Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

Padhraig Gormley, Verneri Anttila, Bendik S. Winsvold, Priit Palta, Tonu Esko, Tune H. Pers, Kai-How Farh, Ester Cuenca-Leon, Mikko Muona, Nicholas A. Furlotte, Tobias Kurth, Andres Ingason, George McMahon, Lannie Ligthart, Gisela M. Terwindt, Mikko Kallela, Tobias M. Freilinger, Caroline Ran, Scott G. Gordon, Anine H. Stam & 32 others Stacy Steinberg, Guntram Borck, Markku Koiranen, Lydia Quaye, Hieab H. H. Adams, Terho Lehtimaki, Antti-Pekka Sarin, Juho Wedenoja, David A. Hinds, Julie E. Buring, Markus Schurks, Paul M. Ridker, Maria Gudlaug Hrafnsdottir, Hreinn Stefansson, Susan M. Ring, Jouke-Jan Hottenga, Brenda W. J. H. Penninx, Markus Färkkilä, Ville Artto, Mari Kaunisto, Salli Vepsalainen, Rainer Malik, Andrew C. Heath, Kalle Pärn, Eija Hämäläinen, Johan G. Eriksson, Kauko Heikkila, Jaakko Kaprio, Maija Wessman, Mark J. Daly, Aarno Palotie, Int Headache Genetics Consortium

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalNature Genetics
Volume48
Issue number8
Pages (from-to)856-+
Number of pages14
ISSN1061-4036
DOIs
Publication statusPublished - Aug 2016
MoE publication typeA1 Journal article-refereed

Fields of Science

  • GENOME-WIDE ASSOCIATION
  • FAMILIAL HEMIPLEGIC MIGRAINE
  • SINGLE-NUCLEOTIDE POLYMORPHISMS
  • RECEPTOR-RELATED PROTEIN-1
  • SMOOTH-MUSCLE-CELLS
  • GENE-EXPRESSION
  • MYOCARDIAL-INFARCTION
  • SPREADING DEPRESSION
  • GENOTYPE IMPUTATION
  • SYSTEMATIC ANALYSIS
  • 3111 Biomedicine

Cite this

Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T., Pers, T. H., ... Int Headache Genetics Consortium (2016). Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine. Nature Genetics, 48(8), 856-+. https://doi.org/10.1038/ng.3598
Gormley, Padhraig ; Anttila, Verneri ; Winsvold, Bendik S. ; Palta, Priit ; Esko, Tonu ; Pers, Tune H. ; Farh, Kai-How ; Cuenca-Leon, Ester ; Muona, Mikko ; Furlotte, Nicholas A. ; Kurth, Tobias ; Ingason, Andres ; McMahon, George ; Ligthart, Lannie ; Terwindt, Gisela M. ; Kallela, Mikko ; Freilinger, Tobias M. ; Ran, Caroline ; Gordon, Scott G. ; Stam, Anine H. ; Steinberg, Stacy ; Borck, Guntram ; Koiranen, Markku ; Quaye, Lydia ; Adams, Hieab H. H. ; Lehtimaki, Terho ; Sarin, Antti-Pekka ; Wedenoja, Juho ; Hinds, David A. ; Buring, Julie E. ; Schurks, Markus ; Ridker, Paul M. ; Hrafnsdottir, Maria Gudlaug ; Stefansson, Hreinn ; Ring, Susan M. ; Hottenga, Jouke-Jan ; Penninx, Brenda W. J. H. ; Färkkilä, Markus ; Artto, Ville ; Kaunisto, Mari ; Vepsalainen, Salli ; Malik, Rainer ; Heath, Andrew C. ; Pärn, Kalle ; Hämäläinen, Eija ; Eriksson, Johan G. ; Heikkila, Kauko ; Kaprio, Jaakko ; Wessman, Maija ; Daly, Mark J. ; Palotie, Aarno ; Int Headache Genetics Consortium. / Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine. In: Nature Genetics. 2016 ; Vol. 48, No. 8. pp. 856-+.
@article{bd96c6168032426c9953f4481d2ac048,
title = "Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine",
keywords = "GENOME-WIDE ASSOCIATION, FAMILIAL HEMIPLEGIC MIGRAINE, SINGLE-NUCLEOTIDE POLYMORPHISMS, RECEPTOR-RELATED PROTEIN-1, SMOOTH-MUSCLE-CELLS, GENE-EXPRESSION, MYOCARDIAL-INFARCTION, SPREADING DEPRESSION, GENOTYPE IMPUTATION, SYSTEMATIC ANALYSIS, 3111 Biomedicine",
author = "Padhraig Gormley and Verneri Anttila and Winsvold, {Bendik S.} and Priit Palta and Tonu Esko and Pers, {Tune H.} and Kai-How Farh and Ester Cuenca-Leon and Mikko Muona and Furlotte, {Nicholas A.} and Tobias Kurth and Andres Ingason and George McMahon and Lannie Ligthart and Terwindt, {Gisela M.} and Mikko Kallela and Freilinger, {Tobias M.} and Caroline Ran and Gordon, {Scott G.} and Stam, {Anine H.} and Stacy Steinberg and Guntram Borck and Markku Koiranen and Lydia Quaye and Adams, {Hieab H. H.} and Terho Lehtimaki and Antti-Pekka Sarin and Juho Wedenoja and Hinds, {David A.} and Buring, {Julie E.} and Markus Schurks and Ridker, {Paul M.} and Hrafnsdottir, {Maria Gudlaug} and Hreinn Stefansson and Ring, {Susan M.} and Jouke-Jan Hottenga and Penninx, {Brenda W. J. H.} and Markus F{\"a}rkkil{\"a} and Ville Artto and Mari Kaunisto and Salli Vepsalainen and Rainer Malik and Heath, {Andrew C.} and Kalle P{\"a}rn and Eija H{\"a}m{\"a}l{\"a}inen and Eriksson, {Johan G.} and Kauko Heikkila and Jaakko Kaprio and Maija Wessman and Daly, {Mark J.} and Aarno Palotie and {Int Headache Genetics Consortium}",
year = "2016",
month = "8",
doi = "10.1038/ng.3598",
language = "English",
volume = "48",
pages = "856--+",
journal = "Nature Genetics",
issn = "1061-4036",
publisher = "Nature Publishing Group",
number = "8",

}

Gormley, P, Anttila, V, Winsvold, BS, Palta, P, Esko, T, Pers, TH, Farh, K-H, Cuenca-Leon, E, Muona, M, Furlotte, NA, Kurth, T, Ingason, A, McMahon, G, Ligthart, L, Terwindt, GM, Kallela, M, Freilinger, TM, Ran, C, Gordon, SG, Stam, AH, Steinberg, S, Borck, G, Koiranen, M, Quaye, L, Adams, HHH, Lehtimaki, T, Sarin, A-P, Wedenoja, J, Hinds, DA, Buring, JE, Schurks, M, Ridker, PM, Hrafnsdottir, MG, Stefansson, H, Ring, SM, Hottenga, J-J, Penninx, BWJH, Färkkilä, M, Artto, V, Kaunisto, M, Vepsalainen, S, Malik, R, Heath, AC, Pärn, K, Hämäläinen, E, Eriksson, JG, Heikkila, K, Kaprio, J, Wessman, M, Daly, MJ, Palotie, A & Int Headache Genetics Consortium 2016, 'Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine', Nature Genetics, vol. 48, no. 8, pp. 856-+. https://doi.org/10.1038/ng.3598

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine. / Gormley, Padhraig; Anttila, Verneri; Winsvold, Bendik S.; Palta, Priit; Esko, Tonu; Pers, Tune H.; Farh, Kai-How; Cuenca-Leon, Ester; Muona, Mikko; Furlotte, Nicholas A.; Kurth, Tobias; Ingason, Andres; McMahon, George; Ligthart, Lannie; Terwindt, Gisela M.; Kallela, Mikko; Freilinger, Tobias M.; Ran, Caroline; Gordon, Scott G.; Stam, Anine H.; Steinberg, Stacy; Borck, Guntram; Koiranen, Markku; Quaye, Lydia; Adams, Hieab H. H.; Lehtimaki, Terho; Sarin, Antti-Pekka; Wedenoja, Juho; Hinds, David A.; Buring, Julie E.; Schurks, Markus; Ridker, Paul M.; Hrafnsdottir, Maria Gudlaug; Stefansson, Hreinn; Ring, Susan M.; Hottenga, Jouke-Jan; Penninx, Brenda W. J. H.; Färkkilä, Markus; Artto, Ville; Kaunisto, Mari; Vepsalainen, Salli; Malik, Rainer; Heath, Andrew C.; Pärn, Kalle; Hämäläinen, Eija; Eriksson, Johan G.; Heikkila, Kauko; Kaprio, Jaakko; Wessman, Maija; Daly, Mark J.; Palotie, Aarno; Int Headache Genetics Consortium.

In: Nature Genetics, Vol. 48, No. 8, 08.2016, p. 856-+.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

AU - Gormley, Padhraig

AU - Anttila, Verneri

AU - Winsvold, Bendik S.

AU - Palta, Priit

AU - Esko, Tonu

AU - Pers, Tune H.

AU - Farh, Kai-How

AU - Cuenca-Leon, Ester

AU - Muona, Mikko

AU - Furlotte, Nicholas A.

AU - Kurth, Tobias

AU - Ingason, Andres

AU - McMahon, George

AU - Ligthart, Lannie

AU - Terwindt, Gisela M.

AU - Kallela, Mikko

AU - Freilinger, Tobias M.

AU - Ran, Caroline

AU - Gordon, Scott G.

AU - Stam, Anine H.

AU - Steinberg, Stacy

AU - Borck, Guntram

AU - Koiranen, Markku

AU - Quaye, Lydia

AU - Adams, Hieab H. H.

AU - Lehtimaki, Terho

AU - Sarin, Antti-Pekka

AU - Wedenoja, Juho

AU - Hinds, David A.

AU - Buring, Julie E.

AU - Schurks, Markus

AU - Ridker, Paul M.

AU - Hrafnsdottir, Maria Gudlaug

AU - Stefansson, Hreinn

AU - Ring, Susan M.

AU - Hottenga, Jouke-Jan

AU - Penninx, Brenda W. J. H.

AU - Färkkilä, Markus

AU - Artto, Ville

AU - Kaunisto, Mari

AU - Vepsalainen, Salli

AU - Malik, Rainer

AU - Heath, Andrew C.

AU - Pärn, Kalle

AU - Hämäläinen, Eija

AU - Eriksson, Johan G.

AU - Heikkila, Kauko

AU - Kaprio, Jaakko

AU - Wessman, Maija

AU - Daly, Mark J.

AU - Palotie, Aarno

AU - Int Headache Genetics Consortium

PY - 2016/8

Y1 - 2016/8

KW - GENOME-WIDE ASSOCIATION

KW - FAMILIAL HEMIPLEGIC MIGRAINE

KW - SINGLE-NUCLEOTIDE POLYMORPHISMS

KW - RECEPTOR-RELATED PROTEIN-1

KW - SMOOTH-MUSCLE-CELLS

KW - GENE-EXPRESSION

KW - MYOCARDIAL-INFARCTION

KW - SPREADING DEPRESSION

KW - GENOTYPE IMPUTATION

KW - SYSTEMATIC ANALYSIS

KW - 3111 Biomedicine

U2 - 10.1038/ng.3598

DO - 10.1038/ng.3598

M3 - Article

VL - 48

SP - 856-+

JO - Nature Genetics

JF - Nature Genetics

SN - 1061-4036

IS - 8

ER -