Melt-electrospinning as a method to improve the dissolution and physical stability of a poorly water-soluble drug

Kristian Semjonov, Andres Lust, Karin Kogermann, Ivo Laidmäe, Sirkka Liisa Maunu, Sami-Pekka Hirvonen, Jouko Yliruusi, Gunnar Nurk, Enn Lust, Jyrki Heinamäki

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalEuropean Journal of Pharmaceutical Sciences
Volume121
Pages (from-to)260-268
Number of pages9
ISSN0928-0987
DOIs
Publication statusPublished - 30 Aug 2018
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Melt electrospinning
  • Melt-spun fibers
  • Poorly water-soluble drug
  • Indomethacin
  • Soluplus (R)
  • Drug-polymer interactions
  • AMORPHOUS SOLID DISPERSIONS
  • ORAL BIOAVAILABILITY
  • POLYMER MISCIBILITY
  • STARCH ACETATES
  • DOSAGE FORMS
  • INDOMETHACIN
  • STATE
  • SOLUBILITY
  • EXTRUSION
  • SOLUPLUS(R)
  • 317 Pharmacy
  • 116 Chemical sciences

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