Missing Selectivity of Targeted 4 beta-Phorbol Prodrugs Expected to be Potential Chemotherapeutics

Ilari Tarvainen, Tomas Zimmermann, Pia Heinonen, Maria Helena Jäntti, Jari Yli-Kauhaluoma, Virpi Talman, Henrik Franzyk, Raimo K. Tuominen, Søren Brøgger Christensen

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalACS Medicinal Chemistry Letters
Volume11
Issue number5
Pages (from-to)671-677
Number of pages7
ISSN1948-5875
DOIs
Publication statusPublished - 14 May 2020
MoE publication typeA1 Journal article-refereed

Fields of Science

  • 4 beta-Phorbol ester
  • protease-assisted targeting
  • targeted chemotherapy
  • prodrug
  • prostate-specific antigen
  • prostate-specific membrane antigen
  • PROSTATE-CANCER CELLS
  • ANTIGEN-ACTIVATED THAPSIGARGIN
  • DOWN-REGULATION
  • ANDROGEN RECEPTOR
  • INDUCED APOPTOSIS
  • MEMBRANE ANTIGEN
  • MOLECULAR GRENADES
  • PKC-EPSILON
  • DELTA
  • 12-O-TETRADECANOYLPHORBOL-13-ACETATE
  • 317 Pharmacy

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