Microglial phagocytosis dysfunction in the dentate gyrus is related to local neuronal activity in a genetic model of epilepsy

Virginia Sierra-Torre; Ainhoa Plaza-Zabala; Paolo Bonifazi; Oihane Abiega; Irune Diaz-Aparicio; Saara Tegelberg; Anna-Elina Lehesjoki; Jorge Valero; Amanda Sierra

doi:10.1111/epi.16692

Microglial phagocytosis dysfunction in the dentate gyrus is related to local neuronal activity in a genetic model of epilepsy

Virginia Sierra-Torre, Ainhoa Plaza-Zabala, Paolo Bonifazi, Oihane Abiega, Irune Diaz-Aparicio, Saara Tegelberg, Anna-Elina Lehesjoki, Jorge Valero, Amanda Sierra

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Epilepsia
Volume	61
Issue number	11
Pages (from-to)	2593-2608
Number of pages	16
ISSN	0013-9580
DOIs	https://doi.org/10.1111/epi.16692
Publication status	Published - Nov 2020
MoE publication type	A1 Journal article-refereed

Fields of Science

apoptosis
epilepsy
hippocampus
microglia
phagocytosis
seizures
PROGRESSIVE MYOCLONUS EPILEPSY
CYSTATIN-B
MOUSE MODEL
APOPTOTIC CELLS
CSTB(-/-) MOUSE
ACTIVATION
MUTATION
BRAIN
INFLAMMATION
EXPRESSION
3112 Neurosciences
3124 Neurology and psychiatry

Access to Document

10.1111/epi.16692

epi.16692Final published version, 2.93 MBLicence: CC BY-NC

Cite this

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title = "Microglial phagocytosis dysfunction in the dentate gyrus is related to local neuronal activity in a genetic model of epilepsy",

keywords = "apoptosis, epilepsy, hippocampus, microglia, phagocytosis, seizures, PROGRESSIVE MYOCLONUS EPILEPSY, CYSTATIN-B, MOUSE MODEL, APOPTOTIC CELLS, CSTB(-/-) MOUSE, ACTIVATION, MUTATION, BRAIN, INFLAMMATION, EXPRESSION, 3112 Neurosciences, 3124 Neurology and psychiatry",

author = "Virginia Sierra-Torre and Ainhoa Plaza-Zabala and Paolo Bonifazi and Oihane Abiega and Irune Diaz-Aparicio and Saara Tegelberg and Anna-Elina Lehesjoki and Jorge Valero and Amanda Sierra",

year = "2020",

month = nov,

doi = "10.1111/epi.16692",

language = "English",

volume = "61",

pages = "2593--2608",

journal = "Epilepsia",

issn = "0013-9580",

publisher = "Wiley",

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TY - JOUR

T1 - Microglial phagocytosis dysfunction in the dentate gyrus is related to local neuronal activity in a genetic model of epilepsy

AU - Sierra-Torre, Virginia

AU - Plaza-Zabala, Ainhoa

AU - Bonifazi, Paolo

AU - Abiega, Oihane

AU - Diaz-Aparicio, Irune

AU - Tegelberg, Saara

AU - Lehesjoki, Anna-Elina

AU - Valero, Jorge

AU - Sierra, Amanda

PY - 2020/11

Y1 - 2020/11

KW - apoptosis

KW - epilepsy

KW - hippocampus

KW - microglia

KW - phagocytosis

KW - seizures

KW - PROGRESSIVE MYOCLONUS EPILEPSY

KW - CYSTATIN-B

KW - MOUSE MODEL

KW - APOPTOTIC CELLS

KW - CSTB(-/-) MOUSE

KW - ACTIVATION

KW - MUTATION

KW - BRAIN

KW - INFLAMMATION

KW - EXPRESSION

KW - 3112 Neurosciences

KW - 3124 Neurology and psychiatry

U2 - 10.1111/epi.16692

DO - 10.1111/epi.16692

M3 - Article

SN - 0013-9580

VL - 61

SP - 2593

EP - 2608

JO - Epilepsia

JF - Epilepsia

IS - 11

ER -