Metabolic Signatures of Adiposity in Young Adults: Mendelian Randomization Analysis and Effects of Weight Change

Peter Würtz, Qin Wang, Antti J. Kangas, Rebecca C. Richmond, Joni Skarp, Mika Tiainen, Tuulia Tynkkynen, Pasi Soininen, Aki S. Havulinna, Marika Kaakinen, Jorma S. Viikari, Markku J. Savolainen, Mika Kahonen, Terho Lehtimaki, Satu Mannisto, Stefan Blankenberg, Tanja Zeller, Jaana Laitinen, Anneli Pouta, Pekka MantyselkaMauno Vanhala, Paul Elliott, Kirsi H. Pietilainen, Samuli Ripatti, Veikko Salomaa, Olli T. Raitakari, Marjo-Riitta Jarvelin, George Davey Smith, Mika Ala-Korpela

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
Article number1001765
JournalPLoS Medicine
Volume11
Issue number12
Number of pages18
ISSN1549-1676
DOIs
Publication statusPublished - Dec 2014
MoE publication typeA1 Journal article-refereed

Fields of Science

  • BODY-MASS INDEX
  • AMERICAN-HEART-ASSOCIATION
  • GENOME-WIDE ASSOCIATION
  • PHYSICAL-ACTIVITY
  • CARDIOVASCULAR RISK
  • INSULIN-RESISTANCE
  • OBESITY
  • OVERWEIGHT
  • MORTALITY
  • COHORT
  • 3142 Public health care science, environmental and occupational health
  • 3121 Internal medicine

Cite this

Würtz, Peter ; Wang, Qin ; Kangas, Antti J. ; Richmond, Rebecca C. ; Skarp, Joni ; Tiainen, Mika ; Tynkkynen, Tuulia ; Soininen, Pasi ; Havulinna, Aki S. ; Kaakinen, Marika ; Viikari, Jorma S. ; Savolainen, Markku J. ; Kahonen, Mika ; Lehtimaki, Terho ; Mannisto, Satu ; Blankenberg, Stefan ; Zeller, Tanja ; Laitinen, Jaana ; Pouta, Anneli ; Mantyselka, Pekka ; Vanhala, Mauno ; Elliott, Paul ; Pietilainen, Kirsi H. ; Ripatti, Samuli ; Salomaa, Veikko ; Raitakari, Olli T. ; Jarvelin, Marjo-Riitta ; Smith, George Davey ; Ala-Korpela, Mika. / Metabolic Signatures of Adiposity in Young Adults : Mendelian Randomization Analysis and Effects of Weight Change. In: PLoS Medicine. 2014 ; Vol. 11, No. 12.
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title = "Metabolic Signatures of Adiposity in Young Adults: Mendelian Randomization Analysis and Effects of Weight Change",
keywords = "BODY-MASS INDEX, AMERICAN-HEART-ASSOCIATION, GENOME-WIDE ASSOCIATION, PHYSICAL-ACTIVITY, CARDIOVASCULAR RISK, INSULIN-RESISTANCE, OBESITY, OVERWEIGHT, MORTALITY, COHORT, 3142 Public health care science, environmental and occupational health, 3121 Internal medicine",
author = "Peter W{\"u}rtz and Qin Wang and Kangas, {Antti J.} and Richmond, {Rebecca C.} and Joni Skarp and Mika Tiainen and Tuulia Tynkkynen and Pasi Soininen and Havulinna, {Aki S.} and Marika Kaakinen and Viikari, {Jorma S.} and Savolainen, {Markku J.} and Mika Kahonen and Terho Lehtimaki and Satu Mannisto and Stefan Blankenberg and Tanja Zeller and Jaana Laitinen and Anneli Pouta and Pekka Mantyselka and Mauno Vanhala and Paul Elliott and Pietilainen, {Kirsi H.} and Samuli Ripatti and Veikko Salomaa and Raitakari, {Olli T.} and Marjo-Riitta Jarvelin and Smith, {George Davey} and Mika Ala-Korpela",
year = "2014",
month = "12",
doi = "10.1371/journal.pmed.1001765",
language = "English",
volume = "11",
journal = "PLoS Medicine",
issn = "1549-1277",
publisher = "PUBLIC LIBRARY OF SCIENCE",
number = "12",

}

Würtz, P, Wang, Q, Kangas, AJ, Richmond, RC, Skarp, J, Tiainen, M, Tynkkynen, T, Soininen, P, Havulinna, AS, Kaakinen, M, Viikari, JS, Savolainen, MJ, Kahonen, M, Lehtimaki, T, Mannisto, S, Blankenberg, S, Zeller, T, Laitinen, J, Pouta, A, Mantyselka, P, Vanhala, M, Elliott, P, Pietilainen, KH, Ripatti, S, Salomaa, V, Raitakari, OT, Jarvelin, M-R, Smith, GD & Ala-Korpela, M 2014, 'Metabolic Signatures of Adiposity in Young Adults: Mendelian Randomization Analysis and Effects of Weight Change', PLoS Medicine, vol. 11, no. 12, 1001765. https://doi.org/10.1371/journal.pmed.1001765

Metabolic Signatures of Adiposity in Young Adults : Mendelian Randomization Analysis and Effects of Weight Change. / Würtz, Peter; Wang, Qin; Kangas, Antti J.; Richmond, Rebecca C.; Skarp, Joni; Tiainen, Mika; Tynkkynen, Tuulia; Soininen, Pasi; Havulinna, Aki S.; Kaakinen, Marika; Viikari, Jorma S.; Savolainen, Markku J.; Kahonen, Mika; Lehtimaki, Terho; Mannisto, Satu; Blankenberg, Stefan; Zeller, Tanja; Laitinen, Jaana; Pouta, Anneli; Mantyselka, Pekka; Vanhala, Mauno; Elliott, Paul; Pietilainen, Kirsi H.; Ripatti, Samuli; Salomaa, Veikko; Raitakari, Olli T.; Jarvelin, Marjo-Riitta; Smith, George Davey; Ala-Korpela, Mika.

In: PLoS Medicine, Vol. 11, No. 12, 1001765, 12.2014.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Metabolic Signatures of Adiposity in Young Adults

T2 - Mendelian Randomization Analysis and Effects of Weight Change

AU - Würtz, Peter

AU - Wang, Qin

AU - Kangas, Antti J.

AU - Richmond, Rebecca C.

AU - Skarp, Joni

AU - Tiainen, Mika

AU - Tynkkynen, Tuulia

AU - Soininen, Pasi

AU - Havulinna, Aki S.

AU - Kaakinen, Marika

AU - Viikari, Jorma S.

AU - Savolainen, Markku J.

AU - Kahonen, Mika

AU - Lehtimaki, Terho

AU - Mannisto, Satu

AU - Blankenberg, Stefan

AU - Zeller, Tanja

AU - Laitinen, Jaana

AU - Pouta, Anneli

AU - Mantyselka, Pekka

AU - Vanhala, Mauno

AU - Elliott, Paul

AU - Pietilainen, Kirsi H.

AU - Ripatti, Samuli

AU - Salomaa, Veikko

AU - Raitakari, Olli T.

AU - Jarvelin, Marjo-Riitta

AU - Smith, George Davey

AU - Ala-Korpela, Mika

PY - 2014/12

Y1 - 2014/12

KW - BODY-MASS INDEX

KW - AMERICAN-HEART-ASSOCIATION

KW - GENOME-WIDE ASSOCIATION

KW - PHYSICAL-ACTIVITY

KW - CARDIOVASCULAR RISK

KW - INSULIN-RESISTANCE

KW - OBESITY

KW - OVERWEIGHT

KW - MORTALITY

KW - COHORT

KW - 3142 Public health care science, environmental and occupational health

KW - 3121 Internal medicine

U2 - 10.1371/journal.pmed.1001765

DO - 10.1371/journal.pmed.1001765

M3 - Article

VL - 11

JO - PLoS Medicine

JF - PLoS Medicine

SN - 1549-1277

IS - 12

M1 - 1001765

ER -