Mitochondria-related transcriptional signature is downregulated in adipocytes in obesity: a study of young healthy MZ twins

Sini Heinonen; Maheswary Muniandy; Jana Buzkova; Adil Mardinoglu; Amaia Rodriguez; Gema Fruhbeck; Antti Hakkarainen; Jesper Lundbom; Nina Lundbom; Jaakko Kaprio; Aila Rissanen; Kirsi H. Pietiläinen

doi:10.1007/s00125-016-4121-2

Mitochondria-related transcriptional signature is downregulated in adipocytes in obesity: a study of young healthy MZ twins

Sini Heinonen, Maheswary Muniandy, Jana Buzkova, Adil Mardinoglu, Amaia Rodriguez, Gema Fruhbeck, Antti Hakkarainen, Jesper Lundbom, Nina Lundbom, Jaakko Kaprio, Aila Rissanen, Kirsi H. Pietiläinen

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Diabetologia
Volume	60
Issue number	1
Pages (from-to)	169-181
Number of pages	13
ISSN	0012-186X
DOIs	https://doi.org/10.1007/s00125-016-4121-2
Publication status	Published - Jan 2017
MoE publication type	A1 Journal article-refereed

Fields of Science

Adipocytes
Gene expression
Mitochondria
Obesity
Twins
TUMOR-NECROSIS-FACTOR
HUMAN ADIPOSE-TISSUE
FAT-CELL SIZE
INSULIN-RESISTANCE
FACTOR-ALPHA
IN-VIVO
ACQUIRED OBESITY
EXPRESSION
MICE
BIOGENESIS
3121 General medicine, internal medicine and other clinical medicine
3142 Public health care science, environmental and occupational health

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10.1007/s00125-016-4121-2

Mitochondria-related transcriptional signatureFinal published version, 457 KB

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Cite this

Heinonen, S., Muniandy, M., Buzkova, J., Mardinoglu, A., Rodriguez, A., Fruhbeck, G., Hakkarainen, A., Lundbom, J., Lundbom, N., Kaprio, J., Rissanen, A., & Pietiläinen, K. H. (2017). Mitochondria-related transcriptional signature is downregulated in adipocytes in obesity: a study of young healthy MZ twins. Diabetologia, 60(1), 169-181. https://doi.org/10.1007/s00125-016-4121-2

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keywords = "Adipocytes, Gene expression, Mitochondria, Obesity, Twins, TUMOR-NECROSIS-FACTOR, HUMAN ADIPOSE-TISSUE, FAT-CELL SIZE, INSULIN-RESISTANCE, FACTOR-ALPHA, IN-VIVO, ACQUIRED OBESITY, EXPRESSION, MICE, BIOGENESIS, 3121 General medicine, internal medicine and other clinical medicine, 3142 Public health care science, environmental and occupational health",

author = "Sini Heinonen and Maheswary Muniandy and Jana Buzkova and Adil Mardinoglu and Amaia Rodriguez and Gema Fruhbeck and Antti Hakkarainen and Jesper Lundbom and Nina Lundbom and Jaakko Kaprio and Aila Rissanen and Pietil{\"a}inen, {Kirsi H.}",

year = "2017",

month = jan,

doi = "10.1007/s00125-016-4121-2",

language = "English",

volume = "60",

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Heinonen, S, Muniandy, M , Buzkova, J, Mardinoglu, A, Rodriguez, A, Fruhbeck, G, Hakkarainen, A , Lundbom, J , Lundbom, N , Kaprio, J , Rissanen, A & Pietiläinen, KH 2017, 'Mitochondria-related transcriptional signature is downregulated in adipocytes in obesity: a study of young healthy MZ twins', Diabetologia, vol. 60, no. 1, pp. 169-181. https://doi.org/10.1007/s00125-016-4121-2

TY - JOUR

T1 - Mitochondria-related transcriptional signature is downregulated in adipocytes in obesity

T2 - a study of young healthy MZ twins

AU - Heinonen, Sini

AU - Muniandy, Maheswary

AU - Buzkova, Jana

AU - Mardinoglu, Adil

AU - Rodriguez, Amaia

AU - Fruhbeck, Gema

AU - Hakkarainen, Antti

AU - Lundbom, Jesper

AU - Lundbom, Nina

AU - Kaprio, Jaakko

AU - Rissanen, Aila

AU - Pietiläinen, Kirsi H.

PY - 2017/1

Y1 - 2017/1

KW - Adipocytes

KW - Gene expression

KW - Mitochondria

KW - Obesity

KW - Twins

KW - TUMOR-NECROSIS-FACTOR

KW - HUMAN ADIPOSE-TISSUE

KW - FAT-CELL SIZE

KW - INSULIN-RESISTANCE

KW - FACTOR-ALPHA

KW - IN-VIVO

KW - ACQUIRED OBESITY

KW - EXPRESSION

KW - MICE

KW - BIOGENESIS

KW - 3121 General medicine, internal medicine and other clinical medicine

KW - 3142 Public health care science, environmental and occupational health

U2 - 10.1007/s00125-016-4121-2

DO - 10.1007/s00125-016-4121-2

M3 - Article

SN - 0012-186X

VL - 60

SP - 169

EP - 181

JO - Diabetologia

JF - Diabetologia

IS - 1

ER -