Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels

Elisabeth M. van Leeuwen, Aniko Sabo, Joshua C. Bis, Jennifer E. Huffman, Ani Manichaikul, Albert V. Smith, Mary F. Feitosa, Serkalem Demissie, Peter K. Joshi, Qing Duan, Jonathan Marten, Jan B. van Klinken, Ida Surakka, Ilja M. Nolte, Weihua Zhang, Hamdi Mbarek, Ruifang Li-Gao, Stella Trompet, Niek Verweij, Evangelos EvangelouLeo-Pekka Lyytikainen, Bamidele O. Tayo, Joris Deelen, Peter J. van der Most, Sander W. van der Laan, Dan E. Arking, Alanna Morrison, Abbas Dehghan, Oscar H. Franco, Albert Hofman, Fernando Rivadeneira, Eric J. Sijbrands, Andre G. Uitterlinden, Josyf C. Mychaleckyj, Archie Campbell, Lynne J. Hocking, Sandosh Padmanabhan, Jennifer A. Brody, Kenneth M. Rice, Charles C. White, Tamara Harris, Aaron Isaacs, Harry Campbell, Leslie A. Lange, Igor Rudan, Ivana Kolcic, Pau Navarro, Tatijana Zemunik, Veikko Salomaa, Samuli Ripatti, CHARGE Lipids Working Grp

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalJournal of Medical Genetics
Volume53
Issue number7
Pages (from-to)441-449
Number of pages9
ISSN0022-2593
DOIs
Publication statusPublished - Jul 2016
MoE publication typeA1 Journal article-refereed

Fields of Science

  • ELEMENT-BINDING PROTEIN
  • GENE-EXPRESSION
  • LIPID-SYNTHESIS
  • GLUCOSE
  • CHREBP
  • MUTATIONS
  • TRIGLYCERIDES
  • TRANSCRIPTION
  • SREBP-1C
  • DISEASE
  • 1184 Genetics, developmental biology, physiology
  • 3142 Public health care science, environmental and occupational health

Cite this