Miniaturization and validation of the Ellmans reaction based acetylcholinesterase inhibitory assay into 384-well plate format and screening of a chemical library.

Päivi Järvinen (née Oinonen); Adyary Fallarero; Shikhar Gupta; Gopi C Mohan; Annele Hatakka; Pia Vuorela

doi:10.2174/138620710790980559

Miniaturization and validation of the Ellmans reaction based acetylcholinesterase inhibitory assay into 384-well plate format and screening of a chemical library.

Päivi Järvinen (née Oinonen), Adyary Fallarero, Shikhar Gupta, Gopi C Mohan, Annele Hatakka, Pia Vuorela

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Combinatorial Chemistry & High Throughput Screening
Volume	13
Issue number	3
Pages (from-to)	278-284
Number of pages	7
ISSN	1386-2073
DOIs	https://doi.org/10.2174/138620710790980559
Publication status	Published - Mar 2010
MoE publication type	A1 Journal article-refereed

Fields of Science

Acetylcholinesterase
butyrylcholinesterase
inhibition
high-throughput screening
miniaturization
Ellman's method
THIN-LAYER-CHROMATOGRAPHY
BETA-AMYLOID AGGREGATION
PERIPHERAL ANIONIC SITE
ALZHEIMERS-DISEASE
CHOLINESTERASE-INHIBITORS
MEDICINAL-PLANTS
NATURAL-PRODUCTS
BUTYRYLCHOLINESTERASE
IDENTIFICATION
DISCOVERY
118 Biological sciences
116 Chemical sciences

Access to Document

10.2174/138620710790980559

Cite this

Järvinen (née Oinonen), P., Fallarero, A., Gupta, S., Mohan, G. C., Hatakka, A., & Vuorela, P. (2010). Miniaturization and validation of the Ellmans reaction based acetylcholinesterase inhibitory assay into 384-well plate format and screening of a chemical library. Combinatorial Chemistry & High Throughput Screening, 13(3), 278-284. https://doi.org/10.2174/138620710790980559

@article{31e67ff962814be28cee8416d2a3ad79,

title = "Miniaturization and validation of the Ellmans reaction based acetylcholinesterase inhibitory assay into 384-well plate format and screening of a chemical library.",

keywords = "Acetylcholinesterase, butyrylcholinesterase, inhibition, high-throughput screening, miniaturization, Ellman's method, THIN-LAYER-CHROMATOGRAPHY, BETA-AMYLOID AGGREGATION, PERIPHERAL ANIONIC SITE, ALZHEIMERS-DISEASE, CHOLINESTERASE-INHIBITORS, MEDICINAL-PLANTS, NATURAL-PRODUCTS, BUTYRYLCHOLINESTERASE, IDENTIFICATION, DISCOVERY, 118 Biological sciences, 116 Chemical sciences",

author = "{J{\"a}rvinen (n{\'e}e Oinonen)}, P{\"a}ivi and Adyary Fallarero and Shikhar Gupta and Mohan, {Gopi C} and Annele Hatakka and Pia Vuorela",

year = "2010",

month = mar,

doi = "10.2174/138620710790980559",

language = "English",

volume = "13",

pages = "278--284",

journal = "Combinatorial Chemistry & High Throughput Screening",

issn = "1386-2073",

publisher = "Bentham Science Publishers, Ltd. ",

number = "3",

}

Järvinen (née Oinonen), P , Fallarero, A, Gupta, S, Mohan, GC, Hatakka, A & Vuorela, P 2010, 'Miniaturization and validation of the Ellmans reaction based acetylcholinesterase inhibitory assay into 384-well plate format and screening of a chemical library.', Combinatorial Chemistry & High Throughput Screening, vol. 13, no. 3, pp. 278-284. https://doi.org/10.2174/138620710790980559

Miniaturization and validation of the Ellmans reaction based acetylcholinesterase inhibitory assay into 384-well plate format and screening of a chemical library. / Järvinen (née Oinonen), Päivi ; Fallarero, Adyary; Gupta, Shikhar et al.

In: Combinatorial Chemistry & High Throughput Screening, Vol. 13, No. 3, 03.2010, p. 278-284.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Miniaturization and validation of the Ellmans reaction based acetylcholinesterase inhibitory assay into 384-well plate format and screening of a chemical library.

AU - Järvinen (née Oinonen), Päivi

AU - Fallarero, Adyary

AU - Gupta, Shikhar

AU - Mohan, Gopi C

AU - Hatakka, Annele

AU - Vuorela, Pia

PY - 2010/3

Y1 - 2010/3

KW - Acetylcholinesterase

KW - butyrylcholinesterase

KW - inhibition

KW - high-throughput screening

KW - miniaturization

KW - Ellman's method

KW - THIN-LAYER-CHROMATOGRAPHY

KW - BETA-AMYLOID AGGREGATION

KW - PERIPHERAL ANIONIC SITE

KW - ALZHEIMERS-DISEASE

KW - CHOLINESTERASE-INHIBITORS

KW - MEDICINAL-PLANTS

KW - NATURAL-PRODUCTS

KW - BUTYRYLCHOLINESTERASE

KW - IDENTIFICATION

KW - DISCOVERY

KW - 118 Biological sciences

KW - 116 Chemical sciences

U2 - 10.2174/138620710790980559

DO - 10.2174/138620710790980559

M3 - Article

VL - 13

SP - 278

EP - 284

JO - Combinatorial Chemistry & High Throughput Screening

JF - Combinatorial Chemistry & High Throughput Screening

SN - 1386-2073

IS - 3

ER -