Modulation of BDNF cleavage by plasminogen-activator inhibitor-1 contributes to Alzheimer's neuropathology and cognitive deficits

Gorka Gerenu, Eva Martisova, Hilda Ferrero, Miguel Carracedo, Tomi Rantamäki, Maria Javier Ramirez, Francisco Javier Gil-Bea

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalBiochimica et Biophysica Acta. Molecular Basis of Disease
Volume1863
Issue number4
Pages (from-to)991-1001
Number of pages11
ISSN0925-4439
DOIs
Publication statusPublished - Apr 2017
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Neurotrophin
  • Plasminogen
  • Beta-amyloid
  • Tau hyperphosphorylation
  • Memory
  • AMYLOID-BETA-PROTEIN
  • TRANSGENIC MOUSE MODEL
  • NEUROTROPHIC-FACTOR
  • A-BETA
  • SYNAPTIC PLASTICITY
  • HIPPOCAMPAL-NEURONS
  • TRKB EXPRESSION
  • TAU PATHOLOGY
  • GROWTH-FACTOR
  • DISEASE
  • 1182 Biochemistry, cell and molecular biology

Cite this

Gerenu, Gorka ; Martisova, Eva ; Ferrero, Hilda ; Carracedo, Miguel ; Rantamäki, Tomi ; Javier Ramirez, Maria ; Javier Gil-Bea, Francisco. / Modulation of BDNF cleavage by plasminogen-activator inhibitor-1 contributes to Alzheimer's neuropathology and cognitive deficits. In: Biochimica et Biophysica Acta. Molecular Basis of Disease. 2017 ; Vol. 1863, No. 4. pp. 991-1001.
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title = "Modulation of BDNF cleavage by plasminogen-activator inhibitor-1 contributes to Alzheimer's neuropathology and cognitive deficits",
keywords = "Neurotrophin, Plasminogen, Beta-amyloid, Tau hyperphosphorylation, Memory, AMYLOID-BETA-PROTEIN, TRANSGENIC MOUSE MODEL, NEUROTROPHIC-FACTOR, A-BETA, SYNAPTIC PLASTICITY, HIPPOCAMPAL-NEURONS, TRKB EXPRESSION, TAU PATHOLOGY, GROWTH-FACTOR, DISEASE, 1182 Biochemistry, cell and molecular biology",
author = "Gorka Gerenu and Eva Martisova and Hilda Ferrero and Miguel Carracedo and Tomi Rantam{\"a}ki and {Javier Ramirez}, Maria and {Javier Gil-Bea}, Francisco",
year = "2017",
month = "4",
doi = "10.1016/j.bbadis.2017.01.023",
language = "English",
volume = "1863",
pages = "991--1001",
journal = "Biochimica et Biophysica Acta. Molecular Basis of Disease",
issn = "0925-4439",
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number = "4",

}

Modulation of BDNF cleavage by plasminogen-activator inhibitor-1 contributes to Alzheimer's neuropathology and cognitive deficits. / Gerenu, Gorka; Martisova, Eva; Ferrero, Hilda; Carracedo, Miguel; Rantamäki, Tomi; Javier Ramirez, Maria; Javier Gil-Bea, Francisco.

In: Biochimica et Biophysica Acta. Molecular Basis of Disease, Vol. 1863, No. 4, 04.2017, p. 991-1001.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Modulation of BDNF cleavage by plasminogen-activator inhibitor-1 contributes to Alzheimer's neuropathology and cognitive deficits

AU - Gerenu, Gorka

AU - Martisova, Eva

AU - Ferrero, Hilda

AU - Carracedo, Miguel

AU - Rantamäki, Tomi

AU - Javier Ramirez, Maria

AU - Javier Gil-Bea, Francisco

PY - 2017/4

Y1 - 2017/4

KW - Neurotrophin

KW - Plasminogen

KW - Beta-amyloid

KW - Tau hyperphosphorylation

KW - Memory

KW - AMYLOID-BETA-PROTEIN

KW - TRANSGENIC MOUSE MODEL

KW - NEUROTROPHIC-FACTOR

KW - A-BETA

KW - SYNAPTIC PLASTICITY

KW - HIPPOCAMPAL-NEURONS

KW - TRKB EXPRESSION

KW - TAU PATHOLOGY

KW - GROWTH-FACTOR

KW - DISEASE

KW - 1182 Biochemistry, cell and molecular biology

U2 - 10.1016/j.bbadis.2017.01.023

DO - 10.1016/j.bbadis.2017.01.023

M3 - Article

VL - 1863

SP - 991

EP - 1001

JO - Biochimica et Biophysica Acta. Molecular Basis of Disease

JF - Biochimica et Biophysica Acta. Molecular Basis of Disease

SN - 0925-4439

IS - 4

ER -