Metabotropic Glutamate Receptor 5 Responses Dictate Differentiation of Neural Progenitors to NMDA-Responsive Cells in Fragile X Syndrome

Venkat Swaroop Achuta, Heli Grym, Noora Putkonen, Verna Louhivuori, Virve Karkkainen, Jari Koistinaho, Laurent Roybon, Maija L. Castren

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalDevelopmental Neurobiology
Volume77
Issue number4
Pages (from-to)438-453
Number of pages16
ISSN1932-8451
DOIs
Publication statusPublished - Apr 2017
MoE publication typeA1 Journal article-refereed

Fields of Science

  • induced pluripotent stem cells
  • glutamatergic neurons
  • fragile X syndrome
  • metabotropic glutamate receptor 5
  • 2-methyl-6-(phenylethynyl)-pyridine
  • EMBRYONIC STEM-CELLS
  • OUTER SUBVENTRICULAR ZONE
  • LONG-TERM DEPRESSION
  • RADIAL GLIAL-CELLS
  • FMR1 KNOCKOUT MICE
  • MOUSE MODEL
  • MENTAL-RETARDATION
  • ENDOGENOUS ACTIVATION
  • NEURONAL PROGENITORS
  • PROTEIN-SYNTHESIS
  • 3111 Biomedicine
  • 3112 Neurosciences
  • 3124 Neurology and psychiatry

Cite this

Achuta, Venkat Swaroop ; Grym, Heli ; Putkonen, Noora ; Louhivuori, Verna ; Karkkainen, Virve ; Koistinaho, Jari ; Roybon, Laurent ; Castren, Maija L. / Metabotropic Glutamate Receptor 5 Responses Dictate Differentiation of Neural Progenitors to NMDA-Responsive Cells in Fragile X Syndrome. In: Developmental Neurobiology. 2017 ; Vol. 77, No. 4. pp. 438-453.
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keywords = "induced pluripotent stem cells, glutamatergic neurons, fragile X syndrome, metabotropic glutamate receptor 5, 2-methyl-6-(phenylethynyl)-pyridine, EMBRYONIC STEM-CELLS, OUTER SUBVENTRICULAR ZONE, LONG-TERM DEPRESSION, RADIAL GLIAL-CELLS, FMR1 KNOCKOUT MICE, MOUSE MODEL, MENTAL-RETARDATION, ENDOGENOUS ACTIVATION, NEURONAL PROGENITORS, PROTEIN-SYNTHESIS, 3111 Biomedicine, 3112 Neurosciences, 3124 Neurology and psychiatry",
author = "Achuta, {Venkat Swaroop} and Heli Grym and Noora Putkonen and Verna Louhivuori and Virve Karkkainen and Jari Koistinaho and Laurent Roybon and Castren, {Maija L.}",
year = "2017",
month = "4",
doi = "10.1002/dneu.22419",
language = "English",
volume = "77",
pages = "438--453",
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Metabotropic Glutamate Receptor 5 Responses Dictate Differentiation of Neural Progenitors to NMDA-Responsive Cells in Fragile X Syndrome. / Achuta, Venkat Swaroop; Grym, Heli; Putkonen, Noora; Louhivuori, Verna; Karkkainen, Virve; Koistinaho, Jari; Roybon, Laurent; Castren, Maija L.

In: Developmental Neurobiology, Vol. 77, No. 4, 04.2017, p. 438-453.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Metabotropic Glutamate Receptor 5 Responses Dictate Differentiation of Neural Progenitors to NMDA-Responsive Cells in Fragile X Syndrome

AU - Achuta, Venkat Swaroop

AU - Grym, Heli

AU - Putkonen, Noora

AU - Louhivuori, Verna

AU - Karkkainen, Virve

AU - Koistinaho, Jari

AU - Roybon, Laurent

AU - Castren, Maija L.

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KW - induced pluripotent stem cells

KW - glutamatergic neurons

KW - fragile X syndrome

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KW - OUTER SUBVENTRICULAR ZONE

KW - LONG-TERM DEPRESSION

KW - RADIAL GLIAL-CELLS

KW - FMR1 KNOCKOUT MICE

KW - MOUSE MODEL

KW - MENTAL-RETARDATION

KW - ENDOGENOUS ACTIVATION

KW - NEURONAL PROGENITORS

KW - PROTEIN-SYNTHESIS

KW - 3111 Biomedicine

KW - 3112 Neurosciences

KW - 3124 Neurology and psychiatry

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DO - 10.1002/dneu.22419

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VL - 77

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