Mitochondrial biogenesis is transcriptionally repressed in lysosomal lipid storage diseases

King Faisal Yambire; Lorena Fernandez-Mosquera; Robert Steinfeld; Christiane Muehle; Elina Ikonen; Ira Milosevic; Nuno Raimundo

doi:10.7554/eLife.39598

Mitochondrial biogenesis is transcriptionally repressed in lysosomal lipid storage diseases

King Faisal Yambire, Lorena Fernandez-Mosquera, Robert Steinfeld, Christiane Muehle, Elina Ikonen, Ira Milosevic, Nuno Raimundo

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	39598
Journal	eLife
Volume	8
Number of pages	29
ISSN	2050-084X
DOIs	https://doi.org/10.7554/eLife.39598
Publication status	Published - 18 Feb 2019
MoE publication type	A1 Journal article-refereed

Fields of Science

NIEMANN-PICK-DISEASE
NUCLEAR RESPIRATORY FACTORS
ATP-CITRATE LYASE
ACID SPHINGOMYELINASE
GENE-EXPRESSION
DOWN-REGULATION
MODEL
C1
DYSFUNCTION
MECHANISMS
3111 Biomedicine

Access to Document

10.7554/eLife.39598

elife-39598-v1Final published version, 6.96 MBLicence: CC BY

Cite this

Yambire, K. F., Fernandez-Mosquera, L., Steinfeld, R., Muehle, C., Ikonen, E., Milosevic, I., & Raimundo, N. (2019). Mitochondrial biogenesis is transcriptionally repressed in lysosomal lipid storage diseases. eLife, 8, [39598]. https://doi.org/10.7554/eLife.39598

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