Mechanisms of Pathogenicity in Human MSH2 Missense Mutants

    Research output: Contribution to journalArticleScientificpeer-review

    Original languageEnglish
    JournalHuman Mutation
    Volume29
    Issue number11
    Pages (from-to)1355-1363
    Number of pages9
    ISSN1059-7794
    DOIs
    Publication statusPublished - 2008
    MoE publication typeA1 Journal article-refereed

    Fields of Science

    • mismatch repair
    • MMR
    • hereditary nonpolyposis colorectal cancer
    • HNPCC
    • MSH2
    • functional analysis
    • NONPOLYPOSIS COLORECTAL-CANCER
    • MISMATCH REPAIR GENES
    • LYNCH-SYNDROME
    • MICROSATELLITE INSTABILITY
    • HMUTS-ALPHA
    • TRANSLOCATION MECHANISM
    • RECOGNITION COMPLEX
    • FUNCTIONAL-ANALYSIS
    • MOLECULAR SWITCH
    • ATPASE ACTIVITY
    • 118 Biological sciences

    Cite this

    @article{ebd6d38eac5644dd9470ce4f4c0829af,
    title = "Mechanisms of Pathogenicity in Human MSH2 Missense Mutants",
    keywords = "mismatch repair, MMR, hereditary nonpolyposis colorectal cancer, HNPCC, MSH2, functional analysis, NONPOLYPOSIS COLORECTAL-CANCER, MISMATCH REPAIR GENES, LYNCH-SYNDROME, MICROSATELLITE INSTABILITY, HMUTS-ALPHA, TRANSLOCATION MECHANISM, RECOGNITION COMPLEX, FUNCTIONAL-ANALYSIS, MOLECULAR SWITCH, ATPASE ACTIVITY, 118 Biological sciences",
    author = "Saara Ollila and {Dermadi Bebek}, Denis and Josef Jiricny and Minna Nystr{\"o}m",
    year = "2008",
    doi = "10.1002/humu.20893",
    language = "English",
    volume = "29",
    pages = "1355--1363",
    journal = "Human Mutation",
    issn = "1059-7794",
    publisher = "John Wiley & Sons, Ltd",
    number = "11",

    }

    Mechanisms of Pathogenicity in Human MSH2 Missense Mutants. / Ollila, Saara; Dermadi Bebek, Denis; Jiricny, Josef; Nyström, Minna.

    In: Human Mutation, Vol. 29, No. 11, 2008, p. 1355-1363.

    Research output: Contribution to journalArticleScientificpeer-review

    TY - JOUR

    T1 - Mechanisms of Pathogenicity in Human MSH2 Missense Mutants

    AU - Ollila, Saara

    AU - Dermadi Bebek, Denis

    AU - Jiricny, Josef

    AU - Nyström, Minna

    PY - 2008

    Y1 - 2008

    KW - mismatch repair

    KW - MMR

    KW - hereditary nonpolyposis colorectal cancer

    KW - HNPCC

    KW - MSH2

    KW - functional analysis

    KW - NONPOLYPOSIS COLORECTAL-CANCER

    KW - MISMATCH REPAIR GENES

    KW - LYNCH-SYNDROME

    KW - MICROSATELLITE INSTABILITY

    KW - HMUTS-ALPHA

    KW - TRANSLOCATION MECHANISM

    KW - RECOGNITION COMPLEX

    KW - FUNCTIONAL-ANALYSIS

    KW - MOLECULAR SWITCH

    KW - ATPASE ACTIVITY

    KW - 118 Biological sciences

    U2 - 10.1002/humu.20893

    DO - 10.1002/humu.20893

    M3 - Article

    VL - 29

    SP - 1355

    EP - 1363

    JO - Human Mutation

    JF - Human Mutation

    SN - 1059-7794

    IS - 11

    ER -