Mcl-1 and Bok transmembrane domains: Unexpected players in the modulation of apoptosis

Estefania Lucendo; Monica Sancho; Fabio Lolicato; Matti Javanainen; Waldemar Kulig; Diego Leiva; Gerard Duart; Vicente Andreu-Fernandez; Ismael Mingarro; Mar Orzaez

doi:10.1073/pnas.2008885117

Mcl-1 and Bok transmembrane domains: Unexpected players in the modulation of apoptosis

Estefania Lucendo, Monica Sancho, Fabio Lolicato, Matti Javanainen, Waldemar Kulig, Diego Leiva, Gerard Duart, Vicente Andreu-Fernandez, Ismael Mingarro, Mar Orzaez

Department of Physics

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Proceedings of the National Academy of Sciences of the United States of America
Volume	117
Issue number	45
Pages (from-to)	27980-27988
Number of pages	9
ISSN	0027-8424
DOIs	https://doi.org/10.1073/pnas.2008885117
Publication status	Published - 10 Nov 2020
MoE publication type	A1 Journal article-refereed

Fields of Science

apoptosis
Bcl-2
Bok
Mcl-1
transmembrane
PROSURVIVAL BCL-2 PROTEINS
GLYCOPHORIN-A DIMERIZATION
HELIX PACKING
BAX
BCL-X(L)
MOTIF
LOCALIZATION
MITOCHONDRIA
PATHWAYS
SURVIVAL
1182 Biochemistry, cell and molecular biology
114 Physical sciences

Access to Document

10.1073/pnas.2008885117

submissionAccepted author manuscript, 1.87 MB

Cite this

Lucendo, E., Sancho, M., Lolicato, F., Javanainen, M., Kulig, W., Leiva, D., Duart, G., Andreu-Fernandez, V., Mingarro, I., & Orzaez, M. (2020). Mcl-1 and Bok transmembrane domains: Unexpected players in the modulation of apoptosis. Proceedings of the National Academy of Sciences of the United States of America, 117(45), 27980-27988. https://doi.org/10.1073/pnas.2008885117

Lucendo, Estefania ; Sancho, Monica ; Lolicato, Fabio ; Javanainen, Matti ; Kulig, Waldemar ; Leiva, Diego ; Duart, Gerard ; Andreu-Fernandez, Vicente ; Mingarro, Ismael ; Orzaez, Mar. / Mcl-1 and Bok transmembrane domains : Unexpected players in the modulation of apoptosis. In: Proceedings of the National Academy of Sciences of the United States of America. 2020 ; Vol. 117, No. 45. pp. 27980-27988.

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title = "Mcl-1 and Bok transmembrane domains: Unexpected players in the modulation of apoptosis",

keywords = "apoptosis, Bcl-2, Bok, Mcl-1, transmembrane, PROSURVIVAL BCL-2 PROTEINS, GLYCOPHORIN-A DIMERIZATION, HELIX PACKING, BAX, BCL-X(L), MOTIF, LOCALIZATION, MITOCHONDRIA, PATHWAYS, SURVIVAL, 1182 Biochemistry, cell and molecular biology, 114 Physical sciences",

author = "Estefania Lucendo and Monica Sancho and Fabio Lolicato and Matti Javanainen and Waldemar Kulig and Diego Leiva and Gerard Duart and Vicente Andreu-Fernandez and Ismael Mingarro and Mar Orzaez",

year = "2020",

month = nov,

day = "10",

doi = "10.1073/pnas.2008885117",

language = "English",

volume = "117",

pages = "27980--27988",

journal = "Proceedings of the National Academy of Sciences of the United States of America",

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Lucendo, E, Sancho, M, Lolicato, F, Javanainen, M, Kulig, W, Leiva, D, Duart, G, Andreu-Fernandez, V, Mingarro, I & Orzaez, M 2020, 'Mcl-1 and Bok transmembrane domains: Unexpected players in the modulation of apoptosis', Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 45, pp. 27980-27988. https://doi.org/10.1073/pnas.2008885117

Mcl-1 and Bok transmembrane domains : Unexpected players in the modulation of apoptosis. / Lucendo, Estefania; Sancho, Monica; Lolicato, Fabio; Javanainen, Matti; Kulig, Waldemar; Leiva, Diego; Duart, Gerard; Andreu-Fernandez, Vicente; Mingarro, Ismael; Orzaez, Mar.

In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, No. 45, 10.11.2020, p. 27980-27988.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Mcl-1 and Bok transmembrane domains

T2 - Unexpected players in the modulation of apoptosis

AU - Lucendo, Estefania

AU - Sancho, Monica

AU - Lolicato, Fabio

AU - Javanainen, Matti

AU - Kulig, Waldemar

AU - Leiva, Diego

AU - Duart, Gerard

AU - Andreu-Fernandez, Vicente

AU - Mingarro, Ismael

AU - Orzaez, Mar

PY - 2020/11/10

Y1 - 2020/11/10

KW - apoptosis

KW - Bcl-2

KW - Bok

KW - Mcl-1

KW - transmembrane

KW - PROSURVIVAL BCL-2 PROTEINS

KW - GLYCOPHORIN-A DIMERIZATION

KW - HELIX PACKING

KW - BAX

KW - BCL-X(L)

KW - MOTIF

KW - LOCALIZATION

KW - MITOCHONDRIA

KW - PATHWAYS

KW - SURVIVAL

KW - 1182 Biochemistry, cell and molecular biology

KW - 114 Physical sciences

U2 - 10.1073/pnas.2008885117

DO - 10.1073/pnas.2008885117

M3 - Article

VL - 117

SP - 27980

EP - 27988

JO - Proceedings of the National Academy of Sciences of the United States of America

JF - Proceedings of the National Academy of Sciences of the United States of America

SN - 0027-8424

IS - 45

ER -