Molecular features encoded in the ctDNA reveal heterogeneity and predict outcome in high-risk aggressive B-cell lymphoma

Leo Meriranta; Amjad Alkodsi; Annika Pasanen; Maija Lepistö; Parisa Mapar; Yngvild Nuvin Blaker; Judit Jorgensen; Marja-Liisa Karjalainen-Lindsberg; Idun Fiskvik; Lars Tore G. Mikalsen; Matias Autio; Magnus Bjorkholm; Mats Jerkeman; Oystein Fluge; Peter Brown; Sirkku Jyrkkio; Harald Holte; Esa Pitkänen; Pekka Ellonen; Sirpa Leppä

doi:10.1182/blood.2021012852

Molecular features encoded in the ctDNA reveal heterogeneity and predict outcome in high-risk aggressive B-cell lymphoma

Leo Meriranta, Amjad Alkodsi, Annika Pasanen, Maija Lepistö, Parisa Mapar, Yngvild Nuvin Blaker, Judit Jorgensen, Marja-Liisa Karjalainen-Lindsberg, Idun Fiskvik, Lars Tore G. Mikalsen, Matias Autio, Magnus Bjorkholm, Mats Jerkeman, Oystein Fluge, Peter Brown, Sirkku Jyrkkio, Harald Holte, Esa Pitkänen, Pekka Ellonen, Sirpa Leppä

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Blood
Volume	139
Issue number	12
Pages (from-to)	1863-1877
Number of pages	15
ISSN	0006-4971
DOIs	https://doi.org/10.1182/blood.2021012852
Publication status	Published - 24 Mar 2022
MoE publication type	A1 Journal article-refereed

Fields of Science

3122 Cancers
Circulating tumor dna
Rituximab
Chemotherapy
Mutations
Phase-3
Dlbcl

Access to Document

10.1182/blood.2021012852

Cite this

Meriranta, L., Alkodsi, A., Pasanen, A., Lepistö, M., Mapar, P., Blaker, Y. N., Jorgensen, J., Karjalainen-Lindsberg, M.-L., Fiskvik, I., Mikalsen, L. T. G., Autio, M., Bjorkholm, M., Jerkeman, M., Fluge, O., Brown, P., Jyrkkio, S., Holte, H., Pitkänen, E., Ellonen, P., & Leppä, S. (2022). Molecular features encoded in the ctDNA reveal heterogeneity and predict outcome in high-risk aggressive B-cell lymphoma. Blood, 139(12), 1863-1877. https://doi.org/10.1182/blood.2021012852

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title = "Molecular features encoded in the ctDNA reveal heterogeneity and predict outcome in high-risk aggressive B-cell lymphoma",

keywords = "3122 Cancers, Circulating tumor dna, Rituximab, Chemotherapy, Mutations, Phase-3, Dlbcl",

author = "Leo Meriranta and Amjad Alkodsi and Annika Pasanen and Maija Lepist{\"o} and Parisa Mapar and Blaker, {Yngvild Nuvin} and Judit Jorgensen and Marja-Liisa Karjalainen-Lindsberg and Idun Fiskvik and Mikalsen, {Lars Tore G.} and Matias Autio and Magnus Bjorkholm and Mats Jerkeman and Oystein Fluge and Peter Brown and Sirkku Jyrkkio and Harald Holte and Esa Pitk{\"a}nen and Pekka Ellonen and Sirpa Lepp{\"a}",

year = "2022",

month = mar,

day = "24",

doi = "10.1182/blood.2021012852",

language = "English",

volume = "139",

pages = "1863--1877",

journal = "Blood",

issn = "0006-4971",

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}

Meriranta, L, Alkodsi, A, Pasanen, A, Lepistö, M, Mapar, P, Blaker, YN, Jorgensen, J, Karjalainen-Lindsberg, M-L, Fiskvik, I, Mikalsen, LTG, Autio, M, Bjorkholm, M, Jerkeman, M, Fluge, O, Brown, P, Jyrkkio, S, Holte, H, Pitkänen, E, Ellonen, P & Leppä, S 2022, 'Molecular features encoded in the ctDNA reveal heterogeneity and predict outcome in high-risk aggressive B-cell lymphoma', Blood, vol. 139, no. 12, pp. 1863-1877. https://doi.org/10.1182/blood.2021012852

TY - JOUR

T1 - Molecular features encoded in the ctDNA reveal heterogeneity and predict outcome in high-risk aggressive B-cell lymphoma

AU - Meriranta, Leo

AU - Alkodsi, Amjad

AU - Pasanen, Annika

AU - Lepistö, Maija

AU - Mapar, Parisa

AU - Blaker, Yngvild Nuvin

AU - Jorgensen, Judit

AU - Karjalainen-Lindsberg, Marja-Liisa

AU - Fiskvik, Idun

AU - Mikalsen, Lars Tore G.

AU - Autio, Matias

AU - Bjorkholm, Magnus

AU - Jerkeman, Mats

AU - Fluge, Oystein

AU - Brown, Peter

AU - Jyrkkio, Sirkku

AU - Holte, Harald

AU - Pitkänen, Esa

AU - Ellonen, Pekka

AU - Leppä, Sirpa

PY - 2022/3/24

Y1 - 2022/3/24

KW - 3122 Cancers

KW - Circulating tumor dna

KW - Rituximab

KW - Chemotherapy

KW - Mutations

KW - Phase-3

KW - Dlbcl

U2 - 10.1182/blood.2021012852

DO - 10.1182/blood.2021012852

M3 - Article

SN - 0006-4971

VL - 139

SP - 1863

EP - 1877

JO - Blood

JF - Blood

IS - 12

ER -