when accounting for antenatal symptoms, and if co-morbid hypertensive and diabetic disorders add to these associations. We addressed these questions in a sample of Finnish women whom we followed during and after pregnancy.Methods. Early pregnancy body mass index, derived from the Finnish Medical Birth Register and hospital records in 3234 PREDO study participants, was categorized into underweight (= 30 kg/m(2)) groups. The women completed the Center for Epidemiological Studies Depression Scale biweekly during pregnancy, and at 2.4 (S.D. = 1.2) and/or 28.2 (S.D. = 4.2) weeks after pregnancy.Results. In comparison to normal weight women, overweight, and obese women reported higher levels of depressive symptoms and had higher odds of clinically significant depressive symptoms during (23{\%} and 43{\%}, respectively) and after pregnancy (22{\%} and 36{\%}, respectively). Underweight women had 68{\%} higher odds of clinically significant depressive symptoms after pregnancy. Overweight and obesity also predicted higher depressive symptoms after pregnancy in women not reporting clinically relevant symptomatology during pregnancy. Hypertensive and diabetic disorders did not explain or add to these associations.Conclusions. Maternal early pregnancy overweight and obesity and depressive symptoms during and after pregnancy are associated. Mental health promotion should be included as an integral part of lifestyle interventions in early pregnancy obesity and extended to benefit also overweight and underweight women.",
keywords = "Antenatal depression, early pregnancy body mass index, postpartum depression, pregnancy disorders, BODY-MASS INDEX, GESTATIONAL WEIGHT-GAIN, PITUITARY-ADRENAL AXIS, QUALITY-OF-LIFE, POSTPARTUM DEPRESSION, ANTENATAL DEPRESSION, DNA METHYLATION, PREPREGNANCY OBESITY, META-ANALYSIS, WOMEN, 515 Psychology",
author = "Kumpulainen, {Satu M.} and Polina Girchenko and Marius Lahti-Pulkkinen and Reynolds, {Rebecca M.} and Soile Tuovinen and Anu-Katriina Pesonen and Kati Heinonen and Eero Kajantie and Villa, {Pia M.} and Esa H{\"a}m{\"a}l{\"a}inen and Hannele Laivuori and Katri R{\"a}ikk{\"o}nen",
year = "2018",
month = "10",
doi = "10.1017/S0033291717003889",
language = "English",
volume = "48",
pages = "2353--2363",
journal = "Psychological Medicine",
issn = "0033-2917",
publisher = "Cambridge University Press",
number = "14",

}

TY - JOUR

T1 - Maternal early pregnancy obesity and depressive symptoms during and after pregnancy.

AU - Kumpulainen, Satu M.

AU - Girchenko, Polina

AU - Lahti-Pulkkinen, Marius

AU - Reynolds, Rebecca M.

AU - Tuovinen, Soile

AU - Pesonen, Anu-Katriina

AU - Heinonen, Kati

AU - Kajantie, Eero

AU - Villa, Pia M.

AU - Hämäläinen, Esa

AU - Laivuori, Hannele

AU - Räikkönen, Katri

PY - 2018/10

Y1 - 2018/10

N2 - Background. Previous studies have linked maternal obesity with depressive symptoms during and after pregnancy. It remains unknown whether obesity associates with consistently elevated depressive symptoms throughout pregnancy, predicts symptoms postpartum when accounting for antenatal symptoms, and if co-morbid hypertensive and diabetic disorders add to these associations. We addressed these questions in a sample of Finnish women whom we followed during and after pregnancy.Methods. Early pregnancy body mass index, derived from the Finnish Medical Birth Register and hospital records in 3234 PREDO study participants, was categorized into underweight (= 30 kg/m(2)) groups. The women completed the Center for Epidemiological Studies Depression Scale biweekly during pregnancy, and at 2.4 (S.D. = 1.2) and/or 28.2 (S.D. = 4.2) weeks after pregnancy.Results. In comparison to normal weight women, overweight, and obese women reported higher levels of depressive symptoms and had higher odds of clinically significant depressive symptoms during (23% and 43%, respectively) and after pregnancy (22% and 36%, respectively). Underweight women had 68% higher odds of clinically significant depressive symptoms after pregnancy. Overweight and obesity also predicted higher depressive symptoms after pregnancy in women not reporting clinically relevant symptomatology during pregnancy. Hypertensive and diabetic disorders did not explain or add to these associations.Conclusions. Maternal early pregnancy overweight and obesity and depressive symptoms during and after pregnancy are associated. Mental health promotion should be included as an integral part of lifestyle interventions in early pregnancy obesity and extended to benefit also overweight and underweight women.

AB - Background. Previous studies have linked maternal obesity with depressive symptoms during and after pregnancy. It remains unknown whether obesity associates with consistently elevated depressive symptoms throughout pregnancy, predicts symptoms postpartum when accounting for antenatal symptoms, and if co-morbid hypertensive and diabetic disorders add to these associations. We addressed these questions in a sample of Finnish women whom we followed during and after pregnancy.Methods. Early pregnancy body mass index, derived from the Finnish Medical Birth Register and hospital records in 3234 PREDO study participants, was categorized into underweight (= 30 kg/m(2)) groups. The women completed the Center for Epidemiological Studies Depression Scale biweekly during pregnancy, and at 2.4 (S.D. = 1.2) and/or 28.2 (S.D. = 4.2) weeks after pregnancy.Results. In comparison to normal weight women, overweight, and obese women reported higher levels of depressive symptoms and had higher odds of clinically significant depressive symptoms during (23% and 43%, respectively) and after pregnancy (22% and 36%, respectively). Underweight women had 68% higher odds of clinically significant depressive symptoms after pregnancy. Overweight and obesity also predicted higher depressive symptoms after pregnancy in women not reporting clinically relevant symptomatology during pregnancy. Hypertensive and diabetic disorders did not explain or add to these associations.Conclusions. Maternal early pregnancy overweight and obesity and depressive symptoms during and after pregnancy are associated. Mental health promotion should be included as an integral part of lifestyle interventions in early pregnancy obesity and extended to benefit also overweight and underweight women.

KW - Antenatal depression

KW - early pregnancy body mass index

KW - postpartum depression

KW - pregnancy disorders

KW - BODY-MASS INDEX

KW - GESTATIONAL WEIGHT-GAIN

KW - PITUITARY-ADRENAL AXIS

KW - QUALITY-OF-LIFE

KW - POSTPARTUM DEPRESSION

KW - ANTENATAL DEPRESSION

KW - DNA METHYLATION

KW - PREPREGNANCY OBESITY

KW - META-ANALYSIS

KW - WOMEN

KW - 515 Psychology

U2 - 10.1017/S0033291717003889

DO - 10.1017/S0033291717003889

M3 - Article

VL - 48

SP - 2353

EP - 2363

JO - Psychological Medicine

JF - Psychological Medicine

SN - 0033-2917

IS - 14

ER -