The present invention is directed to methods and compositions for making and using chimeric polypeptides that comprise a VEGFR-2 ligand. The chimeric molecules of the present invention retain VEGFR-2 binding activity and an enhanced angiogenic activity as compared to native VEGF-A.
|Publication Year||27 Sep 2011|
|Publication status||Published - 27 Sep 2011|
|MoE publication type||H1 Granted patent|